Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor.

Autor: Boomer J; University of Kansas School of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Kansas City, Kansas, United States., Choi J; University of Kansas School of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Kansas City, Kansas, United States., Alsup A; University of Kansas School of Medicine, Pulmonary, Critical Care and Sleep Medicine , Kansas City, Kansas, United States., McGregor MC; Washington University in St Louis School of Medicine, Division of Pulmonary and Critical Care Medicine, St Louis, Missouri, United States., Lieu J; Washington University in St Louis School of Medicine, Division of Pulmonary and Critical Care Medicine , St Louis, Missouri, United States., Johnson C; Washington University School of Medicine in Saint Louis, Pulmonary/Critical Care Medicine, St Louis, Missouri, United States., Hall C; University of Kansas School of Medicine, Pulmonary Medicine and Critical Care, Kansas City, Kansas, United States., Shi X; University of Kansas School of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Kansas City, Kansas, United States., Kim T; University of Kansas School of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Kansas City, Kansas, United States., Goss C; Washington University in Saint Louis School of Medicine, Biostatistics, Saint Louis, Missouri, United States., Lew D; Washington University in Saint Louis School of Medicine, Biostatistics, Saint Louis, Missouri, United States., Christenson S; University of California San Francisco, Pulmonary & Critical Care, San Francisco, California, United States., Woodruff PG; University of California San Francisco, Division of Pulmonary and Critical Care Medicine, Department of Medicine and CVRI, San Francisco, California, United States., Hastie A; Wake Forest School of Medicine, Center for Genomics and Personalized Medicine Research, School of Medicine, Winston-Salem, North Carolina, United States., Mauger D; Pennsylvania State University, Division of Statistics and Bioinformatics, Department of Public Health Sciences, , Hershey, Pennsylvania, United States., Wenzel SE; University of Pittsburgh School of Medicine, Department of Environmental and Occupation Health, Pittsburgh, Pennsylvania, United States., Hoffman EA; University of Iowa Hospitals and Clinics, 8Department of Radiology, Biomedical Engineering, and Medicine, Iowa City, Iowa, United States., Schechtman KB; Washington University in Saint Louis, Biostatistics, Saint Louis, Missouri, United States., Castro M; University of Kansas School of Medicine, Pulmonary, Critical Care and Sleep Medicine, Kansas City, Kansas, United States; mcastro2@kumc.edu.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Jun 27. Date of Electronic Publication: 2024 Jun 27.

Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts.

Autor: Trivedi AP; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Hall C; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Goss CW; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Lew D; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Krings JG; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., McGregor MC; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Samant M; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Sieren JP; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Li H; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Schechtman KB; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Schirm J; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., McEleney S; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Peterson S; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Moore WC; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Bleecker ER; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Meyers DA; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Israel E; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Washko GR; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Levy BD; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Leader JK; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Wenzel SE; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Fahy JV; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Schiebler ML; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Fain SB; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Jarjour NN; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Mauger DT; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Reinhardt JM; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Newell JD Jr; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Hoffman EA; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Castro M; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.)., Sheshadri A; From the Division of Pulmonary, Critical Care, and Sleep Medicine, Rush University Medical Center, Chicago, Ill (A.P.T.); Division of Pulmonary and Critical Care Medicine, University of Kansas School of Medicine, Kansas City, KS 66103-2937 (C.H., M.C.); Division of Biostatistics (C.W.G., D.L., K.B.S.), Division of Pulmonary and Critical Care Medicine (J.G.K., M.C.M., M.S.), Washington University School of Medicine, St Louis, Mo; Department of Radiology, University of Iowa, Iowa City, Iowa (J.P.S., J.M.R., J.D.N., E.A.H.); Department of Medicine, University of Arizona, Tucson, Ariz (H.L., E.R.B., D.A.M.); VIDA Diagnostics, Coralville, Iowa (J.S., S.M., S.P.); Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC (W.C.M.); Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass (E.I., G.R.W., B.D.L.); Department of Radiology (J.K.L.) and Division of Pulmonary, Allergy and Critical Care Medicine (S.E.W.), University of Pittsburgh, Pittsburgh, Pa; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, Calif (J.V.F.); Department of Radiology (M.L.S., S.B.F.) and Division of Allergy, Pulmonary and Critical Care Medicine (N.N.J.), University of Wisconsin, Madison, Wis; Department of Public Health Sciences, Penn State Eberly College of Science, University Park, Pa (D.T.M.); and Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex (A.S.).

Publikováno v: Radiology [Radiology] 2022 Aug; Vol. 304 (2), pp. 450-459. Date of Electronic Publication: 2022 Apr 26.

Reply to Yilmaz: Selection of Biologics for Type 2-High Asthma.

Autor: McGregor MC; Washington University School of MedicineSt. Louis, Missouriand., Krings J; Washington University School of MedicineSt. Louis, Missouriand., Nair P; McMaster UniversityHamilton, Ontario, Canada., Castro M; Washington University School of MedicineSt. Louis, Missouriand.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2019 Sep 15; Vol. 200 (6), pp. 791-792.

Role of Biologics in Asthma.

Autor: McGregor MC; 1 Division of Pulmonary and Critical Care, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri; and., Krings JG; 1 Division of Pulmonary and Critical Care, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri; and., Nair P; 2 Division of Respirology, Department of Medicine, St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, Ontario, Canada., Castro M; 1 Division of Pulmonary and Critical Care, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri; and.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2019 Feb 15; Vol. 199 (4), pp. 433-445.