Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mazhar Ajaz"'
Autor:
Kamalram Thippu Jayaprakash, MSc, MRCP (UK), FRCR, MD, Mohammad Hussein, BSc, MSc, PhD, Richard Shaffer, MRCP (UK), FRCR, Agnieszka Michael, PhD, Andrew Nisbet, MSc, PhD, Mazhar Ajaz, MRCP (UK), FRCR, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 2, Pp 100622- (2021)
Purpose: The scope of radiation therapy is limited in melanoma. Using in vitro melanoma models, we investigated a Notch signaling inhibitor as a radiosensitizer to explore its potential to improve the efficacy of radiation therapy to widen the clinic
Externí odkaz:
https://doaj.org/article/26e6affc573b4ff7bcca4613424babb2
Autor:
Kamalram Thippu Jayaprakash, Denis Mostafa, Mohammad Hussein, Richard Shaffer, Agnieszka Michael, Mazhar Ajaz, Andrew Nisbet
Publikováno v:
Applied Sciences, Vol 12, Iss 3, p 1456 (2022)
We designed and developed a multiwell tissue culture plate irradiation setup, and intensity modulated radiotherapy plans were generated for 96-, 24-, and 6-well tissue culture plates. We demonstrated concordance between planned and measured/imaged ra
Externí odkaz:
https://doaj.org/article/6153af5637c94edb9c471016e341f794
Publikováno v:
Journal of Contemporary Brachytherapy, Vol 8, Iss 6, Pp 557-565 (2016)
Brachytherapy is an essential component of the treatment of locally advanced cervical cancers. It enables the dose to the tumor to be boosted whilst allowing relative sparing of the normal tissues. Traditionally, cervical brachytherapy was prescribed
Externí odkaz:
https://doaj.org/article/b4049597361d48c2a33c6063db25db5b
Autor:
Nicholas C. Turner, David Cunningham, Sanjay Popat, Ian Chau, David Watkins, Angela Gillbanks, Katherine Sumpter, Mazhar Ajaz, Stephen R.D. Johnston, Anne Thomas, Sue Chua, Gina Brown, Amanda Swain, Kerry Fenwick, Jian Ning, James Campbell, Ros Cutts, Claire Rooney, Catherine Geh, Neil R. Smith, Elaine Kilgour, Clare Peckitt, Noelia Tarazona, Maria Teresa Herrera-Abreu, Irina S. Babina, Elizabeth Smyth, Alex Pearson
Investigation of PI3K-AKT signalling in FGFR amplified cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1e72dc3b7fd6d5009bb87f785c41d6
https://doi.org/10.1158/2159-8290.22531236.v1
https://doi.org/10.1158/2159-8290.22531236.v1
Autor:
Nicholas C. Turner, David Cunningham, Sanjay Popat, Ian Chau, David Watkins, Angela Gillbanks, Katherine Sumpter, Mazhar Ajaz, Stephen R.D. Johnston, Anne Thomas, Sue Chua, Gina Brown, Amanda Swain, Kerry Fenwick, Jian Ning, James Campbell, Ros Cutts, Claire Rooney, Catherine Geh, Neil R. Smith, Elaine Kilgour, Clare Peckitt, Noelia Tarazona, Maria Teresa Herrera-Abreu, Irina S. Babina, Elizabeth Smyth, Alex Pearson
Supplementary Table 1. Expression of estrogen receptor regulated genes in patient 207 was determined using Nanostring. Data was normalized as described in the Online Methods and is presented as the Log2 ratio. Supplementary Table 2. A list of cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea98c916553ba491969f0f1c32b3557
https://doi.org/10.1158/2159-8290.22531227.v1
https://doi.org/10.1158/2159-8290.22531227.v1
Autor:
Nicholas C. Turner, David Cunningham, Sanjay Popat, Ian Chau, David Watkins, Angela Gillbanks, Katherine Sumpter, Mazhar Ajaz, Stephen R.D. Johnston, Anne Thomas, Sue Chua, Gina Brown, Amanda Swain, Kerry Fenwick, Jian Ning, James Campbell, Ros Cutts, Claire Rooney, Catherine Geh, Neil R. Smith, Elaine Kilgour, Clare Peckitt, Noelia Tarazona, Maria Teresa Herrera-Abreu, Irina S. Babina, Elizabeth Smyth, Alex Pearson
Results of parallel siRNA screens in FGFR driven cell lines with analysis of ERK and AKT phosphorylation in and panel of FGFR driven cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7edb390ff5909a5ffe507d97d17825
https://doi.org/10.1158/2159-8290.22531239.v1
https://doi.org/10.1158/2159-8290.22531239.v1
Autor:
Nicholas C. Turner, David Cunningham, Sanjay Popat, Ian Chau, David Watkins, Angela Gillbanks, Katherine Sumpter, Mazhar Ajaz, Stephen R.D. Johnston, Anne Thomas, Sue Chua, Gina Brown, Amanda Swain, Kerry Fenwick, Jian Ning, James Campbell, Ros Cutts, Claire Rooney, Catherine Geh, Neil R. Smith, Elaine Kilgour, Clare Peckitt, Noelia Tarazona, Maria Teresa Herrera-Abreu, Irina S. Babina, Elizabeth Smyth, Alex Pearson
Clinical activity of FGFR inhibitor AZD4547 in FGFR amplified breast and gastric cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da36d24cecb69eb5fdcedc49c6d21434
https://doi.org/10.1158/2159-8290.22531248.v1
https://doi.org/10.1158/2159-8290.22531248.v1
Autor:
Nicholas C. Turner, David Cunningham, Sanjay Popat, Ian Chau, David Watkins, Angela Gillbanks, Katherine Sumpter, Mazhar Ajaz, Stephen R.D. Johnston, Anne Thomas, Sue Chua, Gina Brown, Amanda Swain, Kerry Fenwick, Jian Ning, James Campbell, Ros Cutts, Claire Rooney, Catherine Geh, Neil R. Smith, Elaine Kilgour, Clare Peckitt, Noelia Tarazona, Maria Teresa Herrera-Abreu, Irina S. Babina, Elizabeth Smyth, Alex Pearson
High-level FGFR2 amplified cell lines are highly sensitive to FGFR inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08279a8f98a5f790780a9c454bf283f7
https://doi.org/10.1158/2159-8290.22531242
https://doi.org/10.1158/2159-8290.22531242
Autor:
Nicholas C. Turner, David Cunningham, Sanjay Popat, Ian Chau, David Watkins, Angela Gillbanks, Katherine Sumpter, Mazhar Ajaz, Stephen R.D. Johnston, Anne Thomas, Sue Chua, Gina Brown, Amanda Swain, Kerry Fenwick, Jian Ning, James Campbell, Ros Cutts, Claire Rooney, Catherine Geh, Neil R. Smith, Elaine Kilgour, Clare Peckitt, Noelia Tarazona, Maria Teresa Herrera-Abreu, Irina S. Babina, Elizabeth Smyth, Alex Pearson
Models of PI3 kinase-AKT signalling in FGFR driven cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261cf2bbe0960f40940fd18a23690b15
https://doi.org/10.1158/2159-8290.22531230.v1
https://doi.org/10.1158/2159-8290.22531230.v1
Autor:
Maurice Lobo, Ivan Marquez-Rodas, Jesus Zoco, Michael Smylie, Mazhar Ajaz, Alexander M. Menzies, Céleste Lebbé, Nicolas Meyer, Piotr Rutkowski, Ana Arance, Caroline Robert, Nikhil I. Khushalani, Thomas Eigentler, Paolo A. Ascierto, Jacopo Pigozzo, Inge Marie Svane, Laurent Mortier, Marcus O. Butler
Publikováno v:
Annales de Dermatologie et de Vénéréologie - FMC. 1:A133-A134