Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Mayuresh M Abhyankar"'
Autor:
Koji Watanabe, Carol A Gilchrist, Md Jashim Uddin, Stacey L Burgess, Mayuresh M Abhyankar, Shannon N Moonah, Zannatun Noor, Jeffrey R Donowitz, Brittany N Schneider, Tuhinur Arju, Emtiaz Ahmed, Mamun Kabir, Masud Alam, Rashidul Haque, Patcharin Pramoonjago, Borna Mehrad, William A Petri
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006513 (2017)
The disease severity of Entamoeba histolytica infection ranges from asymptomatic to life-threatening. Recent human and animal data implicate the gut microbiome as a modifier of E. histolytica virulence. Here we have explored the association of the mi
Externí odkaz:
https://doaj.org/article/63e5e114af534237a48f082c7b70c26a
Autor:
Mayuresh M. Abhyankar, Feifan Xu, Deborah Chavez, Anna Goodroe, Elda Mendoza, Christopher Chen, Dhiraj K. Singh, Fernando Varnador, Sandra J. Sivananthan, Robert Kinsey, William R. Lykins, Brynn M. Murphy, Andrew R. Martin, Mark A. Tomai, Soutik Ghosal, Corey Casper, Karl Pedersen, William A. Petri, Christopher B. Fox
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Entamoeba histolytica, the causative agent of amebiasis, is one of the top three parasitic causes of mortality worldwide. However, no vaccine exists against amebiasis. Using a lead candidate vaccine containing the LecA fragment of Gal-lectin and GLA-
Externí odkaz:
https://doaj.org/article/551da17c7f22488f90dafec622622cb9
Autor:
Rupin Kumar, Sherry L. Kausch, Angela K. S. Gummadi, Karen D. Fairchild, Mayuresh M. Abhyankar, William A. Petri, Brynne A. Sullivan
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundEarly diagnosis of late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) in very low birth weight (VLBW,
Externí odkaz:
https://doaj.org/article/095b0ff606fe4d52b1735153d3f88cb8
Autor:
Mayuresh M. Abhyankar, Barbara J. Mann, Jeffrey M. Sturek, Savannah Brovero, G. Brett Moreau, Anjali Sengar, Crystal M. Richardson, Sayeh Agah, Anna Pomés, Peter M. Kasson, Mark A. Tomai, Christopher B. Fox, William A. Petri
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-6 (2021)
Abstract We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and completely protected mice from a lethal challenge. Two immunizations pr
Externí odkaz:
https://doaj.org/article/da4da1c7c88a4956b31769225afbc2c2
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
Autor:
Alyse L. Frisbee, Mahmoud M. Saleh, Mary K. Young, Jhansi L. Leslie, Morgan E. Simpson, Mayuresh M. Abhyankar, Carrie A. Cowardin, Jennie Z. Ma, Patcharin Pramoonjago, Stephen D. Turner, Alice P. Liou, Erica L. Buonomo, William A. Petri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Here, Frisbee et al. show that hypervirulent Clostridium difficile induces IL-33 expression in the gut and IL-33 reduces mortality and morbidity via group 2 innate lymphoid cells. Furthermore, serum levels of the soluble IL-33 decoy receptor, sST2, a
Externí odkaz:
https://doaj.org/article/8ea0571b5e634edeb6f07d5f54e6abfd
Autor:
Mayuresh M. Abhyankar, Jennie Z. Ma, Kenneth W. Scully, Andrew J. Nafziger, Alyse L. Frisbee, Mahmoud M. Saleh, Gregory R. Madden, Ann R. Hays, Mendy Poulter, William A. Petri
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT There is a pressing need for biomarker-based models to predict mortality from and recurrence of Clostridioides difficile infection (CDI). Risk stratification would enable targeted interventions such as fecal microbiota transplant, antitoxin
Externí odkaz:
https://doaj.org/article/39ddbbd2dd9b412bb8754c0a4f511fdc
Autor:
Genevieve L. Wojcik, Chelsea Marie, Mayuresh M. Abhyankar, Nobuya Yoshida, Koji Watanabe, Alexander J. Mentzer, Tommy Carstensen, Josyf Mychaleckyj, Beth D. Kirkpatrick, Stephen S. Rich, Patrick Concannon, Rashidul Haque, George C. Tsokos, William A. Petri, Priya Duggal
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Entamoeba histolytica is the etiologic agent of amebic dysentery, though clinical manifestation of infection is highly variable ranging from subclinical colonization to invasive disease. We hypothesize that host genetics contribute to the va
Externí odkaz:
https://doaj.org/article/30e31e72edca45648e51806ad021ee46
Autor:
Gregory R. Madden, Isaura Rigo, Rachel Boone, Mayuresh M. Abhyankar, Mary K. Young, William Basener, William A. Petri
Publikováno v:
Infection and Immunity. 91
Traditional clinical models for predicting recurrent Clostridioides difficile infection do not perform well, likely owing to the complex host-pathogen interactions involved. Accurate risk stratification using novel biomarkers could help prevent recur
Autor:
Julio Revilla, William A. Petri, Noah Oakland, Jashim Uddin, Jhansi L. Leslie, Brandon L. Thompson, Pankaj Kumar, Alyse Frisbee, Stacey L. Burgess, Alexandra N. Donlan, Mayuresh M. Abhyankar
Publikováno v:
Mucosal Immunology
Entamoeba histolytica is a pathogenic protozoan parasite that causes intestinal colitis, diarrhea, and in some cases, liver abscess. Through transcriptomics analysis, we observed that E. histolytica infection was associated with increased expression
Autor:
Zannatun Noor, Koji Watanabe, Mayuresh M. Abhyankar, Stacey L. Burgess, Erica L. Buonomo, Carrie A. Cowardin, William A. Petri
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT The parasite Entamoeba histolytica is a cause of diarrhea in infants in low-income countries. Previously, it was shown that tumor necrosis factor alpha (TNF-α) production was associated with increased risk of E. histolytica diarrhea in chil
Externí odkaz:
https://doaj.org/article/e519dcf2d42649cf8a4465901b96d7f2