Intratumor childhood vaccine-specific CD4 ⁺ T-cell recall coordinates antitumor CD8 ⁺ T cells and eosinophils.

Autor: Brown MC; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA mcb52@duke.edu., Beasley GM; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA., McKay ZP; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Yang Y; Department of Neurosurgery, University of Alabama Division of Neurosurgery, Birmingham, Alabama, USA., Desjardins A; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Randazzo DM; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Landi D; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Ashley DM; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Bigner DD; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Nair SK; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA., Gromeier M; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2023 Apr; Vol. 11 (4).

Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling.

Autor: Brown MC; Department of Neurosurgery, Duke University Medical School, Durham, NC, USA., Mosaheb MM; Department of Molecular Genetics & Microbiology, Duke University Medical School, Durham, NC, USA., Mohme M; Department of Neurosurgery, University of Hamburg Medical Center, Hamburg, Germany., McKay ZP; Department of Neurosurgery, Duke University Medical School, Durham, NC, USA., Holl EK; Department of Surgery, Duke University Medical School, Durham, NC, USA., Kastan JP; University Program in Genetics & Genomics, Duke University, Durham, NC, USA., Yang Y; Department of Pathology, Duke University Medical School, Durham, NC, USA., Beasley GM; Department of Surgery, Duke University Medical School, Durham, NC, USA., Hwang ES; Department of Surgery, Duke University Medical School, Durham, NC, USA., Ashley DM; Department of Neurosurgery, Duke University Medical School, Durham, NC, USA., Bigner DD; Department of Neurosurgery, Duke University Medical School, Durham, NC, USA., Nair SK; Department of Surgery, Duke University Medical School, Durham, NC, USA., Gromeier M; Department of Neurosurgery, Duke University Medical School, Durham, NC, USA. grome001@mc.duke.edu.; Department of Molecular Genetics & Microbiology, Duke University Medical School, Durham, NC, USA. grome001@mc.duke.edu.

Publikováno v: Nature communications [Nat Commun] 2021 Mar 25; Vol. 12 (1), pp. 1858. Date of Electronic Publication: 2021 Mar 25.