A genome-scale yeast library with inducible expression of individual genes.

Autor: Arita Y; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.; RIKEN Centre for Sustainable Resource Science, Wako, Saitama, Japan., Kim G; Calico Life Sciences LLC, South San Francisco, CA, USA., Li Z; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Friesen H; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Turco G; Calico Life Sciences LLC, South San Francisco, CA, USA., Wang RY; Calico Life Sciences LLC, South San Francisco, CA, USA., Climie D; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Usaj M; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Hotz M; Calico Life Sciences LLC, South San Francisco, CA, USA., Stoops EH; Calico Life Sciences LLC, South San Francisco, CA, USA., Baryshnikova A; Calico Life Sciences LLC, South San Francisco, CA, USA., Boone C; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.; RIKEN Centre for Sustainable Resource Science, Wako, Saitama, Japan.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Botstein D; Calico Life Sciences LLC, South San Francisco, CA, USA., Andrews BJ; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., McIsaac RS; Calico Life Sciences LLC, South San Francisco, CA, USA.

Publikováno v: Molecular systems biology [Mol Syst Biol] 2021 Jun; Vol. 17 (6), pp. e10207.

Learning causal networks using inducible transcription factors and transcriptome-wide time series.

Autor: Hackett SR; Calico Life Sciences LLC, South San Francisco, CA, USA., Baltz EA; Google Research, Mountain View, CA, USA., Coram M; Google Research, Mountain View, CA, USA., Wranik BJ; Calico Life Sciences LLC, South San Francisco, CA, USA., Kim G; Calico Life Sciences LLC, South San Francisco, CA, USA., Baker A; Calico Life Sciences LLC, South San Francisco, CA, USA., Fan M; Google Research, Mountain View, CA, USA., Hendrickson DG; Calico Life Sciences LLC, South San Francisco, CA, USA., Berndl M; Google Research, Mountain View, CA, USA., McIsaac RS; Calico Life Sciences LLC, South San Francisco, CA, USA.

Publikováno v: Molecular systems biology [Mol Syst Biol] 2020 Mar; Vol. 16 (3), pp. e9174.

Monomerization of far-red fluorescent proteins.

Autor: Wannier TM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125; timothy_wannier@hms.harvard.edu steve@mayo.caltech.edu., Gillespie SK; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125., Hutchins N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125., McIsaac RS; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125., Wu SY; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada., Shen Y; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada., Campbell RE; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada.; Department of Chemistry, The University of Tokyo, 113-0033 Tokyo, Japan., Brown KS; Department of Chemical and Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Physics, University of Connecticut, Storrs, CT 06269.; Department of Marine Sciences, University of Connecticut, Groton, CT 06340., Mayo SL; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125; timothy_wannier@hms.harvard.edu steve@mayo.caltech.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Nov 27; Vol. 115 (48), pp. E11294-E11301. Date of Electronic Publication: 2018 Nov 13.

Unraveling the message: insights into comparative genomics of the naked mole-rat.

Autor: Lewis KN; Calico Life Sciences LLC, 1170 Veterans Blvd, South San Francisco, CA, 94080, USA., Soifer I; Calico Life Sciences LLC, 1170 Veterans Blvd, South San Francisco, CA, 94080, USA., Melamud E; Calico Life Sciences LLC, 1170 Veterans Blvd, South San Francisco, CA, 94080, USA., Roy M; Calico Life Sciences LLC, 1170 Veterans Blvd, South San Francisco, CA, 94080, USA., McIsaac RS; Calico Life Sciences LLC, 1170 Veterans Blvd, South San Francisco, CA, 94080, USA., Hibbs M; Computer Science Department, Trinity University, San Antonio, TX, 78212, USA., Buffenstein R; Calico Life Sciences LLC, 1170 Veterans Blvd, South San Francisco, CA, 94080, USA. rbuffen@calicolabs.com.

Publikováno v: Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2016 Aug; Vol. 27 (7-8), pp. 259-78. Date of Electronic Publication: 2016 Jun 30.

Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen.

Autor: Thievessen I; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA ithievessen@biomed.uni-erlangen.de., Fakhri N; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Steinwachs J; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Kraus V; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., McIsaac RS; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Gao L; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Chen BC; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Baird MA; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Davidson MW; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Betzig E; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Oldenbourg R; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Waterman CM; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA., Fabry B; Laboratory of Cell and Tissue Morphodynamics, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA; Biophysics Group, Department of Physics, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany; Physiology Course and Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, Massachusetts, USA; Third Physics Institute-Biophysics, Georg-August-University, Göttingen, Germany; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA; California Life Company, South San Francisco, California, USA; **Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; Department of Chemistry, Stony Brook University, Stony Brook, New York, USA; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan; Department of Biological Science, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2015 Nov; Vol. 29 (11), pp. 4555-67. Date of Electronic Publication: 2015 Jul 20.