Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Mayumi Fujita"'
Autor:
Ryoko Araki, Tomo Suga, Yuko Hoki, Kaori Imadome, Misato Sunayama, Satoshi Kamimura, Mayumi Fujita, Masumi Abe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Genomic aberrations are a critical impediment for the safe medical use of iPSCs and their origin and developmental mechanisms remain unknown. Here we find through WGS analysis of human and mouse iPSC lines that genomic mutations are de novo
Externí odkaz:
https://doaj.org/article/c9a67a6a7e1842b9b98236430276c28b
Publikováno v:
Clinical and Translational Allergy, Vol 14, Iss 8, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/de8bc5c6d8f24cc5b2e699d6f583abdf
Autor:
Takeshi Matsubara, Fuka Ishikawa, Chisato Inuo, Mayumi Fujita, Ayumi Tsukahara, Takahiro Koyama, Hiroshi Iwamoto, Kazuhiro Miyaji
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
BackgroundWhen exclusive breastfeeding is not possible, partially hydrolyzed formula (PHF) is often used as a starter formula for infants. Some children develop allergic symptoms, including anaphylaxis, after the first intake of cow protein. Therefor
Externí odkaz:
https://doaj.org/article/c93037029cdc4b37b4f9ffae43ab74a2
Autor:
Prasanna Kumar Vaddi, Douglas Grant Osborne, Andrew Nicklawsky, Nazanin K. Williams, Dinoop Ravindran Menon, Derek Smith, Jonathan Mayer, Anna Reid, Joanne Domenico, Giang Huong Nguyen, William A. Robinson, Melanie Ziman, Dexiang Gao, Zili Zhai, Mayumi Fujita
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint expressed in regulatory T (Treg) cells and activated T lymphocytes. Despite its potential as a treatment strategy for melanoma, CTLA-4 inhibition has limited efficacy. Using
Externí odkaz:
https://doaj.org/article/b7d65bd3cb3040ed8b2065be56840d1d
Autor:
Shilpa Bhatia, Diemmy Nguyen, Laurel B. Darragh, Benjamin Van Court, Jaspreet Sharma, Michael W. Knitz, Miles Piper, Sanjana Bukkapatnam, Jacob Gadwa, Thomas E. Bickett, Shiv Bhuvane, Sophia Corbo, Brian Wu, Yichien Lee, Mayumi Fujita, Molishree Joshi, Lynn E. Heasley, Robert L. Ferris, Olga Rodriguez, Christopher Albanese, Mohit Kapoor, Elena B. Pasquale, Sana D. Karam
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
EphrinB2 and its receptor EphB4 are highly expressed in head and neck squamous cell carcinoma (HNSCC) and disrupting EphB4-ephrinB2 interaction generates sub-optimal outcomes. Here, compartmental targeting of EphB4 and ephrinB2 in HNSCC cancer cell a
Externí odkaz:
https://doaj.org/article/f51f6287a90c4406bc2348a5db38a8b9
Publikováno v:
Cancers, Vol 15, Iss 4, p 1258 (2023)
Malignant melanoma is the deadliest form of skin cancer. Despite significant efforts in sun protection education, melanoma incidence is still rising globally, drawing attention to other socioenvironmental risk factors for melanoma. Ethanol and acetal
Externí odkaz:
https://doaj.org/article/e0412cfbcef34839aa18001d249f7a50
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 16 (2022)
Background: Triple-negative breast cancer (TNBC) exhibits poor prognosis due to the lack of targets for hormonal or antibody-based therapies, thereby leading to limited success in the treatment of this cancer subtype. Poly (ADP-ribose) polymerase 1 (
Externí odkaz:
https://doaj.org/article/4e9160649fd74c02a8834e99cca12d49
Autor:
Mayumi Fujita, Kaori Imadome, Veena Somasundaram, Miki Kawanishi, Kumiko Karasawa, David A. Wink
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Metabolic reprogramming is being recognized as a fundamental hallmark of cancer, and efforts to identify drugs that can target cancer metabolism are underway. In this study, we used human breast cancer (BC) cell lines and establis
Externí odkaz:
https://doaj.org/article/3565cba2388648eea80726aef3476fb6
Autor:
Ryoko Araki, Yuko Hoki, Tomo Suga, Chizuka Obara, Misato Sunayama, Kaori Imadome, Mayumi Fujita, Satoshi Kamimura, Miki Nakamura, Sayaka Wakayama, Andras Nagy, Teruhiko Wakayama, Masumi Abe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Point mutations have been found in induced pluripotent stem cells (iPSCs) but when they arise is unclear. Here, the authors show that a G1/S cell cycle checkpoint deficiency transiently occurs early in genome reprogramming, suggesting a common develo
Externí odkaz:
https://doaj.org/article/fead58306cee46a28867f75c35cbe41b
Autor:
Victoria M Vorwald, Dana M Davis, Robert J Van Gulick, Robert J Torphy, Jessica SW Borgers, Jared Klarquist, Kasey L Couts, Carol M Amato, Dasha T Cogswell, Mayumi Fujita, Moriah J Castleman, Timothy Davis, Catherine Lozupone, Theresa M Medina, William A Robinson, Laurent Gapin, Martin D McCarter, Richard P Tobin
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives While much of the research concerning factors associated with responses to immune checkpoint inhibitors (ICIs) has focussed on the contributions of conventional peptide‐specific T cells, the role of unconventional T cells, such
Externí odkaz:
https://doaj.org/article/f3e378fd58ed4a49976a75292f42c335