Zobrazeno 1 - 10
of 599
pro vyhledávání: '"McColgan, P."'
Autor:
Nicholas S. Caron, Lauren M. Byrne, Fanny L. Lemarié, Jeffrey N. Bone, Amirah E.-E. Aly, Seunghyun Ko, Christine Anderson, Lorenzo L. Casal, Austin M. Hill, David J. Hawellek, Peter McColgan, Edward J. Wild, Blair R. Leavitt, Michael R. Hayden
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2024)
Abstract Background Therapeutic approaches aimed at lowering toxic mutant huntingtin (mHTT) levels in the brain can reverse disease phenotypes in animal models of Huntington's disease (HD) and are currently being evaluated in clinical trials. Sensiti
Externí odkaz:
https://doaj.org/article/89b2e043ae1a4ef094cfbb9512ed2741
Autor:
Doyon, Rene, Willott, C. J, Hutchings, John B., Sivaramakrishnan, Anand, Albert, Loic, Lafreniere, David, Rowlands, Neil, Vila, M. Begona, Martel, Andre R., LaMassa, Stephanie, Aldridge, David, Artigau, Etienne, Cameron, Peter, Chayer, Pierre, Cook, Neil J., Cooper, Rachel A., Darveau-Bernier, Antoine, Dupuis, Jean, Earnshaw, Colin, Espinoza, Nestor, Filippazzo, Joseph C., Fullerton, Alexander W., Gaudreau, Daniel, Gawlik, Roman, Goudfrooij, Paul, Haley, Craig, Kammerer, Jens, Kendall, David, Lambros, Scott D., Ignat, Luminita Ilinca, Maszkiewicz, Michael, McColgan, Ashley, Morishita, Takahiro, Ouellette, Nathalie N. -Q., Pacifici, Camilla, Philippi, Natasha, Radica, Michael, Ravindranath, Swara, Rowe, Jason, Roy, Arpita, Saad, Karl, Sohn, Sangmo Tony, Talens, Geert Jan, Thatte, Deepashri, Taylor, Joanna M., Vandal, Thomas, Volk, Kevin, Wander, Michel, Warner, Gerald, Zheng, Sheng-Hai, Zhou, Julia, Abraham, Roberto, Beaulieu, Mathilde, Benneke, Bjorn, Ferrarese, Laura, Johnstone, Doug, Kaltenegger, Lisa, Meyer, Michael R., Pipher, Judy L., Rameau, Julien, Rieke, Marcia, Salhi, Salma, Sawicki, Marcin
The Near-Infrared Imager and Slitless Spectrograph (NIRISS) is the science module of the Canadian-built Fine Guidance Sensor (FGS) onboard the James Webb Space Telescope (JWST). NIRISS has four observing modes: 1) broadband imaging featuring seven of
Externí odkaz:
http://arxiv.org/abs/2306.03277
Autor:
Alerie Guzman de la Fuente, Marie Dittmer, Elise J. Heesbeen, Nira de la Vega Gallardo, Jessica A. White, Andrew Young, Tiree McColgan, Amy Dashwood, Katie Mayne, Sonia Cabeza-Fernández, John Falconer, Francisco Javier Rodriguez-Baena, Christopher E. McMurran, Mohammed Inayatullah, Khalil S. Rawji, Robin J. M. Franklin, James Dooley, Adrian Liston, Rebecca J. Ingram, Vijay K. Tiwari, Rosana Penalva, Yvonne Dombrowski, Denise C. Fitzgerald
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Myelin regeneration (remyelination) is essential to prevent neurodegeneration in demyelinating diseases such as Multiple Sclerosis, however, its efficiency declines with age. Regulatory T cells (Treg) recently emerged as critical players in
Externí odkaz:
https://doaj.org/article/f70bb2debb2f424cb592cce6e9b75195
Autor:
Matthias Machacek, Elena Garcia-Montoya, Peter McColgan, Patricia Sanwald-Ducray, Norman Alan Mazer
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The concentrations of neurofilament light chain (NfL) in cerebrospinal fluid (CSF) and plasma have become key biomarkers of many neurodegenerative diseases, including Huntington's Disease (HD). However, the relationship between the dynamics of NfL co
Externí odkaz:
https://doaj.org/article/9e7cdeb91adf409f83d530e86d1089e6
Akademický článek
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Akademický článek
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Autor:
Angeliki Zarkali, Andrea I. Luppi, Emmanuel A. Stamatakis, Suzanne Reeves, Peter McColgan, Louise-Ann Leyland, Andrew J. Lees, Rimona S. Weil
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The examination of temporal dynamics in Parkinson’s-hallucinations reveals that the combination of neurochemistry and brain structure jointly shape functional brain dynamics leading to hallucinations.
Externí odkaz:
https://doaj.org/article/7e4dedb5efb44542b32ede5f408821d5
Akademický článek
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Autor:
Marc Fuchs, Clara Radulescu, Miao Tang, Arun Mahesh, Deborah Lavin, Syed Umbreen, James McKenna, Mark Smyth, Eilís McColgan, Zoltan Molnar, Chris Baxter, Timofey Skvortsov, Aditi Singh, Fiona Rogan, Julia Miskelly, Stephen Bridgett, Derek Fairley, David A. Simpson
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background The COVID-19 pandemic has highlighted the importance of whole genome sequencing (WGS) of SARS-CoV-2 to inform public health policy. By enabling definition of lineages it facilitates tracking of the global spread of the virus. The
Externí odkaz:
https://doaj.org/article/d0a26f61b2eb437880f7f489c8826b77
Autor:
Riley B. Brackin, Gail E. McColgan, Saitheja A. Pucha, Michael A. Kowalski, Hicham Drissi, Thanh N. Doan, Jay M. Patel
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 1013 (2023)
Traumatic joint injuries are common, leading to progressive tissue degeneration and the development of osteoarthritis. The post-traumatic joint experiences a pro-inflammatory milieu, initiating a subtle but deteriorative process in cartilage tissue.
Externí odkaz:
https://doaj.org/article/6413a437a29e41d5a659f73d540cd89e