Výsledky vyhledávání - "McCoy, Connor"

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A surrogate function for one-dimensional phylogenetic likelihoods

Autor: Claywell, Brian C., Dinh, Vu C., McCoy, Connor O., Matsen IV, Frederick A.

Phylogenetics has seen an steady increase in substitution model complexity, which requires increasing amounts of computational power to compute likelihoods. This model complexity motivates strategies to approximate the likelihood functions for branch

Externí odkaz: http://arxiv.org/abs/1706.00659

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Quantifying evolutionary constraints on B cell affinity maturation

Autor: McCoy, Connor O., Bedford, Trevor, Minin, Vladimir N., Bradley, Philip, Robins, Harlan, Matsen IV, Frederick A.

The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through high-throughput seq

Externí odkaz: http://arxiv.org/abs/1403.3066

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Abundance-weighted phylogenetic diversity measures distinguish microbial community states and are robust to sampling depth

Autor: McCoy, Connor O., Matsen IV, Frederick A.

In microbial ecology studies, the most commonly used ways of investigating alpha (within-sample) diversity are either to apply count-only measures such as Simpson's index to Operational Taxonomic Unit (OTU) groupings, or to use classical phylogenetic

Externí odkaz: http://arxiv.org/abs/1305.0306

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Minimizing the average distance to a closest leaf in a phylogenetic tree

Autor: Matsen, Frederick A., Gallagher, Aaron, McCoy, Connor

When performing an analysis on a collection of molecular sequences, it can be convenient to reduce the number of sequences under consideration while maintaining some characteristic of a larger collection of sequences. For example, one may wish to sel

Externí odkaz: http://arxiv.org/abs/1205.6867

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