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Akademický článek

A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models.

Autor: Warner NL; HDT Bio, Seattle, WA 98102, USA., Archer J; HDT Bio, Seattle, WA 98102, USA., Park S; HDT Bio, Seattle, WA 98102, USA., Singh G; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA., McFadden KM; Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA., Kimura T; HDT Bio, Seattle, WA 98102, USA., Nicholes K; HDT Bio, Seattle, WA 98102, USA., Simpson A; HDT Bio, Seattle, WA 98102, USA., Kaelber JT; Institute for Quantitative Biomedicine, Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA., Hawman DW; Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT 59840, USA., Feldmann H; Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT 59840, USA., Khandhar AP; HDT Bio, Seattle, WA 98102, USA., Berglund P; HDT Bio, Seattle, WA 98102, USA., Vogt MR; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.; Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA., Erasmus JH; HDT Bio, Seattle, WA 98102, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Aug 07; Vol. 16 (759), pp. eadi1625. Date of Electronic Publication: 2024 Aug 07.

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Akademický článek

BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance.

Autor: Donoghue LJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Markovetz MR; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Morrison CB; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Chen G; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., McFadden KM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Sadritabrizi T; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Gutay MI; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Kato T; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Rogers TD; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Snead JY; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Livraghi-Butrico A; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Button B; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Ehre C; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.; Division of Pediatric Pulmonology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Grubb BR; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States., Hill DB; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina, United States., Kelada SNP; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Dec 01; Vol. 325 (6), pp. L765-L775. Date of Electronic Publication: 2023 Oct 17.

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Akademický článek

Collaborative cross strain CC011/UncJ as a novel mouse model of T2-high, severe asthma.

Autor: Donoghue LJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., McFadden KM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Vargas D; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Smith GJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Immormino RM; Department of Pediatrics, Division of Allergy and Immunology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Moran TP; Department of Pediatrics, Division of Allergy and Immunology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Kelada SNP; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. samir_kelada@med.unc.edu.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. samir_kelada@med.unc.edu.

Publikováno v: Respiratory research [Respir Res] 2023 Jun 09; Vol. 24 (1), pp. 153. Date of Electronic Publication: 2023 Jun 09.

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Akademický článek

A Locus on Chromosome 15 Contributes to Acute Ozone-induced Lung Injury in Collaborative Cross Mice.

Autor: Tovar A; Department of Genetics.; Curriculum in Genetics and Molecular Biology, and., Smith GJ; Department of Genetics.; Curriculum in Toxicology and Environmental Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and., Nalesnik MB; Curriculum in Toxicology and Environmental Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and., Thomas JM; Department of Genetics., McFadden KM; Department of Genetics., Harkema JR; Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan., Kelada SNP; Department of Genetics.; Curriculum in Genetics and Molecular Biology, and.; Curriculum in Toxicology and Environmental Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2022 Nov; Vol. 67 (5), pp. 528-538.

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Akademický článek

Integrative analysis reveals mouse strain-dependent responses to acute ozone exposure associated with airway macrophage transcriptional activity.

Autor: Tovar A; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Genetics & Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Crouse WL; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Bioinformatics & Computational Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Smith GJ; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Toxicology & Environmental Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Thomas JM; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Keith BP; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Bioinformatics & Computational Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., McFadden KM; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Moran TP; Department of Pediatrics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Center for Environmental Medicine, Asthma, and Lung Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Furey TS; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Genetics & Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Bioinformatics & Computational Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Kelada SNP; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Genetics & Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Bioinformatics & Computational Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Curriculum in Toxicology & Environmental Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Center for Environmental Medicine, Asthma, and Lung Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2022 Jan 01; Vol. 322 (1), pp. L33-L49. Date of Electronic Publication: 2021 Nov 10.

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Akademický článek

Transperineal Ultrasound in the Diagnosis of Proctitis in the Emergency Department.

Autor: Al Mulhim AA; Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts; Center for Ultrasound Research and Education (CURE) at Massachusetts General Hospital, Boston, Massachusetts; Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Schulwolf SL; Center for Ultrasound Research and Education (CURE) at Massachusetts General Hospital, Boston, Massachusetts., McFadden KM; Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts; Center for Ultrasound Research and Education (CURE) at Massachusetts General Hospital, Boston, Massachusetts; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Shokoohi H; Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts; Center for Ultrasound Research and Education (CURE) at Massachusetts General Hospital, Boston, Massachusetts.

Publikováno v: The Journal of emergency medicine [J Emerg Med] 2021 May; Vol. 60 (5), pp. e119-e124. Date of Electronic Publication: 2021 Jan 07.

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