Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mayuko Ishida"'
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 53:25-32
The various molecular species of lysophosphatidic acid (lysoPA) exhibit different abilities to activate the various lysoPA receptors. The composition of lysoPAs is affected by factors such as external stimulants and diseases and their profile can cha
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 53:217-226
In the current studies, we examined the molecular species of lysophosphatidic acids (lysoPAs) and their precursors in human plasma. We first examined the extraction of phospholipids under highly acidic conditions, which have been reported to allow hi
Autor:
Tatsufumi Hiramatsu, Yasukazu Takanezawa, Hiroyuki Arai, Ryo Taguchi, Rei K. Morikawa, Yutaka Sanai, Hirofumi Sonoda, Kohji Kasahara, Junken Aoki, Mayuko Ishida
Publikováno v:
Journal of Biological Chemistry. 278:49438-49447
We have identified a novel phospholipase A1, named mPA-PLA1beta, which is specifically expressed in human testis and characterized it biochemically together with previously identified mPA-PLA1alpha. The sequence of mPAPLA1beta encodes a 460-amino aci
Autor:
Hiroyuki Arai, Junken Aoki, Yuki Nagai, Keizo Inoue, Hirofumi Sonoda, Tatsufumi Hiramatsu, Mayuko Ishida, Koji Bandoh, Ryo Taguchi
Publikováno v:
Journal of Biological Chemistry. 277:34254-34263
Lysophosphatidic acid (LPA) is a lipid mediator with diverse biological properties, although its synthetic pathways have not been completely solved. We report the cloning and characterization of a novel phosphatidic acid (PA)-selective phospholipase
Autor:
Keizo Inoue, Koji Bandoh, Junken Aoki, Hiroyuki Hosono, Mayuko Ishida, Hiroyuki Arai, Yuki Nagai, Ryo Taguchi
Publikováno v:
Journal of Biological Chemistry. 276:29664-29670
Lysophosphatidylserine (1-acyl-2-lyso-PS) has been shown to stimulate histamine release from rat peritoneal mast cells (RPMC) triggered by FcepsilonRI (high affinity receptor for IgE) cross-linking, although the precise mechanism of lyso-PS productio
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 49:150-160
Autor:
Masafumi Tsujimoto, Taro Nonomura, Yuko Otani, Mayuko Ishida, Kumiko Makide, Yoshimasa Misumi, Junken Aoki, Hiroyuki Arai, Masazumi Iwashita, Tomohiko Ohwada, Ryo Taguchi
Publikováno v:
Journal of medicinal chemistry. 52(19)
In response to various exogenous stimuli, mast cells (MCs) release a wide variety of inflammatory mediators stored in their cytoplasmic granules and this release initiates subsequent allergic reactions. Lysophosphatidylserine (lysoPS) has been known
Autor:
Junken Aoki, Norio Matsuki, Hideo Ogiso, Tomoko Endo, Kuniyuki Kano, Hiroyuki Arai, Motomu Kanai, Kotaro Hama, Ryo Taguchi, Mayuko Ishida, Masayuki Tanaka, Rie Motoki, Shinichi Okudaira, Masakatsu Shibasaki
Publikováno v:
Journal of biochemistry. 146(2)
Lysophosphatidic acid (LPA) is a simple phospholipid but has numerous biological effects through a series of G-protein-coupled receptors specific to LPA. In general, LPA is short-lived when applied in vivo, which hinders most pharmacological experime
Autor:
Ayako Harada, Toshiyuki Yamazaki, Toshiaki Houjou, Masayoshi Imagawa, Mayuko Ishida, Keizou Inoue, Ryo Taguchi
Publikováno v:
Rapid communications in mass spectrometry : RCM. 18(20)
Nano-electrospray ionization (ESI) Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS) was applied to identify the molecular species of phosphatidylethanolamine of Caenorhabditis elegans, which has a high concentration of phospholip
Publikováno v:
Journal of mass spectrometry : JMS. 35(8)
A phospholipid mixture extracted from cultured cells was directly analyzed by capillary (Cap) liquid chromatography (LC)/electrospray ionization (ESI) mass spectrometry (MS). Using a quadrupole mass spectrometer, we analyzed positive molecular ions,