Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections.

Autor: McKinley LN; Department of Chemistry, Pennsylvania State University, 104 Benkovic Building, 376 Science Drive, University Park, PA 16802, USA.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA., Meyer MO; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.; Department of Biochemistry and Molecular Biology, Althouse Room 107, 363 Science Drive, Pennsylvania State University, University Park, PA 16802, USA., Sebastian A; Huck Institutes of Life Sciences, 401 Huck Life Sciences Building, 432 Science Drive, Pennsylvania State University, University Park, PA 16802, USA., Chang BK; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.; Department of Biochemistry and Molecular Biology, Althouse Room 107, 363 Science Drive, Pennsylvania State University, University Park, PA 16802, USA., Messina KJ; Department of Chemistry, Pennsylvania State University, 104 Benkovic Building, 376 Science Drive, University Park, PA 16802, USA.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA., Albert I; Department of Biochemistry and Molecular Biology, Althouse Room 107, 363 Science Drive, Pennsylvania State University, University Park, PA 16802, USA.; Huck Institutes of Life Sciences, 401 Huck Life Sciences Building, 432 Science Drive, Pennsylvania State University, University Park, PA 16802, USA., Bevilacqua PC; Department of Chemistry, Pennsylvania State University, 104 Benkovic Building, 376 Science Drive, University Park, PA 16802, USA.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.; Department of Biochemistry and Molecular Biology, Althouse Room 107, 363 Science Drive, Pennsylvania State University, University Park, PA 16802, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Nov 05. Date of Electronic Publication: 2024 Nov 05.

The Metabolome Weakens RNA Thermodynamic Stability and Strengthens RNA Chemical Stability.

Autor: Sieg JP; Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, United States., McKinley LN; Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, United States., Huot MJ; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Biology, Pennsylvania State University, University Park, Pennsylvania 16802, United States., Yennawar NH; The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, United States., Bevilacqua PC; Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, United States.

Publikováno v: Biochemistry [Biochemistry] 2022 Nov 15; Vol. 61 (22), pp. 2579-2591. Date of Electronic Publication: 2022 Oct 28.

Genome Sequences of Chancellor, Mitti, and Wintermute, Three Subcluster K4 Phages Isolated Using Mycobacterium smegmatis mc ² 155.

Autor: Edgington NP; Department of Biology, Southern Connecticut State University, New Haven, Connecticut, USA., Voshell SM; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Ware VC; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Akoto FF; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Alhout AA; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Atwal GJ; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Balyozian JB; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Cadieux ZA; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Chop BM; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Cresawn SG; Department of Biology, James Madison University, Harrisonburg, Virginia, USA., Cudkevich N; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Faltine-Gonzalez DZ; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Garlena RA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Gilmer BJ; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Graham LH; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Grapel MS; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Haleem MM; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Jacobs-Sera D; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Kenna MA; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Khan MA; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Klein TN; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Korenberg JB; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Lichak BP; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Mageeney CM; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., McKinley LN; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Mendello KR; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Myers CM; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Nguyen AT; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Pasqualucci BA; Department of Biology, Southern Connecticut State University, New Haven, Connecticut, USA., Pope WH; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Pyfer LM; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Ramirez WA; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Reisner JR; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Russell DA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Sapao PA; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Saux VC; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Singh I; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Stoner TH; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Swope RH; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Thoonkuzhy MJ; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Walters ML; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA., Vargas LA; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Veliz CA; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Zhang KD; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Zuilkoski CM; Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA., Hatfull GF; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA gfh@pitt.edu.

Publikováno v: Genome announcements [Genome Announc] 2017 Nov 09; Vol. 5 (45). Date of Electronic Publication: 2017 Nov 09.