Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type and W/Wv mice.

Autor: McCloskey, K. D.^1,2 k.mccloskey@qub.ac.uk, Anderson, U. A.¹, Davidson, R. A.², Bayguinov, Y. R.³, Sanders, K. M.³, Ward, S. M.³

Publikováno v: British Journal of Pharmacology. Jan2009, Vol. 156 Issue 2, p273-283. 11p. 2 Diagrams, 5 Graphs.

Functional expression of KCNQ (Kv7) channels in guinea-pig bladder smooth muscle and their contribution to spontaneous activity

Autor: Anderson, U. A., Carson, C., Johnston, L., Joshi, S., Gurney, A. M., McCloskey, K. D.

Publikováno v: Anderson, U A, Carson, C, Johnston, L, Joshi, S, Gurney, A M & McCloskey, K D 2013, ' Functional expression of KCNQ (K v 7) channels in guinea-pig bladder smooth muscle and their contribution to spontaneous activity ', British Journal of Pharmacology, vol. 169, no. 6, pp. 1290-1304 . https://doi.org/10.1111/bph.12210

Background and Purpose: The aim of the study was to determine whether KCNQ channels are functionally expressed in bladder smooth muscle cells (SMC) and to investigate their physiological significance in bladder contractility. Experimental Approach: K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::c60b6644079fc46b1b14e24c82c9ab32
https://pure.qub.ac.uk/en/publications/functional-expression-of-kcnq-kv7-channels-in-guineapig-bladder-smooth-muscle-and-their-contribution-to-spontaneous-activity(1f508b52-795b-4c5d-99e7-3aae824ca82a).html

Ca(2+)-activated Cl(-) current in sheep lymphatic smooth muscle

Autor: Toland, H. M., McCloskey, K. D., Thornbury, Keith D., McHale, Noel G., Hollywood, Mark A.

Freshly dispersed sheep mesenteric lymphatic smooth muscle cells were studied at 37 degrees C using the perforated patch-clamp technique with Cs(+)- and K(+)-filled pipettes. Depolarizing steps evoked currents that consisted of L-type Ca(2+) [I(Ca(L)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2656::cd4ff9d945b68cf41e6dc4da97a62069
http://eprints.dkit.ie/203/

Specialised pacemaking cells in the rabbit urethra

Autor: Sergeant, Gerard P., Hollywood, Mark A., McCloskey, K. D., McHale, Noel G.

Collagenase dispersal of strips of rabbit urethra yielded, in addition to normal spindle-shaped smooth muscle cells, a small proportion of branched cells which resembled the interstitial cells of Cajal dispersed from canine colon. These were clearly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2656::a2dafd4fb89ebba5bd00f005fac07adf
http://eprints.dkit.ie/208/

Hyperpolarisation-activated inward current in isolated sheep mesenteric lymphatic smooth muscle

Autor: McCloskey, K. D., Toland, H. M., Hollywood, Mark A., Thornbury, Keith D., McHale, Noel G.

Freshly isolated sheep lymphatic smooth muscle cells were studied using the perforated patch-clamp technique. Hyperpolarisation with constant-current pulses caused a time-dependent rectification evident as a depolarising 'sag' followed by an anode-br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2656::b8bc8346e2e0ebaf88f228c28d51fb07
http://eprints.dkit.ie/209/