Intratumoural expression of deoxycytidylate deaminase or ribonuceotide reductase subunit M1 expression are not related to survival in patients with resected pancreatic cancer given adjuvant chemotherapy

Autor: Elander, NO, Aughton, K, Ghaneh, P, Neoptolemos, JP, Palmer, DH, Cox, TF, Campbell, F, Costello, E, Halloran, CM, Mackey, JR, Scarfe, AG, Valle, JW, McDonald, AC, Carter, R, Tebbutt, NC, Goldstein, D, Shannon, J, Dervenis, C, Glimelius, B, Deakin, M, Charnley, RM, Anthoney, A, Lerch, MM, Mayerle, J, Olah, A, Buchler, MW, Greenhalf, W, Canc, European Study Grp Pancreatic

Publikováno v: British Journal of Cancer
Elander, N O, Aughton, K, Ghaneh, P, Neoptolemos, J P, Palmer, D H, Cox, T F, Campbell, F, Costello, E, Halloran, C M, Mackey, J R, Scarfe, A G, Valle, J W, McDonald, A C, Carter, R, Tebbutt, N C, Goldstein, D, Shannon, J, Dervenis, C, Glimelius, B, Deakin, M, Charnley, R M, Anthoney, A, Lerch, M M, Mayerle, J, Oláh, A, Büchler, M W & Greenhalf, W 2018, ' Intratumoural expression of deoxycytidylate deaminase or ribonuceotide reductase subunit M1 expression are not related to survival in patients with resected pancreatic cancer given adjuvant chemotherapy ', British Journal of Cancer, vol. 118, no. 8, pp. 1084-1088 . https://doi.org/10.1038/s41416-018-0005-1

Background: Deoxycytidylate deaminase (DCTD) and ribonucleotide reductase subunit M1 (RRM1) are potential prognostic and predictive biomarkers for pyrimidine-based chemotherapy in pancreatic adenocarcinoma. Methods: Immunohistochemical staining of DC

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Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial.

Autor: Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A

Publikováno v: JAMA: Journal of the American Medical Association; 7/11/2012, Vol. 308 Issue 2, p147-156, 10p

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