Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mayumi Hirayama"'
Publikováno v:
Frontiers in Hematology, Vol 2 (2023)
An R-loop is a nucleic acid structure consisting of a DNA : RNA hybrid and single-stranded DNA. It is formed physiologically in normal cells and is involved in transcription, replication, and gene rearrangement; in particular, it has multiple roles i
Externí odkaz:
https://doaj.org/article/361d068cf6bf4ec8ae5e16e746514bc4
Autor:
Kenta Kawahara, Masashi Nagata, Ryoji Yoshida, Akiyuki Hirosue, Takuya Tanaka, Yuichiro Matsuoka, Hidetaka Arita, Hikaru Nakashima, Junki Sakata, Keisuke Yamana, Sho Kawaguchi, Shunsuke Gohara, Yuka Nagao, Masatoshi Hirayama, Nozomu Takahashi, Mayumi Hirayama, Hideki Nakayama
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101114- (2021)
We aimed to determine the functional role of the miRNA, which affects drug sensitivity to 5-FU in oral squamous cell carcinoma (OSCC), using two types of 5-FU-resistant and parental OSCC cell lines. MiRNA microarray data showed that miR-30a was signi
Externí odkaz:
https://doaj.org/article/c4cd0de1a81d41e3abda7092abd3378d
Autor:
Mayumi Hirayama, Fan-Yan Wei, Takeshi Chujo, Shinya Oki, Maya Yakita, Daiki Kobayashi, Norie Araki, Nozomu Takahashi, Ryoji Yoshida, Hideki Nakayama, Kazuhito Tomizawa
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: N6-Methyladenosine (m6A) modification is the major chemical modification in mRNA that controls fundamental biological processes, including cell proliferation. Herein, we demonstrate that fat mass and obesity-associated (FTO) demethylates m6A
Externí odkaz:
https://doaj.org/article/b31306cd90024b878954550d4a52dce1
Autor:
Satoru Shinriki, Mayumi Hirayama, Akiko Nagamachi, Akihiko Yokoyama, Takeshi Kawamura, Akinori Kanai, Hidehiko Kawai, Junichi Iwakiri, Rin Liu, Manabu Maeshiro, Saruul Tungalag, Masayoshi Tasaki, Mitsuharu Ueda, Kazuhito Tomizawa, Naoyuki Kataoka, Takashi Ideue, Yutaka Suzuki, Kiyoshi Asai, Tokio Tani, Toshiya Inaba, Hirotaka Matsui
Publikováno v:
Leukemia. 36:2605-2620
Myeloid malignancies with DDX41 mutations are often associated with bone marrow failure and cytopenia before overt disease manifestation. However, the mechanisms underlying these specific conditions remain elusive. Here, we demonstrate that loss of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788aa1190ebda86839e97eca377f1e1b
https://doi.org/10.1038/s41375-022-01708-9
https://doi.org/10.1038/s41375-022-01708-9
Autor:
Maya Yakita, Takeshi Chujo, Fan-Yan Wei, Mayumi Hirayama, Koji Kato, Nozomu Takahashi, Kenta Naganuma, Masashi Nagata, Kenta Kawahara, Hideki Nakayama, Kazuhito Tomizawa
Publikováno v:
RNA. 28:1013-1027
N6-isopentenyladenosine (i6A), a modified adenosine monomer, is known to induce cell death upon its addition to the culture medium. However, the molecular fate of extracellularly added i6A has yet to be identified. Here we show that i6A addition to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86e0b54cf036d491bd3a9842bae83a9d
https://doi.org/10.1261/rna.079176.122
https://doi.org/10.1261/rna.079176.122
Autor:
Sheng-Lan Shi, Hiroyuki Fukuda, Mayumi Hirayama, Kazuhito Tomizawa, Hiroyuki Oshiumi, Fan-Yan Wei, Takahiro Yamamoto, Takeshi Chujo, Taku Kaitsuka
Publikováno v:
Nucleic Acids Research
Retroviral infection requires reverse transcription, and the reverse transcriptase (RT) uses cellular tRNA as its primer. In humans, the TRMT6-TRMT61A methyltransferase complex incorporates N1-methyladenosine modification at tRNA position 58 (m1A58);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52054e2351b7e972f44783004b184e50
https://doi.org/10.1093/nar/gkab879
https://doi.org/10.1093/nar/gkab879
Autor:
Hisashi Takeshita, Ryoji Yoshida, Junki Inoue, Kohei Ishikawa, Kosuke Shinohara, Mayumi Hirayama, Toru Oyama, Ryuta Kubo, Keisuke Yamana, Yuka Nagao, Shunsuke Gohara, Junki Sakata, Hikaru Nakashima, Yuichiro Matsuoka, Masafumi Nakamoto, Masatoshi Hirayama, Kenta Kawahara, Nozomu Takahashi, Akiyuki Hirosue, Yoshikazu Kuwahara, Manabu Fukumoto, Ryo Toya, Ryuji Murakami, Hideki Nakayama
Publikováno v:
Laboratory Investigation. 103:100060
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b4bdd0c6f4c867d8642e518db61446
https://doi.org/10.1016/j.labinv.2022.100060
https://doi.org/10.1016/j.labinv.2022.100060
Autor:
Maya, Yakita, Takeshi, Chujo, Fan-Yan, Wei, Mayumi, Hirayama, Koji, Kato, Nozomu, Takahashi, Kenta, Naganuma, Masashi, Nagata, Kenta, Kawahara, Hideki, Nakayama, Kazuhito, Tomizawa
Publikováno v:
RNA (New York, N.Y.). 28(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5502f107744645eeb118cf3a8224aef4
https://pubmed.ncbi.nlm.nih.gov/35414588
https://pubmed.ncbi.nlm.nih.gov/35414588
Autor:
Hideki Nakayama, Masanori Shinohara, Ryoji Yoshida, Hisashi Takeshita, Yuko Obayashi, Kenta Kawahara, Junki Sakata, Hikaru Nakashima, Hidetaka Arita, Akimitsu Hiraki, Yuichiro Matsuoka, Mayumi Hirayama, Akiyuki Hirosue, Masashi Nagata
Publikováno v:
Oral Diseases. 27:1564-1571
OBJECTIVES To investigate whether serum amylase can predict the recovery of salivary volume and determine the correlation of the level of cytokines, including epidermal growth factor, hepatocyte growth factor and keratinocyte growth factor, with oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4ed9e856c35cc4e9ca8f7595c37826
https://doi.org/10.1111/odi.13686
https://doi.org/10.1111/odi.13686
