Zobrazeno 1 - 10
of 7 966
pro vyhledávání: '"McCullagh A"'
Consider a binary mixture model of the form $F_\theta = (1-\theta)F_0 + \theta F_1$, where $F_0$ is standard Gaussian and $F_1$ is a completely specified heavy-tailed distribution with the same support. For a sample of $n$ independent and identically
Externí odkaz:
http://arxiv.org/abs/2407.20162
In large-scale studies with parallel signal-plus-noise observations, the local false discovery rate is a summary statistic that is often presumed to be equal to the posterior probability that the signal is null. We prefer to call the latter quantity
Externí odkaz:
http://arxiv.org/abs/2402.08792
Autor:
Rebecca Clarke, Tehmina Bharucha, Benediktus Yohan Arman, Bevin Gangadharan, Laura Gomez Fernandez, Sara Mosca, Qianqi Lin, Kerlijn Van Assche, Robert Stokes, Susanna Dunachie, Michael Deats, Hamid A. Merchant, Céline Caillet, John Walsby-Tickle, Fay Probert, Pavel Matousek, Paul N. Newton, Nicole Zitzmann, James S. O. McCullagh
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract The global population is increasingly reliant on vaccines to maintain population health with billions of doses used annually in immunisation programmes. Substandard and falsified vaccines are becoming more prevalent, caused by both the degra
Externí odkaz:
https://doaj.org/article/f005fcfa3a62421b8cb44d66f94b298d
In a range of genomic applications, it is of interest to quantify the evidence that the signal at site~$i$ is active given conditionally independent replicate observations summarized by the sample mean and variance $(\bar Y, s^2)$ at each site. We st
Externí odkaz:
http://arxiv.org/abs/2307.01395
Autor:
Lynch, Ruth, McCullagh, Orla
Publikováno v:
Meditari Accountancy Research, 2024, Vol. 32, Issue 7, pp. 65-87.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/MEDAR-06-2023-2050
Autor:
Chee Kin Then, Salome Paillas, Aliu Moomin, Mariya D. Misheva, Rachel A. Moir, Susan M. Hay, David Bremner, Kristine S. Roberts (nee Nellany), Ellen E. Smith, Zeynab Heidari, Daniel Sescu, Xuedan Wang, Alejandro Suárez-Bonnet, Nadine Hay, Sarah L. Murdoch, Ryoichi Saito, Elaina S. R. Collie-Duguid, Shirley Richardson, Simon L. Priestnall, Joan M. Wilson, Mahalakshmi Gurumurthy, Justine S. Royle, Leslie M. Samuel, George Ramsay, Katherine A. Vallis, Kevin R. Foster, James S. O. McCullagh, Anne E. Kiltie
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Background Non-toxic approaches to enhance radiotherapy outcomes are beneficial, particularly in ageing populations. Based on preclinical findings showing that high-fibre diets sensitised bladder tumours to irradiation by modifying the gut m
Externí odkaz:
https://doaj.org/article/b90bc4a81c81485ab1f36d54138de454
Publikováno v:
JCTC 2023
In this work, we demonstrate that Linear Discriminant Analysis (LDA) applied to atomic positions in two different states of a biomolecule produces a good reaction coordinate between those two states. Atomic coordinates of a macromolecule are a direct
Externí odkaz:
http://arxiv.org/abs/2301.03479
Autor:
Natasha E Schoeler, Louise Marston, Laura Lyons, Sally Halsall, Ruchika Jain, Siobhan Titre-Johnson, Maryam Balogun, Simon J R Heales, Simon Eaton, Michael Orford, Elizabeth Neal, Christin Eltze, Elma Stephen, Andrew A Mallick, Finbar O’Callaghan, Shakti Agrawal, Alasdair Parker, Martin Kirkpatrick, Andreas Brunklaus, Ailsa McLellan, Helen McCullagh, Rajib Samanta, Rachel Kneen, Hui Jeen Tan, Anita Devlin, Manish Prasad, Rohini Rattihalli, Helen Basu, Archana Desurkar, Ruth Williams, Penny Fallon, Irwin Nazareth, Nicholas Freemantle, J Helen Cross
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 16 (2024)
Background Many infancy-onset epilepsies have a poor prognosis for seizure control and neurodevelopmental outcome. Ketogenic diets can improve seizures in older children and adults unresponsive to antiseizure medicines. We aimed to determine the effe
Externí odkaz:
https://doaj.org/article/3cbdf6bf151e43c59877574331e8adad
Autor:
Karen Robinson, Mary Godfrey, Deirdre Walsh, Ann Duffy, Karen A Power, Irene O'Byrne Maguire, Noelle Byrne, Mark McCullagh, Yvonne Fallon, Claire O'Regan, Mairead Twohig, Cathal O'Keeffe
Publikováno v:
BMJ Open Quality, Vol 13, Iss 3 (2024)
Objective Learning from adverse outcomes in health and social care is critical to advancing a culture of patient safety and reducing the likelihood of future preventable harm to service users. This review aims to present an overview of all clinical c
Externí odkaz:
https://doaj.org/article/60a14ef90acb4803ab23df4bbd30f535
Autor:
Hanna K. Isotalus, Will J. Carr, Jonathan Blackman, George G. Averill, Oliver Radtke, James Selwood, Rachel Williams, Elizabeth Ford, Liz McCullagh, James McErlane, Cian O'Donnell, Claire Durant, Ullrich Bartsch, Matt W. Jones, Carlos Muñoz-Neira, Alfie R. Wearn, John P. Grogan, Elizabeth J. Coulthard
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/e25d794abcbf4d9e9c248174ffc45c47