Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mazal Elnekave"'
Autor:
Karina Furmanov, Mazal Elnekave, Abdallah Sa'eed, Hadas Segev, Luba Eli-Berchoer, Darrell N Kotton, Gilad Bachrach, Avi-Hai Hovav
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66488 (2013)
Memory CD8(+) T lymphocytes play a central role in protective immunity. In attempt to increase the frequencies of memory CD8(+) T cells, repeated immunizations with viral vectors are regularly explored. Lentivectors have emerged as a powerful vaccine
Externí odkaz:
https://doaj.org/article/41fa69051e6c4e0e8e9fdfe8559943ea
Autor:
Elad Horwitz, Moshe Sade-Feldman, Julia Kanterman, Michal Baniyash, Mazal Elnekave, Eliran Ish-Shalom
Publikováno v:
Immunity. 38:541-554
Summary Elevated concentrations of tumor necrosis factor-α (TNF-α) are detected in pathologies characterized by chronic inflammation. Whether TNF-α plays a role in manipulating the host's immune system toward generating an immunosuppressive milieu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0922b993c02a344c2e5ab385bf82c3
https://doi.org/10.1016/j.immuni.2013.02.007
https://doi.org/10.1016/j.immuni.2013.02.007
Dendritic Cells in Distinct Oral Mucosal Tissues Engage Different Mechanisms To Prime CD8(+) T Cells
Autor:
Björn E. Clausen, Avi-Hai Hovav, Moran Arizon, Asaf Wilensky, Itay Nudel, Mazal Elnekave, Karina Furmanov
Publikováno v:
Journal of Immunology, 186(2), 891-900. American Association of Immunologists
Europe PubMed Central
Europe PubMed Central
Although oral dendritic cells (DCs) were shown to induce cell-mediated immunity, the identity and function of the various oral DC subsets involved in this process is unclear. In this study, we examined the mechanisms used by DCs of the buccal mucosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8e843ea89a36c5be2bb1a223735560
https://pure.eur.nl/en/publications/2ccee09a-c33b-431a-8eff-e1c28d2d2943
https://pure.eur.nl/en/publications/2ccee09a-c33b-431a-8eff-e1c28d2d2943
Publikováno v:
Journal of Immunology, 185(6), 3463-3471. American Association of Immunologists
Europe PubMed Central
Europe PubMed Central
Dendritic cells (DCs) play a critical role in CD8(+) T cell priming following DNA vaccination. In contrast to other DNA injection routes or immunization with viral vectors, Ag presentation is delayed following needle injection of plasmid DNA into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e3252249e496bfac160b0fe0633721
https://doi.org/10.4049/jimmunol.1001825
https://doi.org/10.4049/jimmunol.1001825
Publikováno v:
The Journal of Immunology. 183:1013-1021
Despite the low and short expression of secondary Ag, prime-boost immunizations using homologous or heterologous vectors are capable of amplifying memory CD8+ T cells. This is mainly attributed to the rapid presentation of Ag by APCs and the high pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9af45c5d8483865dc6ed7a7305a5b78
https://doi.org/10.4049/jimmunol.0900283
https://doi.org/10.4049/jimmunol.0900283
Autor:
Luba Eli-Berchoer, Karina Furmanov, Björn E. Clausen, Avi-Hai Hovav, Tal Capucha, Mazal Elnekave, Katya Zelentsova, Yaffa Shaul
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(4)
In vivo studies questioned the ability of Langerhans cells (LCs) to mediate CD8+ T cell priming. To address this issue, we used intradermal immunization with plasmid DNA, a system in which activation of CD8+ T cells depends on delayed kinetics of Ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bf4c302108ed3c7b5c79ede486063c
https://pubmed.ncbi.nlm.nih.gov/24420922
https://pubmed.ncbi.nlm.nih.gov/24420922
Publikováno v:
Expert review of vaccines. 10(8)
Plasmid DNA is a promising vaccine modality that is regularly examined in prime-boost immunization regimens. Recent advances in skin immunity increased our understanding of the sophisticated cutaneous immune network, which revived scientific interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96809027a872fc5dd551258d4bc2fd47
https://pubmed.ncbi.nlm.nih.gov/21854310
https://pubmed.ncbi.nlm.nih.gov/21854310
Autor:
Avi-Hai Hovav, Darrell N. Kotton, Björn E. Clausen, Mazal Elnekave, Karina Furmanov, D. Lehmann
Publikováno v:
Europe PubMed Central
Journal of Immunology, 184(9), 4889-4897. American Association of Immunologists
Journal of Immunology, 184(9), 4889-4897. American Association of Immunologists
Although skin dendritic cells (DCs) have been shown to directly present Ag to CD8(+) T cells after intradermal immunization with lentivectors, the contribution of the different skin DC subsets to this process remains unclear. Using langerin-diphtheri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8567e027a36a9120fde645e83fcf1d61
https://pubmed.ncbi.nlm.nih.gov/20357252
https://pubmed.ncbi.nlm.nih.gov/20357252
Autor:
Alexander C Cheng, Michael Santosuosso, Avi-Hai Hovav, Mazal Elnekave, Elda Righi, Michael W. Panas, Tao Chen, Norman L. Letvin, Satoshi Kashiwagi, Mark C. Poznansky, Maytal Bivas-Benita, Shi Hua Xiang, Andre Plair, Karina Furmanov
Publikováno v:
Journal of virology. 83(21)
In order to increase the immune breadth of human immunodeficiency virus (HIV) vaccines, strategies such as immunization with several HIV antigens or centralized immunogens have been examined. HIV-1 gp120 protein is a major immunogen of HIV and has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04ece1556a711a2e485469ead9a2588
https://pubmed.ncbi.nlm.nih.gov/19692474
https://pubmed.ncbi.nlm.nih.gov/19692474
Autor:
Björn E. Clausen, Gabriel Mizraji, Mazal Elnekave, Asaf Wilensky, Luba Eli-Berchoer, Avi-Hai Hovav, Karina Furmanov, Lior Shapira, Moran Arizon, Itay Nudel, Hadas Segev
Publikováno v:
Europe PubMed Central
Proceedings of the National Academy of Sciences of the U.S.A., 109(18), 7043-7048. National Academy of Sciences
Proceedings of the National Academy of Sciences of the U.S.A., 109(18), 7043-7048. National Academy of Sciences
Excessive bone resorption is frequently associated with chronic infections and inflammatory diseases. Whereas T cells were demonstrated to facilitate osteoclastogenesis in such diseases, the role of dendritic cells, the most potent activators of naiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bfe7233a625b3c162a3427847f59a1
http://europepmc.org/abstract/med/22509018
http://europepmc.org/abstract/med/22509018
