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Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.

Autor: Bragg RM; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225., Coffey SR; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225., Cantle JP; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225., Hu S; School of Medicine, Tsinghua University, Beijing, China.; Division of Experimental Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Singh S; Division of Experimental Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Legg SRW; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225., McHugh CA; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225., Toor A; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225., Zeitlin SO; Department of Neuroscience, University of Virginia, Charlottesville, VA 22908., Kwak S; CHDI Foundation, Princeton, NJ 08540., Howland D; CHDI Foundation, Princeton, NJ 08540., Vogt TF; CHDI Foundation, Princeton, NJ 08540., Monga SP; Division of Experimental Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA USA; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA USA., Carroll JB; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham WA 98225.; Department of Neurology, University of Washington, Seattle, WA 98104-2499.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 26. Date of Electronic Publication: 2023 Jun 26.