Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.

Autor: Navia, M A, McKeever, B M, Springer, J P, Lin, T Y, Williams, H R, Fluder, E M, Dorn, C P, Hoogsteen, K

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; January 1989, Vol. 86 Issue: 1 p7-11, 5p

Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1

Autor: McKeever, B M, Navia, M A, Fitzgerald, P M D, Springer, J P, Leu, C T, Heimbach, J C, Herbert, W K, Sigal, I S, Darke, P L

Publikováno v: Journal of Biological Chemistry; February 1989, Vol. 264 Issue: 4 p1919-1921, 3p

The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands.

Autor: Wilkening RR; Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA. robert_wilkening@merck.com, Ratcliffe RW, Tynebor EC, Wildonger KJ, Fried AK, Hammond ML, Mosley RT, Fitzgerald PM, Sharma N, McKeever BM, Nilsson S, Carlquist M, Thorsell A, Locco L, Katz R, Frisch K, Birzin ET, Wilkinson HA, Mitra S, Cai S, Hayes EC, Schaeffer JM, Rohrer SP

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2006 Jul 01; Vol. 16 (13), pp. 3489-94. Date of Electronic Publication: 2006 May 02.

Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors.

Autor: Smith GM; Merck Research Laboratories, West Point, Pennsylvania 19486., Alexander RS, Christianson DW, McKeever BM, Ponticello GS, Springer JP, Randall WC, Baldwin JJ, Habecker CN

Publikováno v: Protein science : a publication of the Protein Society [Protein Sci] 1994 Jan; Vol. 3 (1), pp. 118-25.

Site-directed mutagenesis of glutathione S-transferase YaYa. Important roles of tyrosine 9 and aspartic acid 101 in catalysis.

Autor: Wang RW; Department of Animal & Exploratory Drug Metabolism, Merck Research Laboratories, Rahway, New Jersey 07065-0900., Newton DJ, Huskey SE, McKeever BM, Pickett CB, Lu AY

Publikováno v: The Journal of biological chemistry [J Biol Chem] 1992 Oct 05; Vol. 267 (28), pp. 19866-71.