Restraint of Fumarate Accrual by HIF-1α Preserves miR-27a-Mediated Limitation of Interleukin 10 during Infection of Macrophages by Histoplasma capsulatum.

Autor: Evans HM; Division of Infectious Diseases, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA., Schultz DF; Division of Infectious Diseases, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA., Boiman AJ; Division of Infectious Diseases, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA., McKell MC; Immunology Graduate Program, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Qualls JE; Immunology Graduate Program, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Deepe GS Jr; Division of Infectious Diseases, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.

Publikováno v: MBio [mBio] 2021 Dec 21; Vol. 12 (6), pp. e0271021. Date of Electronic Publication: 2021 Nov 09.

Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis.

Autor: Boucher AA; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Rosenfeldt L; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Mureb D; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Shafer J; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Sharma BK; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Lane A; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Crowther RR; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA., McKell MC; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Whitt J; Division of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Alenghat T; Division of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Qualls J; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Antoniak S; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mackman N; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Flick MJ; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Steinbrecher KA; Division of Gastroenterology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Palumbo JS; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2020 Jan; Vol. 18 (1), pp. 91-103. Date of Electronic Publication: 2019 Oct 11.

l-Arginine Synthesis from l-Citrulline in Myeloid Cells Drives Host Defense against Mycobacteria In Vivo.

Autor: Lange SM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.; Immunology Graduate Program, College of Medicine, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., McKell MC; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.; Immunology Graduate Program, College of Medicine, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Schmidt SM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Zhao J; Mass Spectrometry Core, Division of Pathology and Laboratory Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Crowther RR; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.; Immunology Graduate Program, College of Medicine, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.; Medical Scientist Training Program, College of Medicine, University of Cincinnati, Cincinnati, OH 45267., Green LC; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.; Molecular, Cellular, and Biochemical Pharmacology Graduate Program, College of Medicine, University of Cincinnati, Cincinnati, OH 45267., Bricker RL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Arnett E; Texas Biomedical Research Institute, San Antonio, TX 78245; and., Köhler SE; Department of Anatomy and Embryology, Maastricht University, 6229 HA Maastricht, the Netherlands., Schlesinger LS; Texas Biomedical Research Institute, San Antonio, TX 78245; and., Setchell KDR; Mass Spectrometry Core, Division of Pathology and Laboratory Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Qualls JE; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229; joseph.qualls@cchmc.org.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2019 Mar 15; Vol. 202 (6), pp. 1747-1754. Date of Electronic Publication: 2019 Feb 01.

l-Citrulline Metabolism in Mice Augments CD4 ⁺ T Cell Proliferation and Cytokine Production In Vitro , and Accumulation in the Mycobacteria-Infected Lung.

Autor: Lange SM; Laboratory of Dr. Joseph E. Qualls, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Immunology Graduate Program, University of Cincinnati/Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., McKell MC; Laboratory of Dr. Joseph E. Qualls, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Immunology Graduate Program, University of Cincinnati/Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Schmidt SM; Laboratory of Dr. Joseph E. Qualls, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Hossfeld AP; Laboratory of Dr. Joanne Turner, Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH, United States., Chaturvedi V; Laboratory of Dr. Sing Sing Way, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Kinder JM; Laboratory of Dr. Sing Sing Way, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., McAlees JW; Laboratory of Dr. Ian P. Lewkowich, Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Lewkowich IP; Laboratory of Dr. Ian P. Lewkowich, Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Way SS; Laboratory of Dr. Sing Sing Way, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Turner J; Laboratory of Dr. Joanne Turner, Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH, United States.; Texas Biomedical Research Institute, San Antonio, TX, United States., Qualls JE; Laboratory of Dr. Joseph E. Qualls, Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2017 Nov 16; Vol. 8, pp. 1561. Date of Electronic Publication: 2017 Nov 16 (Print Publication: 2017).