Zobrazeno 1 - 10
of 18
pro vyhledávání: '"McGinnis, LM"'
A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition
Autor:
Maher, Jacquelyn, Wei, K, Piecewicz, SM, McGinnis, LM, Taniguchi, CM, Wiegand, SJ, Anderson, K, Chan, CWM, Mulligan, KX, Kuo, D, Yuan, J
Publikováno v:
Maher, Jacquelyn; Wei, K; Piecewicz, SM; McGinnis, LM; Taniguchi, CM; Wiegand, SJ; et al.(2013). A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6sw8z39m
Insulin initiates diverse hepatic metabolic responses, including gluconeogenic suppression and induction of glycogen synthesis and lipogenesis. The liver possesses a rich sinusoidal capillary network with a higher degree of hypoxia and lower gluconeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::b631c86cb5f47ea65fbd5052495325d1
http://www.escholarship.org/uc/item/6sw8z39m
http://www.escholarship.org/uc/item/6sw8z39m
Akademický článek
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Akademický článek
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Autor:
Nabet BY; Genentech Inc., South San Francisco CA, USA. Electronic address: nabet.barzin@gene.com., Hamidi H; Genentech Inc., South San Francisco CA, USA., Lee MC; Genentech Inc., South San Francisco CA, USA., Banchereau R; Genentech Inc., South San Francisco CA, USA., Morris S; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Adler L; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Gayevskiy V; Genentech Inc., South San Francisco CA, USA; Rancho Biosciences, San Diego, CA, USA., Elhossiny AM; Genentech Inc., South San Francisco CA, USA., Srivastava MK; Genentech Inc., South San Francisco CA, USA., Patil NS; Genentech Inc., South San Francisco CA, USA., Smith KA; Genentech Inc., South San Francisco CA, USA., Jesudason R; Genentech Inc., South San Francisco CA, USA., Chan C; Genentech Inc., South San Francisco CA, USA., Chang PS; Genentech Inc., South San Francisco CA, USA., Fernandez M; Genentech Inc., South San Francisco CA, USA., Rost S; Genentech Inc., South San Francisco CA, USA., McGinnis LM; Genentech Inc., South San Francisco CA, USA., Koeppen H; Genentech Inc., South San Francisco CA, USA., Gay CM; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Minna JD; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-8593, USA; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA; Departments of Internal Medicine and Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA., Heymach JV; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Chan JM; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10016, USA., Rudin CM; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10016, USA; Weill Cornell Medical College, New York, NY 10065, USA., Byers LA; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Liu SV; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Reck M; Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany., Shames DS; Genentech Inc., South San Francisco CA, USA. Electronic address: shames.david@gene.com.
Publikováno v:
Cancer cell [Cancer Cell] 2024 Mar 11; Vol. 42 (3), pp. 429-443.e4. Date of Electronic Publication: 2024 Feb 15.
Autor:
McGinnis LM; Department of Research Pathology, Genentech, Inc, South San Francisco, CA, USA., Ibarra-Lopez V; Department of Research Pathology, Genentech, Inc, South San Francisco, CA, USA., Rost S; Department of Research Pathology, Genentech, Inc, South San Francisco, CA, USA., Ziai J; Department of Research Pathology, Genentech, Inc, South San Francisco, CA, USA.
Publikováno v:
The Journal of pathology [J Pathol] 2021 Jul; Vol. 254 (4), pp. 405-417. Date of Electronic Publication: 2021 May 06.
Autor:
Granja JM; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.; Biophysics Program, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Klemm S; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. klemm@stanford.edu., McGinnis LM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. lisa.mcginnis@stanford.edu.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. lisa.mcginnis@stanford.edu., Kathiria AS; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Mezger A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Corces MR; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Parks B; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University School of Engineering, Stanford, CA, USA., Gars E; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Liedtke M; Department of Medicine, Division of Hematology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Zheng GXY; 10x Genomics, Pleasanton, CA, USA., Chang HY; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA., Majeti R; Department of Medicine, Division of Hematology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Greenleaf WJ; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA. wjg@stanford.edu.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. wjg@stanford.edu.; Department of Applied Physics, Stanford University, Stanford, CA, USA. wjg@stanford.edu.; Chan-Zuckerberg Biohub, San Francisco, CA, USA. wjg@stanford.edu.
Publikováno v:
Nature biotechnology [Nat Biotechnol] 2019 Dec; Vol. 37 (12), pp. 1458-1465. Date of Electronic Publication: 2019 Dec 02.
Autor:
McGinnis LM; Department of Pathology, Stanford University Medical Center, Stanford., Nybakken G; Department of Pathology, Kaiser Permanente Santa Clara Medical Center, Santa Clara, CA., Ma L; Department of Pathology, Stanford University Medical Center, Stanford., Arber DA; Department of Pathology, University of Chicago, Chicago, IL.
Publikováno v:
The American journal of surgical pathology [Am J Surg Pathol] 2018 Jul; Vol. 42 (7), pp. 885-890.
Autor:
Taniguchi CM; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford, California, USA., Finger EC, Krieg AJ, Wu C, Diep AN, LaGory EL, Wei K, McGinnis LM, Yuan J, Kuo CJ, Giaccia AJ
Publikováno v:
Nature medicine [Nat Med] 2013 Oct; Vol. 19 (10), pp. 1325-30. Date of Electronic Publication: 2013 Sep 15.
Autor:
Wei K; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., Piecewicz SM; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., McGinnis LM; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., Taniguchi CM; Division of Radiation Oncology Stanford University School of Medicine, Stanford, California 94305, USA., Wiegand SJ; Regeneron Pharmaceuticals, Incorporated, Tarrytown, New York, 10591, USA., Anderson K; Regeneron Pharmaceuticals, Incorporated, Tarrytown, New York, 10591, USA., Chan CW; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., Mulligan KX; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville TN 37232, USA., Kuo D; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., Yuan J; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., Vallon M; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA., Morton L; Regeneron Pharmaceuticals, Incorporated, Tarrytown, New York, 10591, USA., Lefai E; INSERM U 1060, INRA 1235, Universite de Lyon, Faculté de Médecine Lyon Sud - BP12, 69921 OULLINS Cedex, France., Simon MC; Abramson Family Cancer Research Institute, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, 19104, USA., Maher JJ; UCSF Liver Center, San Francisco General Hospital, 1001 Potrero Ave. Building 40, Room 4102, San Francisco, CA 94110., Mithieux G; Inserm U855/Université Lyon, Faculté Lyon Est Laennec, 7 rue Guillaume Paradin, 69372 Lyon cedex 08, France., Rajas F; Inserm U855/Université Lyon, Faculté Lyon Est Laennec, 7 rue Guillaume Paradin, 69372 Lyon cedex 08, France., Annes J; Division of Endocrinology and Metabolism, Stanford University School of Medicine, Stanford, California 94305, USA., McGuinness OP; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville TN 37232, USA., Thurston G; Regeneron Pharmaceuticals, Incorporated, Tarrytown, New York, 10591, USA., Giaccia AJ; Division of Radiation Oncology Stanford University School of Medicine, Stanford, California 94305, USA., Kuo CJ; Division of Hematology, Stanford University School of Medicine, Stanford, California 94305, USA.
Publikováno v:
Nature medicine [Nat Med] 2013 Oct; Vol. 19 (10), pp. 1331-1337. Date of Electronic Publication: 2013 Sep 15.
Autor:
McGinnis LM, Kuo CJ
Publikováno v:
Nature medicine [Nat Med] 2012 Jan 06; Vol. 18 (1), pp. 22-4. Date of Electronic Publication: 2012 Jan 06.