Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Mayson H. Alkhatib"'
Autor:
Raghdah S. Bawadud, Mayson H. Alkhatib
Publikováno v:
BioImpacts, Vol 13, Iss 2, Pp 145-157 (2023)
Introduction: The approach for drug delivery has impressively developed with the emergence of nanosuspension, particularly the targeted nanoemulsions (NEs). It can potentially improve the bioavailability of drugs, enhancing their therapeutic efficien
Externí odkaz:
https://doaj.org/article/a51cf9948f2e47e9b4bbecd31cdbf82a
Publikováno v:
Pharmacia, Vol 68, Iss 2, Pp 353-363 (2021)
Purpose: To investigate the modulatory effect of the natural phytochemical, carvacrol, on Topotecan (TOPO) cytotoxicity and cellular uptake in different cancer cell lines. Methods: The cytotoxicity of the carvacrol/TOPO combination therapy was determ
Externí odkaz:
https://doaj.org/article/4ea12e6515134325a2d8f35eaca62464
Publikováno v:
BioImpacts, Vol 10, Iss 1, Pp 9-16 (2020)
Introduction: Nephrotoxicity is one of the major side effects of the chemotherapeutic drug, ifosfamide (IFO). In this study, IFO was solubilized in nanoemulsion (NE) containing salvia (SAL) essential oil to investigate its adverse side effects in mic
Externí odkaz:
https://doaj.org/article/abe8324ed367471ba7e262e057ee8fa3
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 422-430 (2020)
Methotrexate (MTX), a chemotherapeutic agent, has limited clinical applications due to its pulmonary and neurotoxicity. The antineoplastic activity of MTX-NE COCO, which is MTX formulated in coconut oil nanoemulsion (NE), was evaluated in A549 non-sm
Externí odkaz:
https://doaj.org/article/22bbb292bfd44475a2be1cbf7536c2ba
Publikováno v:
Crescent Journal of Medical and Biological Sciences, Vol 5, Iss 2, Pp 76-82 (2018)
Objectives: The combination of 2 chemotherapeutic agents has been recommended in order to reduce their adverse side effects and potentiate their efficacy. The aim of the present study was to assess the antineoplastic activity of doxorubicin (DOX) com
Externí odkaz:
https://doaj.org/article/8a2147c2639b4b7cb4a5bf742c7bb88b
Publikováno v:
Journal of Microencapsulation. 39:467-480
The present study aimed to explore the sensitising capability of the anticancer agents, gemcitabine (GEM) and oxaliplatin (OXA), encapsulated in a novel SLN (GEM:OXA-SLN) against the ovarian cancer cell lines. A novel SLN, prepared using hot homogeni
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1205-1211
Purpose: To investigate the hepatotoxic and hematotoxic effects of sage oil-loaded ifosfamide (IFO) nanoemulsion (NE) in Ehrlich ascites carcinoma (EAC)-bearing mice. Methods: Ifosfamide (IFO) was loaded into a NE containing sage oil, and its hepatot
Autor:
Faiza Abdu, Huda M. Alkreathy, Ahmad Esmat, Khadijah S. Balamash, Mashael I. Al Omar, Mayson H. Alkhatib
Publikováno v:
Asian Journal of Pharmaceutical Research and Health Care. 13:17-29
Doxorubicin (DXR) is widely indicated as anticancer drug, but serious cardiotoxicity limits its clinical application. Recently, Pravastatin (PS) is one of the statins that appear to possess a potential role in cancer therapy despite its hepatotoxicit
Publikováno v:
BIOCELL. 45:695-703
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Combining more than one anticancer agent in a nanocarrier is beneficial in producing a formula with a low dose and limited adverse side effects. The current study aimed to formulate docetaxel (DTX) and thymoquinone (TQ) in borage oil-based nanoemulsi