ATR inhibition radiosensitizes cells through augmented DNA damage and G2 cell cycle arrest abrogation.

Autor: Bright SJ; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Manandhar M; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Flint DB; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Kolachina R; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Biosciences, Rice University, Houston, Texas, USA., Ben Kacem M; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Martinus DK; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Turner BX; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Qureshi I; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Emory University School of Medicine, Emory University, Atlanta, Georgia, USA., McFadden CH; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Marinello PC; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Shaitelman SF; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Sawakuchi GO; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Publikováno v: JCI insight [JCI Insight] 2024 Oct 08; Vol. 9 (19). Date of Electronic Publication: 2024 Oct 08.

Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions.

Autor: Flint DB; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bright SJ; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., McFadden CH; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Konishi T; Single Cell Radiation Biology Group, Institute for Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan., Ohsawa D; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.; Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan., Turner B; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lin SH; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Grosshans DR; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Chiu HS; Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA., Sumazin P; Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA., Shaitelman SF; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sawakuchi GO; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Publikováno v: Medical physics [Med Phys] 2021 Jun; Vol. 48 (6), pp. 3243-3261. Date of Electronic Publication: 2021 May 09.

Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death.

Autor: Bright SJ; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Flint DB; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chakraborty S; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., McFadden CH; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yoon DS; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bronk L; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Titt U; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mohan R; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Grosshans DR; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Sumazin P; Texas Children's Cancer Center and Department of Pediatrics, Baylor College of Medicine, Houston, Texas., Shaitelman SF; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Asaithamby A; Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas., Sawakuchi GO; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: gsawakuchi@mdanderson.org.

Publikováno v: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2019 Dec 01; Vol. 105 (5), pp. 1119-1125. Date of Electronic Publication: 2019 Aug 16.

Time-Lapse Monitoring of DNA Damage Colocalized With Particle Tracks in Single Living Cells.

Autor: McFadden CH; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hallacy TM; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Physics and Astronomy, Rice University, Houston, Texas., Flint DB; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas, Houston, Texas., Granville DA; Department of Medical Physics, The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada., Asaithamby A; Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Centre, Dallas, Texas., Sahoo N; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Akselrod MS; Crystal Growth Division, Landauer, Inc, Stillwater, Oklahoma., Sawakuchi GO; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas, Houston, Texas. Electronic address: gsawakuchi@mdanderson.org.

Publikováno v: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2016 Sep 01; Vol. 96 (1), pp. 221-7. Date of Electronic Publication: 2016 Apr 16.

Sanitary laws in relation to public health.

Autor: McFADDEN CH

Publikováno v: The Sanitarian [Sanitarian] 1945 Nov-Dec; Vol. 8, pp. 100-5.