Výsledky vyhledávání - "McKenzie King"

Small Molecule Inhibitor Screen Reveals Calcium Channel Signaling as a Mechanistic Mediator of Clostridium difficile TcdB-Induced Necrosis

Autor: McKenzie King, Melissa A. Farrow, Benjamin W. Spiller, John A. Shupe, Sarah C. Bloch, Kaycei Moton-Melancon, Nicole M. Chumber, D. Borden Lacy, Mary Kay Washington

Publikováno v: ACS Chem Biol

Clostridioides difficile is the leading cause of nosocomial diarrhea in the United States. The primary virulence factors are two homologous sglucosyltransferase toxins, TcdA and TcdB, that inactivate host Rho-family GTPases. The glucosyltransferase a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc73c87bf52e2809cf36861a6dc889f9
https://europepmc.org/articles/PMC7230009/

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