Zobrazeno 1 - 10
of 57
pro vyhledávání: '"McClure, Don B."'
Autor:
Lin, Ho-Shen a, *, Rampersaud, Ashraff A a, Beavers, Lisa S a, McClure, Don B a, Gardner, Anthony J a, Eacho, Patrick I a, Foxworthy, Patricia S a, Gadski, Robert A a
Publikováno v:
In Steroids 1999 64(10):735-741
Autor:
Lin, Ho-Shen a, *, Rampersaud, Ashraff A a, Richett, Michael E a, Harper, Richard W a, Beavers, Lisa S a, McClure, Don B a, Gardner, Anthony J a, Eacho, Patrick I a, Foxworthy, Patricia S a, Gadski, Robert A a
Publikováno v:
In Steroids 1999 64(3):217-227
Autor:
Shuang Luo, Steven H. Zuckerman, John F. Carpenter, Dotzlaf Joe Edward, Mcclure Don B, Deborah L. Fisher, Yue-Wei Qian, Xiliang Wang, Aimin Lin, Victor J. Chen, Mariam Ehsani, Rebecca R. Miles
Publikováno v:
Hybridoma. 26:155-161
Folypolyglutamate synthetase (FPGS) plays a critical role in the cellular retention of both folates and antifolates. Resistance to antifolates is in part related to changes in FPGS enzyme activity and levels of messenger RNA, or in some instances, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0cc26ae2d43744b5267a8d6de54362
https://doi.org/10.1089/hyb.2007.004
https://doi.org/10.1089/hyb.2007.004
Autor:
Jon A. Erickson, Lianshen Zhang, Marian Mosior, Jose Alfredo Martin, Mccarthy James R, Sheila P. Little, Xiyun Chai, Jingdan Hu, Wayne David Kohn, Shu-Hui Chen, John P. Mayer, Ana B. Bueno, Patrick C. May, Mcclure Don B, Leonard N. Boggs, Hsiu-Chiung Yang, Wu-Kuang Yeh, Patricia Gonzalez-DeWhitt
Publikováno v:
Journal of Neurochemistry. 91:1249-1259
β-amyloid peptides (Aβ) are produced by a sequential cleavage of amyloid precursor protein (APP) by β- and γ-secretases. The lack of Aβ production in beta-APP cleaving enzyme (BACE1)–/– mice suggests that BACE1 is the principal β-secretase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::883965d35eb8d98597ec548f5721a525
https://doi.org/10.1111/j.1471-4159.2004.02764.x
https://doi.org/10.1111/j.1471-4159.2004.02764.x
Autor:
Melvyn Baez, Lisa M. Churgay, Mcclure Don B, Leonard N. Boggs, Patrick C. May, Kimberly S. Fuson, Gerald W. Becker
Publikováno v:
Journal of Neurochemistry. 67:1324-1327
Clusterin is a secreted glycoprotein that is markedly induced in many disease states and after tissue injury. In the CNS, clusterin expression is elevated in neuropathological conditions such as Alzheimer's disease (AD), where it is found associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5ef7a8a615cef73e0e78fb78525847
https://doi.org/10.1046/j.1471-4159.1996.67031324.x
https://doi.org/10.1046/j.1471-4159.1996.67031324.x
Autor:
Dan L. Czilli, J.P Butler, John E. Hale, Sheila P. Little, Mcclure Don B, Weiying Li, L.K Simmons
Publikováno v:
Neuroscience. 95:1-4
Secreted isoforms of the beta-amyloid precursor protein potently enhance neuronal survival in cell cultures exposed to toxic amyloid beta peptide. Lowering of intracellular calcium levels to offset the increases in intraneuronal calcium caused by amy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be6014c11cd38c6d2dc3727d08ef4af
https://doi.org/10.1016/s0306-4522(99)00479-0
https://doi.org/10.1016/s0306-4522(99)00479-0
Autor:
Michael Enrico Richett, Ashraff A. Rampersaud, Robert Alan Gadski, Patricia S. Foxworthy, Anthony J Gardner, Patrick I. Eacho, Richard Waltz Harper, Ho-Shen Lin, Mcclure Don B, Lisa Selsam Beavers
Publikováno v:
Steroids. 64:217-227
4Alpha-(2-propenyl)-5alpha-cholestan-3alpha-ol (LY295427) was previously identified from a Chinese hamster ovary (CHO) cell-based low density lipoprotein receptor/luciferase (LDLR/Luc) assay to be a potent transcriptional activator of the LDL recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5614a8ed3bf5358518b533569e970616
https://doi.org/10.1016/s0039-128x(98)00083-x
https://doi.org/10.1016/s0039-128x(98)00083-x
Autor:
Ashraff A. Rampersaud, Mcclure Don B, Ho-Shen Lin, Lisa Selsam Beavers, Michael Enrico Richett, Robert Alan Gadski
Publikováno v:
Steroids. 63:202-207
4α-(2-Propenyl)-5α-cholestan-3α-ol (LY295427) was previously identified from a CHO cell-based assay to be a potent LDL receptor up-regulator and had demonstrated to be an effective agent in lowering plasma cholesterol levels in hypercholesterolemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37cc5e6f2135bb109a7387a34fdef80d
https://doi.org/10.1016/s0039-128x(98)00004-x
https://doi.org/10.1016/s0039-128x(98)00004-x
Autor:
N Bowling, Chris J. Vlahos, Robert Alan Gadski, T Schreyer, W F Matter, Mcclure Don B, P A Dawson
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 12, Pp 2586-2598 (1996)
LY295427, (3 alpha,4 alpha,5 alpha)-4-(2-propenylcholestan-3-ol), acts through an unknown mechanism to derepress the transcription of the low density lipoprotein (LDL) receptor in the presence of 25-hydroxycholesterol (25-OH chol). Preincubation with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45039e376145c6dc501bc7087e485e89
https://doi.org/10.1016/s0022-2275(20)37462-9
https://doi.org/10.1016/s0022-2275(20)37462-9
Publikováno v:
Journal of Biological Chemistry. 267:19710-19717
Human protein C (HPC) undergoes several post-translational modifications, including gamma-carboxylation, N-linked glycosylation, and internal proteolytic processing. We have utilized a recombinant human kidney cell line (293) secreting correctly modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99f97365088a26d71a6c4bf1246ab65
https://doi.org/10.1016/s0021-9258(18)41833-9
https://doi.org/10.1016/s0021-9258(18)41833-9