Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mayur Suryakant Dudhedia"'
Autor:
Klaus Pekari, James Segretario, Florian Sommer, Thomas Fürst, Rüdiger Gössl, Mayur Suryakant Dudhedia, Patricia Watson
Publikováno v:
Therapeutic Innovation & Regulatory Science. 50:204-212
The differentiation of tablets by their physical appearance is a contributing factor to the safe use of medications. In this study, a “score card” was developed to assess how well one tablet is differentiated from another tablet on the basis of t
Publikováno v:
AAPS PharmSciTech. 17:133-147
The objective of the study was to develop an amorphous solid dispersion (ASD) for an insoluble compound X by hot melt extrusion (HME) process. The focus was to identify material-sparing approaches to develop bioavailable and stable ASD including scal
Autor:
Mayur Suryakant Dudhedia, Madhuri Jerfy, Fenghe Qiu, Zeena Williams, Anjali Agrawal, Ashish Soman
ICH and WHO stability guidelines require minimum 6–12 months of stability data at recommended long-term and accelerated conditions to support the expiry dating for registration. This approach is problematic in early clinical development because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fecfd36d92566630f87c68676a883afe
https://doi.org/10.1016/b978-0-12-802786-8.00013-9
https://doi.org/10.1016/b978-0-12-802786-8.00013-9
Autor:
Anjali Agrawal, Mayur Suryakant Dudhedia, Edward Povilaitis, Li Zhong, Weibin Deng, Kevin Shepard, Ewa Zimny
The objective of the study was to identify the extragranular component requirements (level and type of excipients) to develop an immediate release tablet of solid dispersions prepared by hot melt extrusion (HME) process using commonly used HME polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26dbcc358d9990c76abc8548a4eb0e4
https://europepmc.org/articles/PMC4766115/
https://europepmc.org/articles/PMC4766115/
Publikováno v:
Journal of Applied Polymer Science. 133
The focus of this work is to generate rheological parameters using AR 2000EX rheometer for PVP VA64 and Compound A – PVP VA64 blend at different temperatures, which can then be subsequently used to identify hot melt extrusion process conditions. Ad
Publikováno v:
International journal of pharmaceutics. 457(1)
The present study investigated effect of manufacturing methods such as hot melt extrusion (HME) and spray drying (SD) on physicochemical properties, manufacturability, physical stability and product performance of solid dispersion. Solid dispersions
Autor:
Li Zhong, Schwabe Robert J, Amy Birch, Johanna Ubben, Chen Feng-Jing, Mayur Suryakant Dudhedia, Frank M. Etzler
Publikováno v:
Journal of pharmaceutical sciences. 99(1)
The present study investigated the effect of lipophilic components on the compatibility of propylene glycol (PG)-containing lipid-based drug delivery system (LBDDS) formulations with hard gelatin capsules. The presence of a lipophilic active pharmace
Autor:
Mayur Suryakant Dudhedia, Steven L. Krill, John A. Smoliga, Zeren Wang, Paul-James Jones, Toby Tamblyn, Richard T. Darrington, Shirlynn Chen
Publikováno v:
Journal of pharmaceutical sciences. 98(5)
This report describes the solubility properties of a poorly soluble drug-excipient complex in a lipid based formulation. Tipranavir (TPV) was used as the model drug and 1,3-dioctanoylglycerol (DOG) as the excipient. The TPV-DOG complex was prepared b