Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability-high metastatic colorectal cancer treated with immune checkpoint inhibitors

Autor: Manca, Paolo, Corti, Francesca, Intini, Rossana, Mazzoli, Giacomo, Miceli, Rosalba, Germani, Marco Maria, Bergamo, Francesca, Ambrosini, Margherita, Cristarella, Eleonora, Cerantola, Riccardo, Boccaccio, Chiara, Ricagno, Gianmarco, Ghelardi, Filippo, Randon, Giovanni, Leoncini, Giuseppe, Milione, Massimo, Fassan, Matteo, Cremolini, Chiara, Lonardi, Sara, Pietrantonio, Filippo

Publikováno v: In European Journal of Cancer July 2023 187:15-24

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Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers

Autor: Fucà, Giovanni, Cohen, Romain, Lonardi, Sara, Shitara, Kohei, Elez, Elena, Fakih, Marwan, Chao, Joseph, Klempner, Samuel J., Emmett, Matthew, Jayachandran, Priya, Bergamo, Francesca, García, Marc Díez, Mazzoli, Giacomo, Provenzano, Leonardo, Colle, Raphael, Svrcek, Magali, Ambrosini, Margherita, Randon, Giovanni, Shah, Aakash Tushar, Salati, Massimiliano, Fenocchio, Elisabetta, Salvatore, Lisa, Chida, Keigo, Kawazoe, Akihito, Conca, Veronica, Curigliano, Giuseppe, Corti, Francesca, Cremolini, Chiara, Overman, Michael, Andre, Thierry, Pietrantonio, Filippo, Universitat Autònoma de Barcelona

Publikováno v: Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 2022, 10 (2), pp.e004001. ⟨10.1136/jitc-2021-004001⟩
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

BackgroundDespite unprecedented benefit from immune checkpoint inhibitors (ICIs) in patients with mismatch repair deficient (dMMR)/microsatellite instability high (MSI-H) advanced gastrointestinal cancers, a relevant proportion of patients shows prim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af53310f509789866de93ad7dda90566
https://pubmed.ncbi.nlm.nih.gov/35110358