Zobrazeno 1 - 10
of 14
pro vyhledávání: '"McKenzie L Ritter"'
Autor:
Kirthikaa Balapattabi, Yavuz Yavuz, Jingwei Jiang, Guorui Deng, Natalia M. Mathieu, McKenzie L. Ritter, Megan A. Opichka, John J. Reho, John D. McCorvy, Pablo Nakagawa, Lisa L. Morselli, Gary C. Mouradian, Jr., Deniz Atasoy, Huxing Cui, Matthew R. Hodges, Curt D. Sigmund, Justin L. Grobe
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112935- (2023)
Summary: Resting metabolic rate (RMR) adaptation occurs during obesity and is hypothesized to contribute to failed weight management. Angiotensin II (Ang-II) type 1 (AT1A) receptors in Agouti-related peptide (AgRP) neurons contribute to the integrati
Externí odkaz:
https://doaj.org/article/232d89e1a4584d099a23a192408018ec
Autor:
Valerie A. Wagner, Guorui Deng, Kristin E. Claflin, McKenzie L. Ritter, Huxing Cui, Pablo Nakagawa, Curt D. Sigmund, Lisa L. Morselli, Justin L. Grobe, Anne E. Kwitek
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
A common preclinical model of hypertension characterized by low circulating renin is the “deoxycorticosterone acetate (DOCA)-salt” model, which influences blood pressure and metabolism through mechanisms involving the angiotensin II type 1 recept
Externí odkaz:
https://doaj.org/article/41540d841a564460be2c9f431689fc37
Autor:
McKenzie L, Ritter, Guorui, Deng, John J, Reho, Yue, Deng, Sarah A, Sapouckey, Megan A, Opichka, Kirthikaa, Balapattabi, Kelsey K, Wackman, Daniel T, Brozoski, Ko-Ting, Lu, William J, Paradee, Katherine N, Gibson-Corley, Huxing, Cui, Pablo, Nakagawa, Lisa L, Morselli, Curt D, Sigmund, Justin L, Grobe
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(12)
RGS (regulator of G protein signaling) family members catalyze the termination of G protein signaling cascades. Single nucleotide polymorphisms in theTo study cell-specific functions of RGS2, a novel gene-targeted mouse harboring a conditional allele
Autor:
Vanessa Oliveira, John J. Reho, Kirthikaa Balapattabi, McKenzie L. Ritter, Natalia M. Mathieu, Megan A. Opichka, Ko-Ting Lu, Connie C. Grobe, Sebastião D. Silva, Kelsey K. Wackman, Pablo Nakagawa, Jeffrey L. Segar, Curt D. Sigmund, Justin L. Grobe
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 323(4)
The renin-angiotensin system (RAS) within the brain is implicated in the control of fluid and electrolyte balance, autonomic functions, blood pressure, and energy expenditure. Mouse models are increasingly used to explore these mechanisms; however, s
Autor:
Natalia M. Mathieu, Pablo Nakagawa, Connie C. Grobe, John J. Reho, Daniel T. Brozoski, Ko-Ting Lu, Kelsey K. Wackman, McKenzie L. Ritter, Jeffrey L. Segar, Justin L. Grobe, Curt D. Sigmund
Publikováno v:
Hypertension. 79:2480-2492
Background: GPCRs (G protein–coupled receptors) are implicated in blood pressure (BP) and fluid intake regulation. There is a developing concept that these effects are mediated by both canonical G protein signaling and noncanonical β-arrestin medi
Autor:
Chetan N. Patil, McKenzie L. Ritter, Kelsey K. Wackman, Vanessa Oliveira, Kirthikaa Balapattabi, Connie C. Grobe, Daniel T. Brozoski, John J. Reho, Pablo Nakagawa, Gary C. Mouradian, Alison J. Kriegel, Anne E. Kwitek, Matthew R. Hodges, Jeffrey L. Segar, Curt D. Sigmund, Justin L. Grobe
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Hypertension characterized by low circulating renin activity accounts for roughly 25%–30% of primary hypertension in humans and can be modeled experimentally via deoxycorticosterone acetate (DOCA)-salt treatment. In this model, phenotypes develop i
Autor:
Kirthikaa Balapattabi, McKenzie L Ritter, Gary C Mouradian, Matthew R Hodges, Curt D Sigmund, Justin L Grobe
Publikováno v:
Hypertension. 79
Obesity represents the single greatest impediment to continued improvements in hypertension and cardiovascular disease. Prolonged obesity is associated with “Resting Metabolic Rate (RMR) adaptation” (ie, reduced RMR relative to body composition),
Autor:
McKenzie L Ritter, Kirthikaa Balapattabi, John J Reho, Kristin E Claflin, Lisa L Morselli, Curt D Sigmund, Justin L Grobe
Publikováno v:
Hypertension. 79
Resting metabolic rate (RMR) adaptation contributes to the maintenance of human obesity, yet mechanisms controlling RMR in lean vs obese states remain poorly defined. Leptin contributes to RMR control in part through suppression of inhibitory Agouti-
Autor:
McKenzie L Ritter, Kirthikaa Balapattabi, Allison K Lowman, Jennifer M Connelly, Dylan J Coss, Peter S LaViolette, Pablo Nakagawa, Curt D Sigmund, Lisa L Morselli, Justin L Grobe
Publikováno v:
Hypertension. 79
Local paracrine versions of the renin-angiotensin (ANG) system within the brain have been implicated in aspects of cardiovascular and metabolic control, including fluid and electrolyte homeostasis, blood pressure, and energy expenditure, and these ef
Autor:
McKenzie L Ritter, Jeffrey L. Segar, John J Reho, Connie C Grobe, Justin L. Grobe, Kirthikaa Balapattabi
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Postnatal growth failure is a common morbidity for preterm infants and is associated with adverse neurodevelopmental outcomes. Although sodium (Na) deficiency early in life impairs somatic growth, its impact on neurocognitive functions has not been e