Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mayurakhi Dutta"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 3, Iss 1, Pp 11-17 (2017)
Rational approach to drug design is the process to find new potent molecules on the basis of a known target and available ligands for the target. Compared to the traditional system of drug design and discovery, that involves blind testing of differen
Externí odkaz:
https://doaj.org/article/95638cf1e7ee478f8c2ef0624127d6e1
Publikováno v:
Experimental parasitology. 163
Existing antifolate antimalarial drugs have shown resistance due to the mutations at some amino acid positions of Plasmodium falciparum DHFR-TS. In the present study, to overcome this resistance, a new series of hybrid 4-aminoquinoline-triazine deriv