Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mayuko Nagae"'
Autor:
Mayuko Nagae, Koki Yamada, Yuki Enomoto, Mari Kometani, Hitomi Tsuchida, Arvinda Panthee, Miku Nonogaki, Nao Matsunaga, Marina Takizawa, Sena Matsuzaki, Masumi Hirabayashi, Naoko Inoue, Hiroko Tsukamura, Yoshihisa Uenoyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The gonadotropin-releasing hormone (GnRH) pulse and surge are considered to be generated by arcuate kisspeptin/neurokinin B/dynorphin A (KNDy) neurons and anteroventral periventricular nucleus (AVPV) kisspeptin neurons, respectively, in fema
Externí odkaz:
https://doaj.org/article/54e1e5241b8b41a494a0848bef06fb33
Autor:
Koki YAMADA, Mayuko NAGAE, Tetsuya MANO, Hitomi TSUCHIDA, Safiullah HAZIM, Teppei GOTO, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 5, Pp 227-238 (2023)
Hypothalamic kisspeptin neurons are master regulators of mammalian reproduction via direct stimulation of gonadotropin-releasing hormone and consequent gonadotropin release. Here, we generated novel Kiss1 (kisspeptin gene)-Cre rats and investigated t
Externí odkaz:
https://doaj.org/article/bb8de6022b6f4f9e9a5e5cbfd68bce30
Autor:
Arisa SUGIMOTO, Hitomi TSUCHIDA, Mayuko NAGAE, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 68, Iss 3, Pp 190-197 (2022)
Reproductive function is suppressed during lactation owing to the suckling-induced suppression of the kisspeptin gene (Kiss1) expression in the arcuate nucleus (ARC) and subsequent suppression of luteinizing hormone (LH) release. Our previous study r
Externí odkaz:
https://doaj.org/article/52e62a9dbb8643b9a68314c018016f8c
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Endogenous opioid peptides have attracted attention as critical neuropeptides in the central mechanism regulating female reproduction ever since the discovery that arcuate dynorphin neurons that coexpress kisspeptin and neurokinin B (NKB), which are
Externí odkaz:
https://doaj.org/article/bbdbec7b087f45f3b314784477d6d250
Autor:
Kana IKEGAMI, Teppei GOTO, Sho NAKAMURA, Youki WATANABE, Arisa SUGIMOTO, Sutisa MAJARUNE, Kei HORIHATA, Mayuko NAGAE, Junko TOMIKAWA, Takuya IMAMURA, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Kei-ichiro MAEDA, Hiroko TSUKAMURA, Yoshihisa UENOYAMA
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 4, Pp 359-367 (2020)
The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the f
Externí odkaz:
https://doaj.org/article/c186e5926f0a4370bf0d6cf650553e0b
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Increasing evidence accumulated during the past two decades has demonstrated that the then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin B and dynorphin A, which were discovered in 1983 and 1979, respectively, and
Externí odkaz:
https://doaj.org/article/c43e506f00bf4cb8b7a00259c0bc8fce
Autor:
Sutisa MAJARUNE, Pelden Nima, Arisa SUGIMOTO, Mayuko NAGAE, Naoko INOUE, Hiroko TSUKAMURA, Yoshihisa UENOYAMA
Publikováno v:
The Journal of Reproduction and Development, Vol 65, Iss 5, Pp 397-406 (2019)
Increasing evidence shows that puberty onset is largely dependent on body weight rather than chronological age. To investigate the mechanism involved in the energetic control of puberty onset, the present study examined effects of chronic food restri
Externí odkaz:
https://doaj.org/article/1941fdebf5714e93a9abab28a1badea8
Autor:
Mami Oikawa, Mayuko Nagae, Naoaki Mizuno, Kenyu Iwatsuki, Fumika Yoshida, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura, Hiromitsu Nakauchi, Masumi Hirabayashi, Toshihiro Kobayashi
Publikováno v:
Molecular Reproduction and Development. 89:129-132
Gene editing in mammalian zygotes enables us to generate genetically modified animals rapidly and efficiently. In this study, we compare multiple gene targeting strategies in rat zygotes by generating a novel knock-in reporter rat line to visualize t
Autor:
Hiroko Tsukamura, Junko Tomikawa, Kei-ichiro Maeda, Youki Watanabe, Sho Nakamura, Teppei Goto, Mayuko Nagae, Arisa Sugimoto, Makoto Sanbo, Takuya Imamura, Sutisa Majarune, Kei Horihata, Kana Ikegami, Masumi Hirabayashi, Naoko Inoue, Yoshihisa Uenoyama
Publikováno v:
Journal of Reproduction and Development. 66:359-367
The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the f
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology, Vol 12 (2021)
Increasing evidence accumulated during the past two decades has demonstrated that the then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin B and dynorphin A, which were discovered in 1983 and 1979, respectively, and