Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase

Autor: Thors, L, Burston, JJ, Alter, BJ, McKinney, MK, Cravatt, BF, Ross, RA, Pertwee, RG, Gereau, RW, Wiley, JL, Fowler, CJ

Inhibitors of fatty acid amide hydrolase (FAAH), the enzyme responsible for the metabolism of the endogenous cannabinoid (CB) receptor ligand anandamide (AEA), are effective in a number of animal models of pain. Here, we investigated a series of isof

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::66188e155db44f7fffc5cabd74822860
https://europepmc.org/articles/PMC2931556/

Veres needle in the pleural space

Autor: Szpak Mw, McKinney Mk, Jenkins Dw, Booker Jl

Publikováno v: Southern medical journal. 76(11)

The Veres needle is designed to allow entry into body cavities without trauma to underlying organs. Its major use has been in the induction of a pneumoperitoneum for peritoneoscopy. An initial successful evaluation of its use was in the pleural space

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36bc124648df3d90c53d05e07526158
https://pubmed.ncbi.nlm.nih.gov/6635727

N -acyl taurines are endogenous lipid messengers that improve glucose homeostasis.

Autor: Grevengoed TJ; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Trammell SAJ; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., McKinney MK; Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037.; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Petersen N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Cardone RL; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06519., Svenningsen JS; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Ogasawara D; Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037.; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Nexøe-Larsen CC; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark., Knop FK; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte, 2820 Hellerup, Denmark., Schwartz TW; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Kibbey RG; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06519., Cravatt BF; Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037; cravatt@scripps.edu gillum@sund.ku.dk.; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Gillum MP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; cravatt@scripps.edu gillum@sund.ku.dk.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Dec 03; Vol. 116 (49), pp. 24770-24778. Date of Electronic Publication: 2019 Nov 18.

Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion.

Autor: Kaczocha M; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794, United States., Lin Q, Nelson LD, McKinney MK, Cravatt BF, London E, Deutsch DG

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2012 May 16; Vol. 3 (5), pp. 364-8. Date of Electronic Publication: 2012 Jan 18.

Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase.

Autor: Thors L; Department of Pharmacology and Clinical Neuroscience, Umeå University, Umeå, Sweden., Burston JJ, Alter BJ, McKinney MK, Cravatt BF, Ross RA, Pertwee RG, Gereau RW 4th, Wiley JL, Fowler CJ

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2010 Jun; Vol. 160 (3), pp. 549-60.