Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer

Autor: A. Pintus, Francesco Tanda, Antonella Manca, S. Tore, Salvatore Dessole, Giuseppe Palmieri, Antonio Cossu, Mc Sini, Rosella Muresu, C. Loddo, Marina Pisano, P. Baldinu

Publikováno v: European journal of cancer (1990) 38 (2002): 1802–1809. doi:10.1016/S0959-8049(02)00152-1
info:cnr-pdr/source/autori:Muresu, R.; Sini, M. C.; Cossu, A.; Tore, S.; Baldinu, P.; Manca, A.; Pisano, M.; Loddo, C.; Dessole, S.; Pintus, A.; Tanda, F.; Palmieri, G./titolo:Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer/doi:10.1016%2FS0959-8049(02)00152-1/rivista:European journal of cancer (1990)/anno:2002/pagina_da:1802/pagina_a:1809/intervallo_pagine:1802–1809/volume:38

Defective DNA mismatch repair and nonfunctional mechanisms controlling the proper progression of the cell cycle have been proposed as being responsible for the genomic instability and accumulation of karyotypic alterations in endometrial cancer (EC).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c04f7fce9a29bab7269cc631a9b926
https://pubmed.ncbi.nlm.nih.gov/12175698

Multiple Primary Melanomas from Same Patients Present Discrepant Somatic Alterations in Main Candidate Genes

Autor: Fabrizio Ayala, Mc Sini, Corrado Rubino, Antonio Cossu, D. Massi, P.A. Ascierto, Amelia Lissia, V. De Giorgi, Maria Colombino, Giovannella Palmieri

Publikováno v: Annals of Oncology. 23:ix364

Background A series of patients with multiple primary melanoma (MPM) were screened for the involvement of the key-regulator genes in susceptibility (CDKN2A) and pathogenesis (BRAF, cKIT, CyclinD1) of such a disease. Methods Genomic DNA from periphera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2547a627e5feb6a568eda3e05cacc125
https://doi.org/10.1016/s0923-7534(20)33714-5

Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian population.

Autor: Sini MC; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy., Doro MG; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy., Frogheri L; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy., Zinellu A; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Paliogiannis P; Department of Medicine, Surgery and Pharmacy, University of Sassari, Traversa La Crucca 3, 07100, Sassari, Italy., Porcu A; Department of Medicine, Surgery and Pharmacy, University of Sassari, Traversa La Crucca 3, 07100, Sassari, Italy., Scognamillo F; Department of Medicine, Surgery and Pharmacy, University of Sassari, Traversa La Crucca 3, 07100, Sassari, Italy., Delogu D; Department of Medicine, Surgery and Pharmacy, University of Sassari, Traversa La Crucca 3, 07100, Sassari, Italy., Santeufemia DA; Oncology, Civil Hospital, Alghero, Italy., Persico I; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy., Palomba G; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy., Maestrale GB; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy., Cossu A; Department of Medicine, Surgery and Pharmacy, University of Sassari, Traversa La Crucca 3, 07100, Sassari, Italy., Palmieri G; Unit of Cancer Genetics, Institute of Genetic Biomedical Research (IRGB), National Research Council (CNR), Sassari, Italy. gpalmieri@yahoo.com.; Immuno-Oncology & Targeted Cancer Biotherapies, University of Sassari, Sassari, Italy. gpalmieri@yahoo.com.

Publikováno v: Journal of translational medicine [J Transl Med] 2024 Jan 27; Vol. 22 (1), pp. 108. Date of Electronic Publication: 2024 Jan 27.

Mammary-like adenocarcinoma of the vulva: a rare case report with next generation sequencing.

Autor: Lobrano R; Unit of Anatomic Pathology and Histology, University Hospital of Sassari (A.O.U. SS), Sassari, Italy., Manca A; Unit of Anatomic Pathology and Histology, University Hospital of Sassari (A.O.U. SS), Sassari, Italy., Sini MC; Institute of Genetic and Biomolecular Research (IRGB), National Research Council (CNR), Sassari, Italy., Palmieri G; Institute of Genetic and Biomolecular Research (IRGB), National Research Council (CNR), Sassari, Italy.; Department of Biomedical Sciences, Sassari, Italy., Petrillo M; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy., Cossu A; Unit of Anatomic Pathology and Histology, University Hospital of Sassari (A.O.U. SS), Sassari, Italy.; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy., Paliogiannis P; Unit of Anatomic Pathology and Histology, University Hospital of Sassari (A.O.U. SS), Sassari, Italy.; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.

Publikováno v: Pathologica [Pathologica] 2023 Apr; Vol. 115 (2), pp. 101-106.

Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy.

Autor: Anichini A; Human Tumors Immunobiology Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy. andrea.anichini@istitutotumori.mi.it., Molla A; Human Tumors Immunobiology Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., Nicolini G; Human Tumors Immunobiology Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., Perotti VE; Human Tumors Immunobiology Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., Sgambelluri F; Human Tumors Immunobiology Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., Covre A; Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy.; University of Siena, Siena, Italy., Fazio C; Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy., Lofiego MF; Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy., Di Giacomo AM; Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy.; University of Siena, Siena, Italy., Coral S; Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy., Manca A; Unit of Cancer Genetics, National Research Council (CNR), Sassari, Italy., Sini MC; Unit of Cancer Genetics, National Research Council (CNR), Sassari, Italy., Pisano M; Unit of Cancer Genetics, National Research Council (CNR), Sassari, Italy., Noviello T; Department of Electrical Engineering and Information Technology (DIETI), University of Naples 'Federico II', Naples, Italy.; BIOGEM Institute of Molecular Biology and Genetics, Ariano Irpino, Italy., Caruso F; Department of Electrical Engineering and Information Technology (DIETI), University of Naples 'Federico II', Naples, Italy.; BIOGEM Institute of Molecular Biology and Genetics, Ariano Irpino, Italy., Brich S; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Pruneri G; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; University of Milan, School of Medicine, Milan, Italy., Maurichi A; Melanoma and Sarcoma Unit, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Santinami M; Melanoma and Sarcoma Unit, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Ceccarelli M; Department of Electrical Engineering and Information Technology (DIETI), University of Naples 'Federico II', Naples, Italy.; BIOGEM Institute of Molecular Biology and Genetics, Ariano Irpino, Italy., Palmieri G; Unit of Cancer Genetics, National Research Council (CNR), Sassari, Italy.; University of Sassari, Sassari, Italy., Maio M; Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy.; University of Siena, Siena, Italy., Mortarini R; Human Tumors Immunobiology Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Nov 17; Vol. 41 (1), pp. 325. Date of Electronic Publication: 2022 Nov 17.