Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function.

Autor: Rosier K; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven, Belgium., McDevitt MT; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Smet J; Department of Internal Medicine and Pediatrics, Division of Pediatric Neurology and Metabolism, Ghent University Hospital, Ghent, Belgium., Floyd BJ; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Verschoore M; Department of Internal Medicine and Pediatrics, Division of Pediatric Neurology and Metabolism, Ghent University Hospital, Ghent, Belgium., Marcaida MJ; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Bingman CA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Lemmens I; Center for Medical Biotechnology, VIB, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Dal Peraro M; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Tavernier J; Center for Medical Biotechnology, VIB, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Cravatt BF; The Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Gounko NV; VIB-KU Leuven Center for Brain & Disease Research, Electron Microscopy Platform & VIB-Bioimaging Core, Leuven, Belgium.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Vints K; VIB-KU Leuven Center for Brain & Disease Research, Electron Microscopy Platform & VIB-Bioimaging Core, Leuven, Belgium.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Monnens Y; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven, Belgium., Bhalla K; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven, Belgium., Aerts L; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven, Belgium., Rashan EH; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Vanlander AV; Department of Internal Medicine and Pediatrics, Division of Pediatric Neurology and Metabolism, Ghent University Hospital, Ghent, Belgium., Van Coster R; Department of Internal Medicine and Pediatrics, Division of Pediatric Neurology and Metabolism, Ghent University Hospital, Ghent, Belgium., Régal L; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Neurology and Metabolism, UZ Brussel, Brussels, Belgium., Pagliarini DJ; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.; Morgridge Institute for Research, Madison, WI 53715, USA.; Departments of Cell Biology and Physiology, Biochemistry and Molecular Biophysics, and Genetics, Washington University School of Medicine, St Louis, MO 63110, USA., Creemers JWM; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven, Belgium.

Publikováno v: IScience [iScience] 2021 Nov 14; Vol. 24 (12), pp. 103460. Date of Electronic Publication: 2021 Nov 14 (Print Publication: 2021).

Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species.

Autor: Jha P; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland., McDevitt MT; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Gupta R; Morgridge Institute for Research, Madison, WI 53715, USA., Quiros PM; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland., Williams EG; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland., Gariani K; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland., Sleiman MB; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland., Diserens L; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland., Jochem A; Morgridge Institute for Research, Madison, WI 53715, USA., Ulbrich A; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Coon JJ; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Auwerx J; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland. Electronic address: admin.auwerx@epfl.ch., Pagliarini DJ; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: dpagliarini@morgridge.org.

Publikováno v: Cell systems [Cell Syst] 2018 Jun 27; Vol. 6 (6), pp. 722-733.e6. Date of Electronic Publication: 2018 Jun 13.

Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family.

Autor: Reidenbach AG; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Kemmerer ZA; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Aydin D; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Jochem A; Morgridge Institute for Research, Madison, WI 53715, USA., McDevitt MT; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Hutchins PD; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Stark JL; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Stefely JA; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Reddy T; Morgridge Institute for Research, Madison, WI 53715, USA., Hebert AS; Genome Center of Wisconsin, Madison, WI 53706, USA., Wilkerson EM; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Johnson IE; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Bingman CA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Markley JL; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Coon JJ; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; Genome Center of Wisconsin, Madison, WI 53706, USA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Dal Peraro M; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Pagliarini DJ; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: dpagliarini@morgridge.org.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2018 Feb 15; Vol. 25 (2), pp. 154-165.e11. Date of Electronic Publication: 2017 Nov 30.