Výsledky vyhledávání - "McFeely, Daniel"

Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity† †Electronic supplementary information (ESI) available: Experimental details include materials, instrumentation, synthesis and characterization, photoactivity against bacteria, transient electronic absorption spectroscopy and computational analysis. Table S1–S5 show the data of X-ray structures and DFT analysis, Fig. S1–S12 give X-ray crystal structures and dark stability of the compound, the extinction coefficients for cis-[Ru(bpy)2(INH)2]2+, HR-MS peaks for the photoproduct, the stability of the photoproduct, 1H NMR spectrum and HPLC analysis upon photoirradiation, photoactivity against bacteria and the pictures of DFT analysis. CCDC 1474453. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc03028a Click here for additional data file. Click here for additional data file

Autor: Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G., Sadler, Peter J.

Publikováno v: Chemical Science

The Ru(ii) complex, cis-[Ru(bpy)2(INH)2]2+ is inactive in the dark but highly active towards mycobacteria on photoactivation with visible light when it releases the antituberculosis drug isoniazid (INH).
The novel photoactive ruthenium(ii) compl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba6a3db8fcd2ac20f9d4b7174e14ed22
http://europepmc.org/articles/PMC5365061

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The role of the N-glycolyl modification in Mycobacterial peptidoglycan synthesis and survival

Autor: McFeely, Daniel

Mycobacteria are acid fast bacilli responsible for the wide spread global diseases tuberculosis and leprosy. The increased persistence of multidrug resistant (MDR) mycobacterial strains has led to the focus on discovery of new and under-utilised cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::060c9f1c54f436d4bd2e4eabc8a27c7b
http://wrap.warwick.ac.uk/137236/1/WRAP_Theses_McFeely_2019.pdf

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Akademický článek

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The external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growth

Autor: Turapov, Obolbek, Loraine, Jessica, Jenkins, Christopher, Barthe, Philippe, Mcfeely, Daniel, Forti, Francesca, Ghisotti, Daniela, Hesek, Dusan, Lee, Mijoon, Bottrill, Andrew, Vollmer, Waldemar, Mobashery, Shahriar, Cohen-Gonsaud, Martin, Mukamolova, Galina

Publikováno v: Open Biology, Vol 5, Iss 7 (2015)
Open Biology
Open Biology, Royal Society, 2015, 5 (7), pp.150025. ⟨10.1098/rsob.150025⟩
Open Biology, 2015, 5 (7), pp.150025. ⟨10.1098/rsob.150025⟩

International audience; PknB is an essential serine/threonine protein kinase required for mycobacterial cell division and cell-wall biosynthesis. Here we demonstrate that overexpression of the external PknB_PASTA domain in mycobacteria results in del

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::125d6250e0f3ac5e03b5ce6ee0b5da90
https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150025

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SCHEDULING TO ACHIEVE MULTIPLE CRITERIA IN AN AIR FORCE DEPOT CNC MACHINE SHOP.

Autor: McFeely, Daniel J.¹, Simpson III., Wendell P.², Simons Jr., Jacob V.³

Publikováno v: Production & Inventory Management Journal. 1997 1st Quarter, Vol. 38 Issue 1, p72-79. 8p.

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Akademický článek

AN ARGUMENT FOR RESTRICTING THE PATENT RIGHTS OF THOSE WHO MISUSE THE U.S. PATENT SYSTEM TO EARN MONEY THROUGH LITIGATION.

Autor: McFeely, Daniel J.

Publikováno v: Arizona State Law Journal; 2008, Vol. 40 Issue 1, preceding p290-325, 37p

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