Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma.

Autor: McGowan DR; Department of Oncology, University of Oxford, Oxford, United Kingdom; Radiation Physics and Protection, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Skwarski M; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Bradley KM; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Campo L; Department of Oncology, University of Oxford, Oxford, United Kingdom., Fenwick JD; Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom., Gleeson FV; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Green M; Department of Oncology, University of Oxford, Oxford, United Kingdom., Horne A; Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Maughan TS; Department of Oncology, University of Oxford, Oxford, United Kingdom., McCole MG; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Mohammed S; Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Muschel RJ; Department of Oncology, University of Oxford, Oxford, United Kingdom., Ng SM; Oncology Clinical Trials Office, Department of Oncology, University of Oxford, Oxford, United Kingdom., Panakis N; Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Prevo R; Department of Oncology, University of Oxford, Oxford, United Kingdom., Strauss VY; Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Stuart R; Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Tacconi EMC; Department of Oncology, University of Oxford, Oxford, United Kingdom., Vallis KA; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., McKenna WG; Department of Oncology, University of Oxford, Oxford, United Kingdom., Macpherson RE; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Higgins GS; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom. Electronic address: geoffrey.higgins@oncology.ox.ac.uk.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2019 May; Vol. 113, pp. 87-95. Date of Electronic Publication: 2019 Apr 13.