High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours

Autor: Davies Nigel P, Wilson Martin, Brundler Marie-Anne, McConville Carmel, Grundy Richard G, Peet Andrew C

Publikováno v: Molecular Cancer, Vol 8, Iss 1, p 6 (2009)

Abstract Background Brain and nervous system tumours are the most common solid cancers in children. Molecular characterisation of these tumours is important for providing novel biomarkers of disease and identifying molecular pathways which may provid

Externí odkaz: https://doaj.org/article/98e07532ba4c4da6919d4ed1c580fd76

Macrophage-derived IL-1? and TNF-? regulate arginine metabolism in neuroblastoma

Autor: Fultang, Livingstone, Gamble, Laura D, Gneo, Luciana, Berry, Andrea M, Egan, Sharon A., De Bie, Fenna, Yogev, Orli, Eden, Georgina L., Booth, Sarah, Brownhill, Samantha, Vardon, Ashley, McConville, Carmel M, Cheng, Paul N, Norris, Murray D, Etchevers, Heather C, Murray, Jayne, Ziegler, David S, Chesler, Louis, Schmidt, Ronny, Burchill, Susan A, Haber, Michelle, De Santo, Carmela, Mussai, Francis, Gamble, Laura D., Berry, Andrea M., McConville, Carmel M., Cheng, Paul N., Norris, Murray D., Etchevers, Heather C., Ziegler, David S., Burchill, Susan A.

© 2018 American Association for Cancer Research. Neuroblastoma is the most common childhood solid tumor, yet the prognosis for high-risk disease remains poor. We demonstrate here that arginase 2 (ARG2) drives neuroblastoma cell proliferation via reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::a1951bdaaa00d450b5e1280a02744440

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumour suppressor gene in neuroblastoma

Autor: Charlet, Jessica, Tomari, Ayumi, Dallosso, Anthony R, Szemes, Marianna, Kaselova, Martina, Curry, Tom J, Almutairi, Bader, Etchevers, Heather, McConville, Carmel, Malik, Karim, Brown, Keith

Publikováno v: Charlet, J, Tomari, A, Dallosso, A R, Szemes, M, Kaselova, M, Curry, T J, Almutairi, B, Etchevers, H, McConville, C, Malik, K & Brown, K 2017, ' Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumour suppressor gene in neuroblastoma ', Molecular Carcinogenesis, vol. 56, no. 4, pp. 1290–1301 . https://doi.org/10.1002/mc.22591

Neuroblastoma is a childhood cancer in which many children still have poor outcomes, emphasising the need to better understand its pathogenesis. Despite recent genome-wide mutation analyses, many primary neuroblastomas do not contain recognisable dri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2642::ff4797ecc766266d75c490d6351dc1ba
https://research-information.bris.ac.uk/en/publications/526466a5-4169-4105-894e-e20bfb74bd29

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.