Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Mayumi Iwatake"'
Autor:
Saho Morita, Mayumi Iwatake, Sakura Suga, Kazuomi Takahashi, Kazuhide Sato, Chika Miyagi-Shiohira, Hirofumi Noguchi, Yoshinobu Baba, Hiroshi Yukawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pulmonary fibrosis is a progressive disease caused by interstitial inflammation. Treatments are extremely scarce; therapeutic drugs and transplantation therapies are not widely available due to cost and a lack of donors, respectively. Recent
Externí odkaz:
https://doaj.org/article/edcf9faab1cb4f9b9b1576910eac4523
Autor:
Mayumi Iwatake, Tokiko Nagamura-Inoue, Ryoichiro Doi, Yukinori Tanoue, Mitsutoshi Ishii, Hiroshi Yukawa, Keitaro Matsumoto, Koichi Tomoshige, Takeshi Nagayasu, Tomoshi Tsuchiya
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundResearchers are focusing on cellular therapy for chronic obstructive pulmonary disease (COPD) using mesenchymal stem cells (MSCs), with human bone marrow-derived MSCs (hBM-MSCs) leading the way. However, BM-MSCs may not be as optimal as the
Externí odkaz:
https://doaj.org/article/7ad988deacae43bc99f4166829d65b13
Autor:
Makoto Hisanaga, Tomoshi Tsuchiya, Hironosuke Watanabe, Koichiro Shimoyama, Mayumi Iwatake, Yukinori Tanoue, Keizaburo Maruyama, Hiroshi Yukawa, Kazuhide Sato, Yoshimi Kato, Keitaro Matsumoto, Takuro Miyazaki, Ryoichiro Doi, Koichi Tomoshige, Takeshi Nagayasu
Publikováno v:
Organogenesis, Vol 19, Iss 1 (2023)
ABSTRACTDecellularized scaffolds are promising biomaterials for tissue and organ reconstruction; however, strategies to effectively suppress the host immune responses toward these implants, particularly those without chemical crosslinking, remain war
Externí odkaz:
https://doaj.org/article/b27db5d07d424242bfbcc4ecb7c1fbb9
Autor:
Yukinori Tanoue, Tomoshi Tsuchiya, Takuro Miyazaki, Mayumi Iwatake, Hironosuke Watanabe, Hiroshi Yukawa, Kazuhide Sato, Go Hatachi, Koichiro Shimoyama, Keitaro Matsumoto, Ryoichiro Doi, Koichi Tomoshige, Takeshi Nagayasu
Publikováno v:
Cell Transplantation, Vol 32 (2023)
Cell therapy using mesenchymal stromal cells (MSCs) is being studied for its immunosuppressive effects. In organ transplantation, the amount of MSCs that accumulate in transplanted organs and other organs may differ depending on administration timing
Externí odkaz:
https://doaj.org/article/07f5e29a03c84c5d918c44822628bd65
Autor:
Satoshi Mizoguchi, Tomoshi Tsuchiya, Ryoichiro Doi, Tomohiro Obata, Mayumi Iwatake, Shintaro Hashimoto, Hirotaka Matsumoto, Hiroshi Yukawa, Hiroko Hayashi, Tao-Sheng Li, Kazuko Yamamoto, Keitaro Matsumoto, Takuro Miyazaki, Koichi Tomoshige, Takeshi Nagayasu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Two-dimensional cell cultures have contributed substantially to lung cancer research, but 3D cultures are gaining attention as a new, more efficient, and effective research model. A model reproducing the 3D characteristics and tumor mic
Externí odkaz:
https://doaj.org/article/ee7d56c1f8b447fb85441f9dfff0f0f4
Autor:
Kayo Hasegawa, Jorge Luis Montenegro Raudales, Takashi I, Takako Yoshida, Ryo Honma, Mayumi Iwatake, Simon D. Tran, Makoto Seki, Izumi Asahina, Yoshinori Sumita
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Sjögren syndrome (SS) is an autoimmune disease characterized by salivary gland (SG) destruction leading to loss of secretory function. A hallmark of the disease is the presence of focal lymphocyte infiltration in SGs, which is predomin
Externí odkaz:
https://doaj.org/article/a2b68f48a0b5448bbfedb68509a160aa
Autor:
Ryo Honma, Takashi I, Makoto Seki, Mayumi Iwatake, Takunori Ogaeri, Kayo Hasegawa, Seigo Ohba, Simon D. Tran, Izumi Asahina, Yoshinori Sumita
Publikováno v:
Cells, Vol 12, Iss 10, p 1417 (2023)
A newly developed therapy using effective-mononuclear cells (E-MNCs) is reportedly effective against radiation-damaged salivary glands (SGs) due to anti-inflammatory and revascularization effects. However, the cellular working mechanism of E-MNC ther
Externí odkaz:
https://doaj.org/article/b788dc27d4484795b91cd6b0799d41ae
Autor:
Takashi I, Yoshinori Sumita, Takako Yoshida, Ryo Honma, Mayumi Iwatake, Jorge Luis Montenegro Raudales, Tomoko Shizuno, Shinichiro Kuroshima, Haruchika Masuda, Makoto Seki, Simon D. Tran, Takayuki Asahara, Izumi Asahina
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-15 (2019)
Abstract Background There are currently no effective treatments available for patients with irreversible loss of salivary gland (SG) function caused by radiation therapy for head and neck cancer. In this study, we have developed an effective culture
Externí odkaz:
https://doaj.org/article/448f92d1164846ddab9027d6a8c313c5
Autor:
Masahito Hara, Yoshinori Sumita, Yukinobu Kodama, Mayumi Iwatake, Hideyuki Yamamoto, Rena Shido, Shun Narahara, Takunori Ogaeri, Hitoshi Sasaki, Izumi Asahina
Publikováno v:
Materials, Vol 14, Iss 22, p 7097 (2021)
We have developed nanoballs, a biocompatible self-assembly nano-vector based on electrostatic interactions that arrange anionic macromolecules to polymeric nanomaterials to create nucleic acid carriers. Nanoballs exhibit low cytotoxicity and high tra
Externí odkaz:
https://doaj.org/article/f565e59bc16c48db8245e49dc5e5ee38
Autor:
Mitsutoshi Ishii, Tomoshi Tsuchiya, Ryoichiro Doi, Yoichi Morofuji, Takashi Fujimoto, Hideki Muto, Takashi Suematsu, Ryoichi Mori, Keitaro Matsumoto, Takuro Miyazaki, Koichi Tomoshige, Hironosuke Watanabe, Mayumi Iwatake, Takeshi Nagayasu
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1264 (2021)
With the emergence of coronavirus disease-2019, researchers have gained interest in the therapeutic efficacy of mesenchymal stem/stromal cells (MSCs) in acute respiratory distress syndrome; however, the mechanisms of the therapeutic effects of MSCs a
Externí odkaz:
https://doaj.org/article/9f85294ae8ab486a9e5ea0ed4f1f4a72