Zobrazeno 1 - 10
of 39
pro vyhledávání: '"McClure KF"'
Autor:
Barhoosh H; Department of Pharmaceutical Sciences, University of California, Irvine, California 92697, United States., Dixit A; Department of Pharmaceutical Sciences, University of California, Irvine, California 92697, United States., Cochrane WG; Department of Pharmaceutical Sciences, University of California, Irvine, California 92697, United States., Cavett V; Department of Pharmaceutical Sciences, University of California, Irvine, California 92697, United States., Prince RN; Initial Therapeutics, South San Francisco, California 94080, United States., Blair BO; Initial Therapeutics, South San Francisco, California 94080, United States., Ward FR; Initial Therapeutics, South San Francisco, California 94080, United States., McClure KF; Initial Therapeutics, South San Francisco, California 94080, United States., Patten PA; Initial Therapeutics, South San Francisco, California 94080, United States., Paulick MG; Initial Therapeutics, South San Francisco, California 94080, United States., Paegel BM; Department of Pharmaceutical Sciences, University of California, Irvine, California 92697, United States.; Departments of Chemistry & Biomedical Engineering, University of California, Irvine, California 92697, United States.
Publikováno v:
ACS central science [ACS Cent Sci] 2024 Oct 04; Vol. 10 (10), pp. 1960-1968. Date of Electronic Publication: 2024 Oct 04 (Print Publication: 2024).
Autor:
Aspnes GE; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Coffey SB; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Darout E; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Dechert-Schmitt AM; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Dullea RG; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Kamlet AS; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Limberakis C; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Londregan AT; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., McClure KF; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Menhaji-Klotz E; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Piotrowski DW; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA. Electronic address: david.w.piotrowski@comcast.net., Polivkova J; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Raymer B; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Ruggeri RB; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Salatto CT; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Tu M; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Wei L; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Xiao J; Pfizer Medicine Design, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Aug 15; Vol. 92, pp. 129394. Date of Electronic Publication: 2023 Jun 26.
Autor:
Gopalsamy A; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Aulabaugh AE; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Barakat A; Rare Diseases Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Beaumont KC; Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Cabral S; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Canterbury DP; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Casimiro-Garcia A; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Chang JS; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Chen MZ; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Choi C; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Dow RL; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Fadeyi OO; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Feng X; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., France SP; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Howard RM; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Janz JM; Rare Diseases Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Jasti J; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Jasuja R; Rare Diseases Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Jones LH; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., King-Ahmad A; Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Knee KM; Rare Diseases Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Kohrt JT; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Limberakis C; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Liras S; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Martinez CA; Medicinal Sciences, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., McClure KF; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Narayanan A; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Narula J; Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Novak JJ; Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., O'Connell TN; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Parikh MD; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Piotrowski DW; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Plotnikova O; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Robinson RP; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Sahasrabudhe PV; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Sharma R; Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Thuma BA; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Vasa D; Drug Product Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States., Wei L; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Wenzel AZ; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Withka JM; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Xiao J; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Yayla HG; Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Jan 14; Vol. 64 (1), pp. 326-342. Date of Electronic Publication: 2020 Dec 24.
Autor:
Liras S; Biogen Inc., 225 Binney Street, Cambridge, Massachusetts 02142, United States., Mcclure KF; Pinteon Therapeutics, 1188 Centre Street, Newton Centre, Massachusetts 02549, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Jun 14; Vol. 10 (7), pp. 1026-1032. Date of Electronic Publication: 2019 Jun 14 (Print Publication: 2019).
Autor:
Li W; Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Ward FR; Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA., McClure KF; Pfizer Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Chang ST; Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Montabana E; Molecular Biophysics and Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Liras S; Pfizer Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Dullea RG; Cardiovascular, Metabolic and Endocrine Disease Research Unit, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Cate JHD; Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA. jcate@lbl.gov.; Molecular Biophysics and Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. jcate@lbl.gov.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA. jcate@lbl.gov.
Publikováno v:
Nature structural & molecular biology [Nat Struct Mol Biol] 2019 Jun; Vol. 26 (6), pp. 501-509. Date of Electronic Publication: 2019 Jun 03.
Autor:
Londregan AT; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States. Electronic address: allyn.t.londregan@pfizer.com., Aspnes G; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Limberakis C; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Loria PM; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., McClure KF; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Petersen DN; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Raymer B; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Ruggeri RB; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Wei L; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Xiao J; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States., Piotrowski DW; Pfizer Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, United States.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Dec 15; Vol. 28 (23-24), pp. 3685-3688. Date of Electronic Publication: 2018 Oct 22.
Autor:
Londregan AT; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Wei L; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Xiao J; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Lintner NG; Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , California 94720 , United States., Petersen D; Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism , Pfizer Worldwide Research and Development , Groton , Connecticut 06340 , United States., Dullea RG; Internal Medicine Research Unit , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., McClure KF; Pfizer Medicinal Chemistry, Internal Medicine Research Unit , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., Bolt MW; Drug Safety Research & Development , Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States., Warmus JS; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Coffey SB; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Limberakis C; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Genovino J; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Thuma BA; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Hesp KD; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States., Aspnes GE; Pfizer Medicinal Chemistry, Internal Medicine Research Unit , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., Reidich B; Internal Medicine Research Unit , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., Salatto CT; Internal Medicine Research Unit , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., Chabot JR; Pfizer Pharmacokinetics, Dynamics and Metabolism Modeling and Simulation , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., Cate JHD; Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , California 94720 , United States.; QB3 Institute , University of California, Berkeley , Berkeley , California 94720 , United States.; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States.; Physical Biosciences Division , Lawrence Berkeley National Laboratory , Berkeley , California 94720 , United States., Liras S; Pfizer Medicinal Chemistry, Internal Medicine Research Unit , Pfizer Worldwide Research and Development , Cambridge , Massachusetts 02139 , United States., Piotrowski DW; Pfizer Medicinal Chemistry , Groton , Connecticut 06340 , United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Jul 12; Vol. 61 (13), pp. 5704-5718. Date of Electronic Publication: 2018 Jun 25.
Autor:
Rouet R, Thuma BA; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Roy MD; Pfizer Drug Safety R&D , Groton , Connecticut 06340 , United States., Lintner NG; Pfizer Medicine Design , Cambridge , Massachusetts 02139 , United States., Rubitski DM; Pfizer Drug Safety R&D , Groton , Connecticut 06340 , United States., Finley JE; Pfizer Drug Safety R&D , Groton , Connecticut 06340 , United States., Wisniewska HM; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Mendonsa R, Hirsh A, de Oñate L, Compte Barrón J, McLellan TJ; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Bellenger J; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Feng X; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Varghese A; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Chrunyk BA; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Borzilleri K; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Hesp KD; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Zhou K, Ma N, Tu M; Pfizer Medicine Design , Cambridge , Massachusetts 02139 , United States., Dullea R; Pfizer CVMET Biology , Cambridge , Massachusetts 02139 , United States., McClure KF; Pfizer Medicine Design , Cambridge , Massachusetts 02139 , United States., Wilson RC, Liras S; Pfizer Medicine Design , Cambridge , Massachusetts 02139 , United States., Mascitti V; Pfizer Medicine Design , Groton , Connecticut 06340 , United States., Doudna JA; MBIB Division , Lawrence Berkeley National Laboratory , Berkeley , California 94720 , United States.
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2018 May 30; Vol. 140 (21), pp. 6596-6603. Date of Electronic Publication: 2018 May 18.
Autor:
Lintner NG, McClure KF, Petersen D, Londregan AT, Piotrowski DW, Wei L, Xiao J, Bolt M, Loria PM, Maguire B, Geoghegan KF, Huang A, Rolph T, Liras S, Doudna JA, Dullea RG, Cate JHD
Publikováno v:
PLoS biology [PLoS Biol] 2018 Apr 17; Vol. 16 (4), pp. e1002628. Date of Electronic Publication: 2018 Apr 17 (Print Publication: 2018).
Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.
Autor:
McClure KF; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Piotrowski DW; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Petersen D; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Wei L; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Xiao J; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Londregan AT; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Kamlet AS; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Dechert-Schmitt AM; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Raymer B; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Ruggeri RB; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Canterbury D; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Limberakis C; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Liras S; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., DaSilva-Jardine P, Dullea RG; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Loria PM; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Reidich B; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Salatto CT; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Eng H; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Kimoto E; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Atkinson K; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., King-Ahmad A; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Scott D; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Beaumont K; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Chabot JR; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Bolt MW; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Maresca K; Department of Medicinal Chemistry, Pfizer Inc, 1 Portland Street, Cambridge, MA, 02139, USA., Dahl K; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden., Arakawa R; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden., Takano A; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden., Halldin C; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Dec 18; Vol. 56 (51), pp. 16218-16222. Date of Electronic Publication: 2017 Nov 24.