Dissociation between the anti-allodynic effects of fingolimod (FTY720) and desensitization of S1P 1 receptor-mediated G-protein activation in a mouse model of sciatic nerve injury.

Autor: Pondelick AM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Moncayo LV; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Donvito G; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., McLane VD; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Gillespie JC; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Hauser KF; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Spiegel S; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Lichtman AH; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Sim-Selley LJ; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Selley DE; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. Electronic address: Dana.Selley@vcuhealth.org.

Publikováno v: Neuropharmacology [Neuropharmacology] 2024 Dec 15; Vol. 261, pp. 110165. Date of Electronic Publication: 2024 Sep 18.

HIV-1 Tat reduces apical dendritic spine density throughout the trisynaptic pathway in the hippocampus of male transgenic mice.

Autor: McLane VD; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA., Lark ARS; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: Arianna.lark@vcuhealth.org., Nass SR; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: sara.nass@vcuhealth.org., Knapp PE; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA; Department of Anatomy & Neurobiology, Virginia Commonwealth University, Richmond, VA, USA; Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: pamela.knapp@vcuhealth.org., Hauser KF; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA; Department of Anatomy & Neurobiology, Virginia Commonwealth University, Richmond, VA, USA; Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: kurt.hauser@vcuhealth.org.

Publikováno v: Neuroscience letters [Neurosci Lett] 2022 Jun 21; Vol. 782, pp. 136688. Date of Electronic Publication: 2022 May 17.

Effects of HIV gp120 on Neuroinflammation in Immunodeficient vs. Immunocompetent States.

Autor: Arabatzis TJ; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, 11 Hills Beach Road, Biddeford, ME, 04005, USA.; Department of Biology, University of New England College of Arts and Sciences, Biddeford, ME, USA., Wakley AA; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, 11 Hills Beach Road, Biddeford, ME, 04005, USA., McLane VD; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, 11 Hills Beach Road, Biddeford, ME, 04005, USA.; Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Medical College of Virginia (MCV) Campus, P.O. Box 980613, Richmond, VA, 23298-0613, USA., Canonico D; Department of Biology, University of New England College of Arts and Sciences, Biddeford, ME, USA., Cao L; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, 11 Hills Beach Road, Biddeford, ME, 04005, USA. lcao@une.edu.; Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA. lcao@une.edu.

Publikováno v: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2021 Jun; Vol. 16 (2), pp. 437-453. Date of Electronic Publication: 2020 Jul 06.

Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids.

Autor: Hermes DJ; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA., Jacobs IR; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA., Key MC; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA., League AF; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA., Yadav-Samudrala BJ; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA., Xu C; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA., McLane VD; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA., Nass SR; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA., Jiang W; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA.; Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA., Meeker RB; Department of Neurology, University of North Carolina, Chapel Hill, NC, USA., Ignatowska-Jankowska BM; Okinawa Institute of Science and Technology, Neuronal Rhythms in Movement Unit, Okinawa, 904-0495, Japan., Lichtman AH; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA., Li Z; Department of Radiology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA., Wu Z; Department of Radiology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA., Yuan H; Department of Radiology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA., Knapp PE; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA.; Department of Anatomy & Neurobiology, Virginia Commonwealth University, Richmond, VA, USA., Hauser KF; Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA.; Department of Anatomy & Neurobiology, Virginia Commonwealth University, Richmond, VA, USA., Fitting S; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, NC, USA. sfitting@email.unc.edu.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2020 Nov 18; Vol. 17 (1), pp. 345. Date of Electronic Publication: 2020 Nov 18.

A central role for glial CCR5 in directing the neuropathological interactions of HIV-1 Tat and opiates.

Autor: Kim S; Department of Anatomy and Neurobiology, Virginia Commonwealth University School of Medicine, 1217 E. Marshall St, Richmond, VA, 23298-0709, USA., Hahn YK; Department of Anatomy and Neurobiology, Virginia Commonwealth University School of Medicine, 1217 E. Marshall St, Richmond, VA, 23298-0709, USA., Podhaizer EM; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA., McLane VD; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA., Zou S; Department of Anatomy and Neurobiology, Virginia Commonwealth University School of Medicine, 1217 E. Marshall St, Richmond, VA, 23298-0709, USA.; Present Address: BioLegend, Inc., 210 Rustcraft Rd., Dedham, MA, 02026, USA., Hauser KF; Department of Anatomy and Neurobiology, Virginia Commonwealth University School of Medicine, 1217 E. Marshall St, Richmond, VA, 23298-0709, USA.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA.; Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, 23298, USA., Knapp PE; Department of Anatomy and Neurobiology, Virginia Commonwealth University School of Medicine, 1217 E. Marshall St, Richmond, VA, 23298-0709, USA. pamela.knapp@vcuhealth.org.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA. pamela.knapp@vcuhealth.org.; Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, 23298, USA. pamela.knapp@vcuhealth.org.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2018 Oct 10; Vol. 15 (1), pp. 285. Date of Electronic Publication: 2018 Oct 10.