Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Mazen Es-Sayed"'
Autor:
Jean-Pierre Vors, Emilie Rouchaud, Stéphanie Norsikian, Lionel Nicolas, Thomas Dröge, Mazen Es-Sayed, Jean-Marie Beau, Margaux Beretta
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2021, ⟨10.1039/d1ob00493j⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2021, ⟨10.1039/d1ob00493j⟩
International audience; The synthesis of glycopyranosyl nucleosides modified in the sugar moiety is less frequently explored, notably because of a lack of a reliable method to glycosylate pyrimidine bases. Herein we report a solution in the context o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f430667c20d12c46c5317d4021480cea
https://pubmed.ncbi.nlm.nih.gov/33885694
https://pubmed.ncbi.nlm.nih.gov/33885694
Publikováno v:
European Journal of Organic Chemistry. 2011:3837-3848
The 1,3-dipolar cycloaddition of diversely N-substituted 4-iodosydnones with 3-halopropiolates produces easily separable mixtures of dihalogenated pyrazolylcarboxylic esters at a preparative scale level, with the 3,5-dihalogenopyrazole regioisomers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e081daa3cfb78a2b9d4b454d99ed9c87
https://doi.org/10.1002/ejoc.201100119
https://doi.org/10.1002/ejoc.201100119
Publikováno v:
Synthesis. 2010:3439-3448
Fluoroolefins, which play an increasingly important role as peptide mimics in pharmaceuticals and as crop protection agents, are generated using a fluoro-Julia Kocienski olefination. Their preparation can easily be accomplished using a Mitsunobu reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17978510bdd23ccb2a5e6fdd156aacfb
https://doi.org/10.1055/s-0030-1258198
https://doi.org/10.1055/s-0030-1258198
Autor:
Stefan Bräse, Sylvia Vanderheiden, Thierry Muller, Martin Nieger, Rüdiger Reingruber, Mazen Es-Sayed
Publikováno v:
Tetrahedron Letters. 50:3439-3442
Acylated o-triazenylbenzylamines were cyclized to give 3-acyl-3,4-dihydrobenzo[d][1,2,3]triazines in good yields. Thus, a novel cyclization via a Jacobsen indazole-type reaction to aminoindazoles is observed in this context.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3d4a7bc7c39172555bea60f1e76c637
https://doi.org/10.1016/j.tetlet.2009.02.184
https://doi.org/10.1016/j.tetlet.2009.02.184
Autor:
Mazen Es-Sayed, Sylvia Vanderheiden, Martin Nieger, Alfred Wagner, Stefan Bräse, Rüdiger Reingruber, Thierry Muller
Publikováno v:
European Journal of Organic Chemistry. 2008:3314-3327
The stability of various substituted aryl-3,3-dialkyltriazenes, valuable synthetic intermediates, under several reaction conditions has been evaluated. To do so, anthranilonitrile and 2-amino-6-(trifluoromethyl)benzonitrile have been reacted in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae200060afa3ccdd4a4ca26779c5092b
https://doi.org/10.1002/ejoc.200800154
https://doi.org/10.1002/ejoc.200800154
Publikováno v:
European Journal of Organic Chemistry. 2008:3709-3713
Michael additions of carboxamides 2a–d under basic conditions onto methyl 2-chloro-2-cyclopropylideneacetate (1) with subsequent ring closure furnished the 4-spirocyclopropanated methyl oxazolinecarboxylates 3a–d (51–81 % yields), from which th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42172f2a707846741cc14d5efb91a4c7
https://doi.org/10.1002/ejoc.200800333
https://doi.org/10.1002/ejoc.200800333
Publikováno v:
European Journal of Organic Chemistry. 2005:3008-3016
The two new analogues 2 and 3 of the natural dipeptide antibiotic TAN 1057 A/B (1), both with cyclopropyl containing β-amino acid side chains, were prepared. The synthesis of the corresponding β-amino acids in appropriately protected form (4-Z3 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::298a30f075e9b832527eea213366d4c4
https://doi.org/10.1002/ejoc.200500177
https://doi.org/10.1002/ejoc.200500177
Publikováno v:
European Journal of Organic Chemistry. 2005:2250-2258
Methyl 1-(tert-butoxycarbonylamino)cyclopropanecarboxylate (9) was converted into the spirocyclopropanated five-membered ring analogue 7a of Iprodione (1) in five steps with an overall yield of 28 %. The spirocyclopropanated five-membered ring analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a59a35d5eeb4a720d6103458f5b962fc
https://doi.org/10.1002/ejoc.200400600
https://doi.org/10.1002/ejoc.200400600
Autor:
Michael Limbach, Jörg Magull, Mazen Es-Sayed, Armin de Meijere, André Janssen, Suryakanta Dalai
Publikováno v:
European Journal of Organic Chemistry. 2005:610-617
Indole readily added across the double bond of the highly reactive Michael acceptor methyl 2-chloro-2-cyclopropylideneacetate (4) to yield 2-chloro-2-(3′-indolylcyclopropyl)acetate 5 (85%) which was converted in two steps into the racemic tryptopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f503aed83d872d05e73e1ab9677f19ee
https://doi.org/10.1002/ejoc.200400617
https://doi.org/10.1002/ejoc.200400617
Autor:
Thomas Lampe, Erwin Bischoff, Thomas Schenke, Gunter Schmidt, Ulrich Niewöhner, Helmut Haning, Mazen Es-Sayed
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:865-868
2-aryl-substituted imidazo[5,1-f][1,2,4]triazin-4(3H)-ones represent a new class of potent cGMP-PDE 5 inhibitors that prove to be superior to other purine-isosteric inhibitors. Subnanomolar inhibitors of PDE 5 with activity in in vivo models for erec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d86086a94bf41b7d8b95a8d001f9e6a
https://doi.org/10.1016/s0960-894x(02)00030-6
https://doi.org/10.1016/s0960-894x(02)00030-6