Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mayura Dhamdhere"'
Autor:
Jason M. Biegel, Mayura Dhamdhere, Shuang Gao, Chethana P. Gowda, Yuka Imamura Kawasawa, Vladimir S. Spiegelman
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Gain at chromosome 17q21 in neuroblastoma is associated with a poor prognosis, independent of MYCN amplification status. Several potential proto-oncogenes have been identified in this region, one of them—insulin-like growth-factor-2 mRNA binding pr
Externí odkaz:
https://doaj.org/article/74caff8d27094cf3bbda96c572fc8679
Autor:
Mayinuer Maitituoheti, Emily Z. Keung, Ming Tang, Liang Yan, Hunain Alam, Guangchun Han, Anand K. Singh, Ayush T. Raman, Christopher Terranova, Sharmistha Sarkar, Elias Orouji, Samir B. Amin, Sneha Sharma, Maura Williams, Neha S. Samant, Mayura Dhamdhere, Norman Zheng, Tara Shah, Amiksha Shah, Jacob B. Axelrad, Nazanin E. Anvar, Yu-Hsi Lin, Shan Jiang, Edward Q. Chang, Davis R. Ingram, Wei-Lien Wang, Alexander Lazar, Min Gyu Lee, Florian Muller, Linghua Wang, Haoqiang Ying, Kunal Rai
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108293- (2020)
Summary: Histone methyltransferase KMT2D harbors frequent loss-of-function somatic point mutations in several tumor types, including melanoma. Here, we identify KMT2D as a potent tumor suppressor in melanoma through an in vivo epigenome-focused poole
Externí odkaz:
https://doaj.org/article/c36af48cd2dc464096d008d1f2795abf
Autor:
Petko Fiziev, Kadir C. Akdemir, John P. Miller, Emily Z. Keung, Neha S. Samant, Sneha Sharma, Christopher A. Natale, Christopher J. Terranova, Mayinuer Maitituoheti, Samirkumar B. Amin, Emmanuel Martinez-Ledesma, Mayura Dhamdhere, Jacob B. Axelrad, Amiksha Shah, Christine S. Cheng, Harshad Mahadeshwar, Sahil Seth, Michelle C. Barton, Alexei Protopopov, Kenneth Y. Tsai, Michael A. Davies, Benjamin A. Garcia, Ido Amit, Lynda Chin, Jason Ernst, Kunal Rai
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 875-889 (2017)
The extent and nature of epigenomic changes associated with melanoma progression is poorly understood. Through systematic epigenomic profiling of 35 epigenetic modifications and transcriptomic analysis, we define chromatin state changes associated wi
Externí odkaz:
https://doaj.org/article/fba1822f041e4353b3a276ef7a4506d3
Autor:
Mayura Dhamdhere, Jason M. Biegel, Shuang Gao, Vladimir S. Spiegelman, Yuka Imamura Kawasawa, Chethana P. Gowda
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Gain at chromosome 17q21 in neuroblastoma is associated with a poor prognosis, independent of MYCN amplification status. Several potential proto-oncogenes have been identified in this region, one of them—insulin-like growth-factor-2 mRNA binding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9147635f3e8449e169e46428e6bb769
https://doi.org/10.3389/fonc.2021.608816
https://doi.org/10.3389/fonc.2021.608816
Autor:
Kadir C. Akdemir, Sahil Seth, Kunal Rai, Jason Ernst, Jacob B. Axelrad, Emmanuel Martinez-Ledesma, Harshad S. Mahadeshwar, Neha S. Samant, Kenneth Y. Tsai, Ido Amit, Samirkumar B. Amin, Christopher A. Natale, Emily Z. Keung, John P. Miller, Mayinuer Maitituoheti, Christine S. Cheng, Lynda Chin, Alexei Protopopov, Amiksha Shah, Michelle Craig Barton, Mayura Dhamdhere, Sneha Sharma, Petko Fiziev, Christopher Terranova, Benjamin A. Garcia, Michael A. Davies
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 875-889 (2017)
Cell reports, vol 19, iss 4
Cell reports, vol 19, iss 4
The extent and nature of epigenomic changes associated with melanoma progression is poorly understood. Through systematic epigenomic profiling of 35 epigenetic modifications and transcriptomic analysis, we define chromatin state changes associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513eccc6e13994e50f42a0fd1fd525ff
http://www.sciencedirect.com/science/article/pii/S2211124717304552
http://www.sciencedirect.com/science/article/pii/S2211124717304552
Autor:
Ayush T. Raman, Ming Tang, Liang Yan, Emily Z. Keung, Guangchun Han, Maura Williams, Linghua Wang, Florian L. Muller, Wei Lien Wang, Amiksha Shah, Norman Zheng, Hunain Alam, Min Gyu Lee, Yu Hsi Lin, Christopher Terranova, Davis R. Ingram, Haoqiang Ying, Edward Q. Chang, Tara Shah, Shan Jiang, Samir B. Amin, Alexander J. Lazar, Elias Orouji, Mayinuer Maitituoheti, Jacob B. Axelrad, Kunal Rai, Nazanin Esmaeili Anvar, Mayura Dhamdhere, Sharmistha Sarkar, Sneha Sharma, Anand K Singh, Neha S. Samant
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108293-(2020)
Cell reports
Cell reports
SUMMARY Histone methyltransferase KMT2D harbors frequent loss-of-function somatic point mutations in several tumor types, including melanoma. Here, we identify KMT2D as a potent tumor suppressor in melanoma through an in vivo epigenome-focused pooled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02072ce246e19287ad40b288974bded
Autor:
Kunal Rai, Neha S. Samant, Mayinuer Maitituoheti, Kadir C. Akdemir, Christopher Terranova, Petko Fiziev, Amikhsha Shah, Ming Tang, Elias Orouji, Mayura Dhamdhere, Sneha Sharma, Lynda Chin, Jason Ernst
Publikováno v:
Cancer Research. 78:4314-4314
The extent and nature of epigenomic changes associated with melanoma progression is poorly understood. To determine chromatin state patterns of human metastatic melanomas, we defined epigenome of melanoma by profiling 6 histone modification marks (H3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1392df485d24353caa8647004b8140e
https://doi.org/10.1158/1538-7445.am2018-4314
https://doi.org/10.1158/1538-7445.am2018-4314
Publikováno v:
Cancer Research. 78:4315-4315
Cancer cells utilize genetic and epigenetic aberrations for their excessive growth. Although we have sufficient understanding of the genomic alterations in colorectal cancer, we have incomplete knowledge of epigenomic aberrations and their impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fc2f9494d98b1c515a7ee41756822f3
https://doi.org/10.1158/1538-7445.am2018-4315
https://doi.org/10.1158/1538-7445.am2018-4315