Development of Potent Cellular and Humoral Immune Responses in Long-Term Hemodialysis Patients After 1273-mRNA SARS-CoV-2 Vaccination

Autor: Maria Gonzalez-Perez, Maria Montes-Casado, Patricia Conde, Isabel Cervera, Jana Baranda, Marcos J. Berges-Buxeda, Mayte Perez-Olmeda, Rodrigo Sanchez-Tarjuelo, Alberto Utrero-Rico, Daniel Lozano-Ojalvo, Denis Torre, Megan Schwarz, Ernesto Guccione, Carmen Camara, M Rosario Llópez-Carratalá, Emilio Gonzalez-Parra, Pilar Portoles, Alberto Ortiz, Jose Portoles, Jordi Ochando

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Long-term hemodialysis (HD) patients are considered vulnerable and at high-risk of developing severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection due to their immunocompromised condition. Since COVID-19 associated mortality ra

Externí odkaz: https://doaj.org/article/c2a0685e3ae0484b8419bbf67f155dca

Immunogenicity of a third dose with mRNA-vaccines in the ChAdOx1-S/BNT162b2 vaccination regimen against SARS-CoV-2 variants

Autor: Javier García-Pérez, Alberto M. Borobia, Mayte Pérez-Olmeda, Antonio Portolés, Luis Castaño, Magdalena Campins-Artí, María Jesús Bertrán, Mercedes Bermejo, José Ramón Arribas, Andrea López, Ana Ascaso-del-Rio, Eunate Arana-Arri, Inmaculada Fuentes Camps, Anna Vilella, Almudena Cascajero, María Teresa García-Morales, María Castillo de la Osa, Carla Pérez Ingidua, David Lora, Paloma Jiménez-Santana, Silvia Pino-Rosa, Agustín Gómez de la Cámara, Erick De La Torre-Tarazona, Esther Calonge, Raquel Cruces, Cristóbal Belda-Iniesta, José Alcamí, Jesús Frías, Antonio J. Carcas, Francisco Díez-Fuertes, Lucía Díaz García, Elena Ramírez García, Enrique Seco Meseguer, Stefan Mark Stewart Balbàs, Alicia Marín Candón, Irene García García, Mikel Urroz Elizalde, Paula de la Rosa, Marta Sanz García, Cristina López Crespo, Vega Mauleón Martínez, Raquel de Madariaga Castell, Laura Vitón Vara, Rocío Prieto-Pérez, Emilio Vargas-Castrillón, Leonor Laredo, Ouhao Zhu-Huang, Teresa Iglesias, Natale Imaz-Ayo, Susana Meijide, Aitor García de Vicuña, Ana Santorcuato, Iraide Exposito, Sara de Benito, Alazne Bustinza, Mikel Gallego, Dolores García-Vázquez, Ana Belén de la Hoz, Gustavo Pérez-Nanclares, Josu Aurrekoetxea, Ines Urrutia, Rosa Martínez-Salazar, Janire Orcajo, Begoña Calvo, June Corcuera, Olaia Velasco, Anibal Aguayo, Xavier Martínez-Gómez, Susana Otero-Romero, Lluis Armadans, Blanca Borras-Bermejo, Oleguer Parés, Sonia Uriona, José Ángel Rodrigo Pendás, Cesar Llorente, José Santos, Laia Pinós, Lina Camacho, Judith Riera, Carla Sans, Antonia Agustí, Carmen Altadill, Carla Aguilar Blancafort, Gisela Gili Serrat, Aitana Plaza, Anna Feliu Prius, Maria Margarita Torrens, Esther Palacio, Gloria Torres, Julia Calonge, Elena Ballarin Alins, Eulàlia Pérez-Esquirol, Lourdes Vendrell Bosch, Marta Aldea, Eugènia Mellado, Ma Ángeles Marcos, Marta Tortajada, Lourdes E. Barón-Mira, Laura Granés, Sulayman Lazaar, Sara Herranz, Montserrat Malet, Sebastiana Quesada, Anna Llupià, Victoria Olivé, Antoni Trilla, Begoña Gómez, Elisenda González, Sheila Romero, Francisco Javier Gámez, Cristina Casals, Laura Burunat, Juan José Castelló, Patricia Fernández, Josep Lluís Bedini, Jordi Vila, Juan Carlos Hurtado, Isabel Jado, Giovanni Fedele, Concepción Perea, Mónica González, Isabel Grajera, María Ángeles Murillo, Pilar Balfagón, Irene Díaz-Marín, Gema González-Pardo

Publikováno v: iScience, Vol 27, Iss 9, Pp 110728- (2024)

Summary: CombiVacS study has demonstrated a strong immune response of the heterologous ChAdOx1-S/BNT162b2 vaccine combination. The primary outcomes of the study were to assess the humoral immune response against SARS-CoV-2, 28 days after a third dose

Externí odkaz: https://doaj.org/article/1d8485bc140e4998a160d76238a98bff

Pre-existing cell populations with cytotoxic activity against SARS-CoV-2 in people with HIV and normal CD4/CD8 ratio previously unexposed to the virus

Autor: Guiomar Casado-Fernández, Juan Cantón, Laura Nasarre, Fernando Ramos-Martín, Mario Manzanares, Clara Sánchez-Menéndez, Daniel Fuertes, Elena Mateos, María Aranzazu Murciano-Antón, Mayte Pérez-Olmeda, Miguel Cervero, Montserrat Torres, Rafael Rodríguez-Rosado, Mayte Coiras

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionHIV-1 infection may produce a detrimental effect on the immune response. Early start of antiretroviral therapy (ART) is recommended to preserve the integrity of the immune system. In fact, people with HIV (PWH) and normal CD4/CD8 ratio ap

Externí odkaz: https://doaj.org/article/7ba2fd5f842242518dbd56a4507606cd

PB1944: INDIVIDUALS WITH CHRONIC LYMPHOCYTIC LEUKAEMIA SHOW IMPAIRED HUMORAL BUT NORMAL CELLULAR IMMUNE RESPONSES AFTER RECEIVING A COMPLETE VACCINATION SCHEDULE AGAINST SARS-COV-2

Autor: Clara Sánchez-Menéndez, Magdalena Corona, Alejandro Zurdo, Alicia Simón-Rueda, Elena Mateos, Mario Manzanares, Javier García-Pérez, Mayte Pérez-Olmeda, Sara Rodríguez-Mora, María Aránzazu Murciano-Antón, Valentín García-Gutiérrez, Mayte Coiras, Montserrat Torres

Publikováno v: HemaSphere, Vol 7, p e08354f0 (2023)

Externí odkaz: https://doaj.org/article/f5e5b2a268e54cbc889cc6e381e62c17

The Detection of SARS-CoV-2 Antibodies in an Exposed Human Population Is Biased by the Immunoassay Used: Implications in Serosurveillance

Autor: Francisco Llorente, Elisa Pérez-Ramírez, Mayte Pérez-Olmeda, Desirée Dafouz-Bustos, Jovita Fernández-Pinero, Mercedes Martínez-Cortés, Miguel Ángel Jiménez-Clavero

Publikováno v: Pathogens, Vol 12, Iss 11, p 1360 (2023)

The presence of SARS-CoV-2 antibodies was examined over 7 months in a population of essential service workers exposed during the first epidemic wave in Madrid (Spain). Results obtained with different serological assays were compared. Firstly, serum s

Externí odkaz: https://doaj.org/article/3630884fcc41449c9072bbc00484be62