Small synthetic ligands of the cholecystokinin-B/gastrin receptor can mimic the function of endogenous peptide hormones

Autor: Beinborn, M., Chen, C., DeMeo, L., McBride, E. W., Kopin, A. S.

Publikováno v: The Yale Journal of Biology and Medicine

The gastric cholecystokinin-B/gastrin receptor (CCK-BR) is a key regulator of enterochromaffin-like cell function and proliferation. Over the last decade, a number of small non-peptide CCK-BR "antagonists" have been discovered. Here, we demonstrate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aaec071b7c4978b039a4556d5a197725
http://europepmc.org/articles/PMC2578980

The secretin gene: evolutionary history, alternative splicing, and developmental regulation.

Autor: Kopin, A S, Wheeler, M B, Nishitani, J, McBride, E W, Chang, T M, Chey, W Y, Leiter, A B

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; June 1991, Vol. 88 Issue: 12 p5335-5339, 5p

Expression cloning and characterization of the canine parietal cell gastrin receptor.

Autor: Kopin, A S, Lee, Y M, McBride, E W, Miller, L J, Lu, M, Lin, H Y, Kolakowski, L F, Beinborn, M

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; April 1992, Vol. 89 Issue: 8 p3605-3609, 5p

CCK receptor polymorphisms: an illustration of emerging themes in pharmacogenomics.

Autor: Kopin AS; Department of Medicine and the GRASP Digestive Disease Center, Tupper Research Institute, New England Medical Center, 750 Washington Street, Boston, MA 02111, USA. akopin@msn.com, McBride EW, Schaffer K, Beinborn M

Publikováno v: Trends in pharmacological sciences [Trends Pharmacol Sci] 2000 Sep; Vol. 21 (9), pp. 346-53.

The cholecystokinin-A receptor mediates inhibition of food intake yet is not essential for the maintenance of body weight.

Autor: Kopin AS; Department of Medicine, GRASP Digestive Disease Center, Tupper Research Institute, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA. alan.kopin@es.nemc.org, Mathes WF, McBride EW, Nguyen M, Al-Haider W, Schmitz F, Bonner-Weir S, Kanarek R, Beinborn M

Publikováno v: The Journal of clinical investigation [J Clin Invest] 1999 Feb; Vol. 103 (3), pp. 383-91.