Výsledky vyhledávání - "Mayur Lodaya"

Use of surfactants as plasticizers in preparing solid dispersions of poorly soluble API: Selection of polymer–surfactant combinations using solubility parameters and testing the processability

Autor: Mayur Lodaya, Alazar N. Ghebremeskel, Chandra Vemavarapu

Publikováno v: International Journal of Pharmaceutics. 328:119-129

Formation of solid dispersions as a means to enhance the dissolution rate of poorly soluble Active pharmaceutical ingredients (APIs) typically employs hydrophilic polymer systems and surfactants. While the utility of the surfactant systems in solubil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503122c625c62306d442884072776134
https://doi.org/10.1016/j.ijpharm.2006.08.010

Zobrazit plný text záznamu

Ring-opening polymerization of epoxy end-terminated poly(ethylene oxide) as a route to highly crosslinked materials with exceptional swelling behavior (II)

Autor: Mathew Mollan, Mayur Lodaya, Richard M. Laine, S. G. Kim, Jason Rush, Hei-Jen Sun

Publikováno v: Polymer International. 56:1006-1015

Highly swellable poly(ethylene oxide) (PEO) gels were prepared by anionic ring-opening polymerization of diepoxy end-capped PEO (3400gmol −1 ) and PEO (8000gmol −1 ) using dianionic glycerol and glycolic acid initiators at scales of up to 50g die

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07f3354c4481e0c6f3ada693199f834d
https://doi.org/10.1002/pi.2234

Zobrazit plný text záznamu

Design and process aspects of laboratory scale SCF particle formation systems

Autor: Mayur Lodaya, Thomas E. Needham, Matthew J. Mollan, Chandra Vemavarapu

Publikováno v: International Journal of Pharmaceutics. 292:1-16

Consistent production of solid drug materials of desired particle and crystallographic morphologies under cGMP conditions is a frequent challenge to pharmaceutical researchers. Supercritical fluid (SCF) technology gained significant attention in phar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a0dde6c0fd004f3098eb41b5a57edf
https://doi.org/10.1016/j.ijpharm.2004.07.021

Zobrazit plný text záznamu

Use of surfactants as plasticizers in preparing solid dispersions of poorly soluble API: stability testing of selected solid dispersions

Autor: Alazar N. Ghebremeskel, Mayur Lodaya, Chandra Vemavarapu

Publikováno v: Pharmaceutical research. 23(8)

The purpose of the study is to evaluate the effect of surfactant-plasticizers on the physical stability of amorphous drug in polymer matrices formed by hot melt extrusion.Solid dispersions of a poorly soluble drug were prepared using PVP-K30, Plasdon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128ef8013e96568ee31dd88ec65ee6be
https://pubmed.ncbi.nlm.nih.gov/16871443

Zobrazit plný text záznamu