Meropenem extraction by ex vivo extracorporeal life support circuits

Autor: Honeycutt Christopher Cole, McDaniel Charles Griffin, McKnite Autumn, Hunt J. Porter, Whelan Aviva, Green Danielle J., Watt Kevin M.

Publikováno v: The Journal of ExtraCorporeal Technology, Vol 55, Iss 4, Pp 159-166 (2023)

Background: Meropenem is a broad-spectrum carbapenem-type antibiotic commonly used to treat critically ill patients infected with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. As many of these patients require extracorporeal mem

Externí odkaz: https://doaj.org/article/8ebb966bd28041599a98fa5a737fa1a5

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Aptamer-based factor IXa inhibition preserves hemostasis and prevents thrombosis in a piglet model of ECMO.

Autor: Reed CR; Department of Surgery, Duke University Medical Center and Health System, 2301 Erwin Road, Box 3443, Durham, NC 27710, USA., Bonadonna D; Extracorporeal Life Support, Duke University Medical Center, Durham, NC 27710, USA., Otto JC; Department of Surgery, Duke University Medical Center and Health System, 2301 Erwin Road, Box 3443, Durham, NC 27710, USA., McDaniel CG; Duke University, Durham, NC 27710, USA., Chabata CV; Departments of Surgery; and Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Kuchibhatla M; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27710, USA., Frederiksen J; Department of Surgery, Duke University Medical Center and Health System, 2301 Erwin Road, Box 3443, Durham, NC 27710, USA., Layzer JM; Duke University Clinical and Translational Science Institute, Durham, NC 27710, USA., Arepally GM; Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA., Sullenger BA; Department of Surgery, Duke University Medical Center and Health System, 2301 Erwin Road, Box 3443, Durham, NC 27710, USA., Tracy ET; Department of Surgery, Duke University Medical Center and Health System, 2301 Erwin Road, Box 3443, Durham, NC 27710, USA.; Division of Pediatric Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Dec 11; Vol. 27, pp. 524-534. Date of Electronic Publication: 2021 Dec 11 (Print Publication: 2022).