Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides.

Autor: Messenger SR; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington, New Zealand., McGuinniety EMR; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington, New Zealand., Stevenson LJ; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington, New Zealand.; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Owen JG; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington, New Zealand., Challis GL; Department of Chemistry, University of Warwick, Coventry, UK.; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, UK.; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Monash University, Clayton, Victoria, Australia., Ackerley DF; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand. David.Ackerley@vuw.ac.nz.; Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington, New Zealand. David.Ackerley@vuw.ac.nz., Calcott MJ; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand. Mark.Calcott@vuw.ac.nz.; Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington, New Zealand. Mark.Calcott@vuw.ac.nz.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2024 Feb; Vol. 20 (2), pp. 251-260. Date of Electronic Publication: 2023 Nov 23.