Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches.

Autor: McCabe, Niamh H.¹ (AUTHOR) nmccabe17@qub.ac.uk, Stevenson, Leanne¹ (AUTHOR) l.stevenson@qub.ac.uk, Scanlon, Enya¹ (AUTHOR) e.scanlon@qub.ac.uk, Douglas, Rosalie¹ (AUTHOR) rdouglas01@qub.ac.uk, Kennedy, Susanna¹ (AUTHOR) skennedy2014@qub.ac.uk, Keminer, Oliver^2,3 (AUTHOR) oliver.keminer@itmp.fraunhofer.de, Windshügel, Björn^2,3 (AUTHOR) bjoern.windshuegel@itmp.fraunhofer.de, Zisterer, Daniela⁴ (AUTHOR) dzistrer@tcd.ie, Kennedy, Richard D.⁵ (AUTHOR) richard.kennedy@almacgroup.com, Blayney, Jaine K.¹ (AUTHOR) j.blayney@qub.ac.uk, Turkington, Richard C.¹ (AUTHOR) r.turkington@qub.ac.uk

Publikováno v: Cancers. Aug2022, Vol. 14 Issue 15, p3726-3726. 18p.

Glucose transporter 1 expression as a marker of prognosis in oesophageal adenocarcinoma

Autor: Blayney, Jaine K., Cairns, Lauren, Li, Gerald, McCabe, Niamh, Stevenson, Leanne, Peters, Christopher J., Reid, Nathan B., Spence, Veronica J., Chisambo, Chintapuza, McManus, Damian, James, Jacqueline, McQuaid, Stephen, Craig, Stephanie, Arthur, Kenneth, McArt, Darragh, Ong, Chin-Ann J., Lao-Sirieix, Pierre, Hamilton, Peter, Salto-Tellez, Manuel, Eatock, Martin, Coleman, Helen G., Fitzgerald, Rebecca C., Kennedy, Richard D., Turkington, Richard C.

Publikováno v: Oncotarget
Blayney, J K, Cairns, L, Li, G, McCabe, N, Stevenson, L, Peters, C J, Reid, N B, Spence, V J, Chisambo, C, McManus, D, James, J, McQuaid, S, Craig, S, Arthur, K, McArt, D, Ong, C-A J, Lao-Sirieix, P, Hamilton, P, Salto-Tellez, M, Eatock, M, Coleman, H G, Fitzgerald, R C, Kennedy, R D & Turkington, R C 2018, ' Glucose Transporter 1 Expression as a Marker of Prognosis in Oesophageal Adenocarcinoma ', Oncotarget . https://doi.org/10.18632/oncotarget.24906

Background: The current TNM staging system for oesophageal adenocarcinoma (OAC) has limited ability to stratify patients and inform clinical management following neo-adjuvant chemotherapy and surgery.Patients and Methods: Transcriptional profiling of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b281de900af2c7a4bacc35cc38483fbb
http://europepmc.org/articles/PMC5915089

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Targeting Survivin to overcome cisplatin resistance in oesophageal adenocarcinoma

Autor: Douglas, Rosalie, Stevenson, Leanne, Santos, Ralph, Cairns, Lauren, McCabe, Niamh, Kennedy, Richard, Blayney, Jaine, Turkington, Richard

Publikováno v: Douglas, R, Stevenson, L, Santos, R, Cairns, L, McCabe, N, Kennedy, R, Blayney, J & Turkington, R 2019, ' Targeting Survivin to overcome cisplatin resistance in oesophageal adenocarcinoma ', Journal of Clinical Oncology .

Background:The incidence of Oesophageal Adenocarcinoma (OAC) has risen in the western world but response rates to chemotherapy are low and survival is poor. Increased molecular under-standing is needed to develop novel treatment.Methods:Transcription

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::ccbbc65697f67003d608d60200a627b8
https://pure.qub.ac.uk/en/publications/targeting-survivin-to-overcome-cisplatin-resistance-in-oesophageal-adenocarcinoma(b5b76711-31d9-4439-99bb-8966c4cd7502).html

A novel and dedicated multidisciplinary service to manage breech presentation at term; 3 years of experience in a tertiary care maternity unit.

Autor: Gargan, Phyl, Simpson, Jacquie, McCabe, Niamh, Hickland, Patrick, Costa, Janitha

Publikováno v: Journal of Maternal-Fetal & Neonatal Medicine; Nov2018, Vol. 31 Issue 22, p3002-3008, 7p