Sortilin regulates sorting and secretion of Sonic hedgehog

Autor: Campbell, C., Beug, S., Nickerson, P.E.B., Peng, J., Mazerolle, C., Bassett, E., Ringuette, R., Jama, F.A., Morales, C., Christ, A., Wallace, V.A.

Sonic Hedgehog (Shh) is a secreted morphogen that is an essential regulator of patterning and growth. The Shh full-length protein undergoes autocleavage in the ER to generate the biologically active amino-terminal ShhN fragment, which is destined for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=mdc______med::ae7f2cefa71481f16fdf56a35fa86904
http://edoc.mdc-berlin.de/16007/1/16007oa.pdf

Regulating the formation of Müller glia-derived progenitor cells in the retina.

Autor: Taylor OB; Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio, USA.; Neuroscience Graduate Program, The Ohio State University, Columbus, Ohio, USA., El-Hodiri HM; Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio, USA., Palazzo I; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Massachusetts, USA., Todd L; Department of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, New York, USA., Fischer AJ; Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio, USA.

Publikováno v: Glia [Glia] 2025 Jan; Vol. 73 (1), pp. 4-24. Date of Electronic Publication: 2024 Oct 24.

Identification and Characterization of ATOH7-Regulated Target Genes and Pathways in Human Neuroretinal Development.

Autor: Atac, David¹ (AUTHOR) grubichatac@medmolgen.uzh.ch, Maggi, Kevin¹ (AUTHOR) kmaggi@medmolgen.uzh.ch, Feil, Silke¹ (AUTHOR) feil@medmolgen.uzh.ch, Maggi, Jordi¹ (AUTHOR) maggi@medmolgen.uzh.ch, Cuevas, Elisa² (AUTHOR) j.sowden@ucl.ac.uk, Sowden, Jane C.² (AUTHOR), Koller, Samuel¹ (AUTHOR) koller@medmolgen.uzh.ch, Berger, Wolfgang^1,3,4 (AUTHOR) berger@medmolgen.uzh.ch

Publikováno v: Cells (2073-4409). Jul2024, Vol. 13 Issue 13, p1142. 33p.

Caractéristiques cliniques, biochimiques, cellulaires et moléculaires des phéochromocytomes incidentaux

Autor: Haissaguerre, M. ^a, Courel, M. ^b, Caron, P. ^c, Denost, S. ^a, Dubessy, C. ^b, Gosse, P. ^d, Apavouppoulle, V. ^e, Belleannée, G. ^f, Jullié, M.L. ^f, Montero-Hadjadje, M. ^b, Yon, L. ^b, Corcuff, J.B. ^g, Fagour, C. ^h, Mazerolle, C. ⁱ, Wagner, T. ^j, Nunes, M.L. ^a, Anouar, Y. ^b, Tabarin, A. ^a

Publikováno v: In Annales d'Endocrinologie September 2013 74(4):255-255

Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.

Autor: Bassett EA; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., Tokarew N; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada., Allemano EA; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., Mazerolle C; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., Morin K; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., Mears AJ; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., McNeill B; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., Ringuette R; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada., Campbell C; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada., Smiley S; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada., Pokrajac NT; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Canada., Dubuc AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Canada., Ramaswamy V; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Canada.; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada., Northcott PA; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Canada., Remke M; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Canada., Monnier PP; Genetics and Development Division, Krembil Research Institute, University Health Network, Toronto, Canada.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada., Potter D; Department of Ophthalmology, Lexicon Pharmaceuticals Inc., The Woodlands, United States., Paes K; Department of Ophthalmology, Lexicon Pharmaceuticals Inc., The Woodlands, United States., Kirkpatrick LL; Department of Ophthalmology, Lexicon Pharmaceuticals Inc., The Woodlands, United States., Coker KJ; Department of Ophthalmology, Lexicon Pharmaceuticals Inc., The Woodlands, United States., Rice DS; Department of Ophthalmology, Lexicon Pharmaceuticals Inc., The Woodlands, United States., Perez-Iratxeta C; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada., Taylor MD; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Canada., Wallace VA; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada.; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Canada.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.

Publikováno v: ELife [Elife] 2016 Nov 08; Vol. 5. Date of Electronic Publication: 2016 Nov 08.