The Role of Antibody Polyspecificity and Lipid Reactivity in Binding of Broadly Neutralizing Anti-HIV-1 Envelope Human Monoclonal Antibodies 2F5 and 4E10 to Glycoprotein 41 Membrane Proximal Envelope Epitopes1

Autor: Alam, S. Munir, McAdams, Mildred, Boren, David, Rak, Michael, Scearce, Richard M., Gao, Feng, Camacho, Zenaido T., Gewirth, Daniel, Kelsoe, Garnett, Chen, Pojen, Haynes, Barton F.

Two neutralizing human mAbs, 2F5 and 4E10, that react with the HIV-1 envelope gp41 membrane proximal region are also polyspecific autoantibodies that bind to anionic phospholipids. To determine the autoantibody nature of these Abs, we have compared t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1fed363802a2826b6a53f199375f817
https://europepmc.org/articles/PMC2262928/

No direct correlation between serum antiacetylcholine receptor antibody levels and clinical state of individual patients with myasthenia gravis.

Autor: Roses, Allen D., Olanow, C. Warren, McAdams, Mildred W., Lane, Russell J. M.

Publikováno v: Neurology; Feb1981, Vol. 31 Issue 2, p220-224, 5p

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.

Autor: Alam SM; Department of Medicine, Duke Human Vaccine Institute, Duke University School of Medicine, RP1 Circuit Drive, Durham, NC 27710, USA. alam0004@mc.duke.edu, McAdams M, Boren D, Rak M, Scearce RM, Gao F, Camacho ZT, Gewirth D, Kelsoe G, Chen P, Haynes BF

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2007 Apr 01; Vol. 178 (7), pp. 4424-35.