Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

Autor: McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron

Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)

Abstract Background Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived

Externí odkaz: https://doaj.org/article/6b9df6c997a446a79a45c0e33340dd88

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy

Autor: Hiroyuki Horiguchi, Tyler J. Loftus, Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, McKenzie K. Hollen, Brett P. Weiss, Elizabeth S. Miller, Azra Bihorac, Shawn D. Larson, Alicia M. Mohr, Scott C. Brakenridge, Hironori Tsujimoto, Hideki Ueno, Frederick A. Moore, Lyle L. Moldawer, Philip A. Efron, The Sepsis and Critical Illness Research Center Investigators

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Clinical and technological advances promoting early hemorrhage control and physiologic resuscitation as well as early diagnosis and optimal treatment of sepsis have significantly decreased in-hospital mortality for many critically ill patient populat

Externí odkaz: https://doaj.org/article/3ce85428bd1044cea8904454832403b9

Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

Autor: Quran Wu, Henry V. Baker, Ricardo Ungaro, Maria-Cecilia Lopez, Azra Bihorac, Dina C. Nacionales, Lyle L. Moldawer, Alicia M. Mohr, Scott C. Brakenridge, Michael P. Kladde, Julie A. Stortz, Dijoia B Darden, Christiaan Leeuwenburgh, Marvin L. Dirain, Jaimar Rincon, Zhongkai Wang, Babette Brumback, Frederick A. Moore, Mark S. Segal, Marie-Pierre L. Gauthier, Philip A. Efron, McKenzie K. Hollen, Michael C. Cox, Russell B. Hawkins

Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)
Critical Care

BackgroundSepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived suppressor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d275e86fb2be9ca2e3fa5e89c712ab22
http://link.springer.com/article/10.1186/s13054-019-2628-x

Is persistent critical illness a syndrome of ongoing inflammation/immunosuppression/catabolism?

Autor: Philip A. Efron, McKenzie K. Hollen, Scott C. Brakenridge

Publikováno v: Evidence-Based Practice of Critical Care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ec6c2201679566fdb51be233a63a33e
https://doi.org/10.1016/b978-0-323-64068-8.00050-x

Contributors

Autor: Gareth L. Ackland, Adeel Rafi Ahmed, Djillali Annane, Eman Ansari, Hubertus Axer, Jan Bakker, Ian J. Barbash, John James Bates, Michael Bauer, Amy L. Bellinghausen, William S. Bender, Matthew R. Biery, Alexandra Binnie, Thomas P. Bleck, Christina Boncyk, Jason C. Brainard, Scott C. Brakenridge, Frank Martin Brunkhorst, Tara Cahill, BSc(Physio), Christina Campbell, Jonathan Dale Casey, Jean-Marc Cavaillon, Maurizio Cereda, David J. Cooper, Craig M. Coopersmith, Jennifer Cruz, Cheston B. Cunha, Gerard F. Curley, Allison Dalton, Daniel De Backer, Clifford S. Deutschman, David Devlin, Claudia C. Dos, Tomas Drabek, Laura Dragoi, Martin Dres, Anne M. Drewry, Stephen Duff, Philip A. Efron, Sinéad Egan, MB, Ali A. El, E. Wesley Ely, Laura Evans, Jessica Falco-Walter, Jonathan K. Frogel, Niall D. Ferguson, Joseph S. Fernandez-Moure, Jakub Furmaga, David Foster Gaieski, Ognjen Gajic, Alice Gallo De, Kelly R. Genga, Pierce Geoghegan, Evangelos J. Giamarellos-Bourboulis, Rick Gill, Ewan C. Goligher, Emily K. Gordon, W. Robert Grabenkort, Garima Gupta, Jacob T. Gutsche, Goksel Guven, Paige Guyatt, Nicholas Heming, Cheralyn J. Hendrix, McKenzie K. Hollen, Steven M. Hollenberg, Vivien Hong Tuan Ha, Shahd Horie, Catherine L. Hough, Can Ince, Theodore J. Iwashyna, Judith Jacobi, Marc Jeschke, Nicholas J. Johnson, Jeremy M. Kahn, Lewis J. Kaplan, Mark T. Keegan, Jordan Anthony Kempker, Leo G. Kevin, Yasin A. Khan, Ruth Kleinpell, Kurt Kleinschmidt, Michael Klompas, Patrick M. Kochanek, W. Andrew Kofke, Benjamin Kohl, Andreas Kortgen, David Kung, John G. Laffey, Joel Lage, David William Lappin, Francois Lamontagne, Daniel E. Leisman, Ron Leong, Joshua M. Levine, Andrew T. Levinson, Mitchell M. Levy, Ariane Lewis, Ariel Tamara Slavin, Olivier Lheureux, Vincent X. Liu, Craig Lyons, Jason H. Maley, Atul Malhotra, Joshua A. Marks, Greg S. Martin, Niels D. Martin, Claire Masterson, Yunis Mayasi, Virginie Maxime, Bairbre Aine McNicholas, Jakob McSparron, Maureen O. Meade, Mark E. Mikkelsen, Alicia M. Mohr, Peter Moran, Stephanie Royer Moss, Patrick T. Murray, Patrick J. Neligan, Larry X. Nguyen, Alistair D. Nichol, Katherine Lyn Nugent, Mark E. Nunnally, Michael F. O’Connor, Yewande Odeyemi, Steven M. Opal, Anthony O’Regan, John O’Regan, Michelle O’Shaughnessy, Robert L. Owens, Pratik Pandharipande, Ithan D. Peltan, Anders Perner, Michael R. Pinsky, Greta Piper, Lauren A. Plante, Ariella Pratzer, Jean-Charles Preiser, Hallie C. Prescott, Megan T. Quintana, Lindsay Raab, Jason S. Radowsky, Jesse M. Raiten, Bryan T. G. Reidy, Patrick M. Reilly, Kenneth E. Remy, Emanuele Rezoagli, Zaccaria Ricci, Lisbi Rivas, Bram Rochwerg, Kristen Carey Rock, Claudio Ronco, James A. Russell, Danielle K. Sandsmark, Joshua Iokepa Santos, Babak Sarani, Damon C. Scales, Michael Scully, Jon Sevransky, Sam D. Shemie, Carrie A. Sims, Brian P. Smith, Audrey E. Spelde, Robert David Stevens, B. Taylor Thompson, Samuel A. Tisherman, Mark Trinder, Isaiah R. Turnbull, Ida-Fong Ukor, MBBS, Tom van der Poll, Tjitske S.R. van Engelen, Charles R. Vasquez, Michael A. Vella, William J. Vernick, Gianluca Villa, Jean-Louis Vincent, Amy C. Walker, Keith R. Walley, Lorraine B. Ware, Stuart J. Weiss, Anna E. Garcia, Pauline Whyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b675fbbf239c789d920e89f8796a5709
https://doi.org/10.1016/b978-0-323-64068-8.00004-3