Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Mc, Connelly"'
Publikováno v:
Europe PubMed Central
The pathways of 2',3'-dideoxyadenosine (ddAdo) metabolism, a selective inhibitor of the replication of human immunodeficiency virus, were investigated with use of the human T-lymphoid cell line CCRF-CEM which is deficient in either deoxycytidine kina
Autor:
Carrillo AK; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States., Kadayat TM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0509, United States., Hwang JY; Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Daejeon, KR 34114, United States., Chen Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0509, United States., Zhu F; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States., Holbrook G; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States., Gillingwater K; Department of Medical Parasitology & Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstrasse 2, Allschwil 4123, Switzerland., Connelly MC; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States., Yang L; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States., Kaiser M; Department of Medical Parasitology & Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstrasse 2, Allschwil 4123, Switzerland.; Faculty of Science, University of Basel, Petersplatz 1, Basel 4003, Switzerland., Guy RK; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0509, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Mar 14; Vol. 67 (5), pp. 3437-3447. Date of Electronic Publication: 2024 Feb 16.
Autor:
Mathew B; Drug Discovery Division, Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA., Snowden TS; Department of Chemistry and Biochemistry, The University of Alabama, 250 Hackberry Lane, Tuscaloosa, AL 35487, USA., Connelly MC; Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mailstop 1000, Memphis, TN 38105-3678, USA., Guy RK; The University of Kentucky College of Pharmacy, 214H BioPharm Complex, Lexington, KY 40536-0596, USA., Reynolds RC; Division of Hematology and Oncology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: rcr12lkt@uab.edu.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Jul 01; Vol. 28 (12), pp. 2136-2142. Date of Electronic Publication: 2018 May 10.
Autor:
Hammill JT; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Scott DC; Howard Hughes Medical Institute , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.; Department of Structural Biology , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Min J; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Connelly MC; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Holbrook G; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Zhu F; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Matheny A; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Yang L; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Singh B; Department of Surgery, Laboratory of Epithelial Cancer Biology , Memorial Sloan Kettering Cancer Center , New York , New York 10065 United States., Schulman BA; Howard Hughes Medical Institute , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.; Department of Structural Biology , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Guy RK; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Apr 12; Vol. 61 (7), pp. 2680-2693. Date of Electronic Publication: 2018 Mar 26.
Autor:
Hammill JT; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Bhasin D; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Scott DC; Howard Hughes Medical Institute , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.; Department of Structural Biology , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Min J; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Chen Y; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Lu Y; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Yang L; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Kim HS; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Connelly MC; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Hammill C; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Holbrook G; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Jeffries C; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Singh B; Department of Surgery, Laboratory of Epithelial Cancer Biology , Memorial Sloan Kettering Cancer Center , New York , New York , 10065 United States., Schulman BA; Howard Hughes Medical Institute , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.; Department of Structural Biology , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States., Guy RK; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Apr 12; Vol. 61 (7), pp. 2694-2706. Date of Electronic Publication: 2018 Mar 26.
Autor:
Mathew B; Drug Discovery Division, Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA., Hobrath JV; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Connelly MC; Department of Chemical Biology & Therapeutics, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mailstop 1000, Memphis, TN 38105-3678 USA., Guy RK; The University of Kentucky College of Pharmacy, 214H BioPharm Complex, Lexington, KY 40536-0596, USA., Reynolds RC; Division of Hematology & Oncology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
Publikováno v:
Future medicinal chemistry [Future Med Chem] 2018 Apr 01; Vol. 10 (7), pp. 743-753. Date of Electronic Publication: 2018 Apr 19.
Autor:
Mathew B; Drug Discovery Division, Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA., Hobrath JV; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Connelly MC; Department of Chemical Biology & Therapeutics, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mailstop 1000, Memphis, TN 38105-3678, USA., Guy RK; The University of Kentucky College of Pharmacy, 214H BioPharm Complex, Lexington, KY 40536-0596, USA., Reynolds RC; Division of Hematology and Oncology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
Publikováno v:
The open medicinal chemistry journal [Open Med Chem J] 2018 Jan 31; Vol. 12, pp. 1-12. Date of Electronic Publication: 2018 Jan 31 (Print Publication: 2018).
Autor:
Foulk B; Janssen Research & Development, LLC, Spring House, PA, USA., Schaffer M; Janssen Research & Development, LLC, Spring House, PA, USA., Gross S; Menarini Silicon Biosystems, Huntingdon Valley, PA, USA., Rao C; Janssen Research & Development, LLC, Spring House, PA, USA., Smirnov D; Janssen Research & Development, LLC, Spring House, PA, USA., Connelly MC; Menarini Silicon Biosystems, Huntingdon Valley, PA, USA., Chaturvedi S; Janssen Research & Development, LLC, Spring House, PA, USA., Reddy M; Janssen Research & Development, LLC, Spring House, PA, USA., Brittingham G; Janssen Research & Development, LLC, Spring House, PA, USA., Mata M; Janssen Research & Development, LLC, Spring House, PA, USA., Repollet M; Menarini Silicon Biosystems, Huntingdon Valley, PA, USA., Rojas C; Menarini Silicon Biosystems, Huntingdon Valley, PA, USA., Auclair D; Multiple Myeloma Research Foundation, Norwalk, CT, USA., DeRome M; Multiple Myeloma Research Foundation, Norwalk, CT, USA., Weiss B; Abramson Cancer Center and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sasser AK; Janssen Research & Development, LLC, Spring House, PA, USA.
Publikováno v:
British journal of haematology [Br J Haematol] 2018 Jan; Vol. 180 (1), pp. 71-81. Date of Electronic Publication: 2017 Nov 05.
Autor:
Mathew B; Drug Discovery Division, Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA., Hobrath JV; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Connelly MC; Department of Chemical Biology & Therapeutics, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mailstop 1000, Memphis, TN 38105-3678, USA., Kiplin Guy R; The University of Kentucky College of Pharmacy, 214H BioPharm Complex, Lexington, KY 40536-0596, USA., Reynolds RC; Division of Hematology and Oncology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: rcr12lkt@uab.edu.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Oct 15; Vol. 27 (20), pp. 4614-4621. Date of Electronic Publication: 2017 Sep 13.
Autor:
Muse ED; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA., Kramer ER; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA., Wang H; Ortho Clinical Diagnostics, Raritin, NJ, USA., Barrett P; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA., Parviz F; Janssen Research & Development, LLC, Huntingdon Valley, PA, USA., Novotny MA; J. Craig Venter Institute, La Jolla, CA, USA., Lasken RS; J. Craig Venter Institute, La Jolla, CA, USA., Jatkoe TA; Ortho Clinical Diagnostics, Raritin, NJ, USA., Oliveira G; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA., Peng H; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA., Lu J; Biological Dynamics, San Diego, CA, USA., Connelly MC; Janssen Research & Development, LLC, Huntingdon Valley, PA, USA., Schilling K; Ortho Clinical Diagnostics, Rochester, NY, USA., Rao C; Janssen Research & Development, LLC, Huntingdon Valley, PA, USA., Torkamani A; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA., Topol EJ; The Scripps Translational Science Institute, The Scripps Research Institute, Scripps Health, La Jolla, USA. etopol@scripps.edu.
Publikováno v:
Scientific reports [Sci Rep] 2017 Sep 25; Vol. 7 (1), pp. 12268. Date of Electronic Publication: 2017 Sep 25.